Environmental Chemicals Modulate Polar Bear (Ursus maritimus) Peroxisome Proliferator-Activated Receptor Gamma (PPARG) and Adipogenesis in Vitro

Autor: Ingebrigt Sylte, Roger Lille-Langøy, Marte Rusten, Mari Katrine Berg, Lene Øygarden, Pawel Rostkowski, Mikael Harju, Kurt Kristiansen, Trine Fink, Heli Routti, Anders Goksøyr

Publikováno v: Routti, H, Lille-Langøy, R, Berg, M K, Fink, T, Harju, M, Kristiansen, K, Rostkowski, P, Rusten, M, Sylte, I, Øygarden, L & Goksøyr, A 2016, ' Environmental chemicals modulate polar bear (Ursus maritimus) peroxisome proliferator-activated receptor gamma (PPARG) and adipogenesis in vitro ', Environmental Science & Technology, vol. 50, no. 19, pp. 10708-10720 . https://doi.org/10.1021/acs.est.6b03020

We studied interactions between polar bear peroxisome proliferator-activated receptor gamma (pbPPARG) and selected compounds using a luciferase reporter assay and predictions through molecular docking. Furthermore, we studied adipogenesis by liver an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c09707cee53fa304171ce5789be4262c
https://doi.org/10.1021/acs.est.6b03020

mRNA expression of genes regulating lipid metabolism in ringed seals (Pusa hispida) from differently polluted areas

Autor: Marte Rusten, Martina Galatea Castelli, Anders Goksøyr, Heli Routti

Publikováno v: Aquatic Toxicology. 146:239-246

There is a growing concern about the ability of persistent organic pollutants (POPs) to influence lipid metabolism. Although POPs are found at high concentrations in some populations of marine mammals, for example in the ringed seal (Pusa hispida) fr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53cb082b9de364725cd3f0dd94bc3610
https://doi.org/10.1016/j.aquatox.2013.11.015

Effects of water regime on archaeal community composition in Arctic soils

Autor: Lone Høj, Vigdis Torsvik, Rolf A. Olsen, Lars Egil Haugen, Marte Rusten

Publikováno v: Environmental Microbiology. 8:984-996

Effects of water regime on archaeal communities in Arctic soils from Spitsbergen were studied using denaturing gradient gel electrophoresis (DGGE) of amplified 16S rRNA genes, with subsequent sequencing of amplicons and ordination analysis of binary

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5741608ea91e4f68486d9173fb633d47
https://doi.org/10.1111/j.1462-2920.2006.00982.x

Functional roles of protein kinase A (PKA) and exchange protein directly activated by 3',5'-cyclic adenosine 5'-monophosphate (cAMP) 2 (EPAC2) in cAMP-mediated actions in adrenocortical cells

Autor: Marte Rusten, Aurélia E. Lewis, Linda Aumo, Gunnar Mellgren, Marit Bakke

Publikováno v: Endocrinology. 151(5)

In the adrenal cortex, the biosynthesis of steroid hormones is controlled by the pituitary-derived hormone ACTH. The functions of ACTH are principally relayed by activating cAMP-dependent signaling pathways leading to the induction of genes encoding

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35e217d14ba7ea6b4d074d4dfad712c3
https://pubmed.ncbi.nlm.nih.gov/20233795

Seasonal Variation of Arctic Ecosystems Towards Oil Spill

Autor: Børre Johan Paaske, Marte Rusten, Øivin Aarnes, Odd Willy Brude

Publikováno v: International Oil Spill Conference Proceedings. 2014:299801

Due to melting of sea ice and predicted richness of petroleum resources, there is an increasing interest and activity in Arctic regions both for shipping and the oil&gas industry. Operations in the Arctic represent specific challenges due to both phy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4bc6aee6020f74bbe9aad839633bda57
https://doi.org/10.7901/2169-3358-2014-1-299801.1