Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Marte I. Flydal"'
Autor:
María Teresa Bueno-Carrasco, Jorge Cuéllar, Marte I. Flydal, César Santiago, Trond-André Kråkenes, Rune Kleppe, José R. López-Blanco, Miguel Marcilla, Knut Teigen, Sara Alvira, Pablo Chacón, Aurora Martinez, José M. Valpuesta
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Tyrosine hydroxylase (TH) catalyzes the rate-limiting step in the synthesis of the catecholamine neurotransmitters and hormones dopamine (DA), adrenaline and noradrenaline. Here, the authors present the cryo-EM structures of full-length human TH in t
Externí odkaz:
https://doaj.org/article/3b54c91d09444b37ba25ca02cc815dcd
Autor:
Gyrid Nygaard, Peter D. Szigetvari, Ann Kari Grindheim, Peter Ruoff, Aurora Martinez, Jan Haavik, Rune Kleppe, Marte I. Flydal
Publikováno v:
Journal of Personalized Medicine, Vol 11, Iss 11, p 1186 (2021)
Dopa-responsive dystonia (DRD) is a rare movement disorder associated with defective dopamine synthesis. This impairment may be due to the fact of a deficiency in GTP cyclohydrolase I (GTPCHI, GCH1 gene), sepiapterin reductase (SR), tyrosine hydroxyl
Externí odkaz:
https://doaj.org/article/be20b1861c08418c9e12d4f3db470b2f
Autor:
Leire Dublang, Jarl Underhaug, Marte I. Flydal, Lorea Velasco-Carneros, Jean-Didier Maréchal, Fernando Moro, Maria Dolores Boyano, Aurora Martinez, Arturo Muga
Publikováno v:
Cancers, Vol 13, Iss 12, p 2936 (2021)
Heat shock protein (Hsp) synthesis is upregulated in a wide range of cancers to provide the appropriate environment for tumor progression. The Hsp110 and Hsp70 families have been associated to cancer cell survival and resistance to chemotherapy. In t
Externí odkaz:
https://doaj.org/article/e3ccec35180a4f7c93c03249759cde84
Autor:
Trond-André Kråkenes, Mary Dayne S. Tai, Marte I. Flydal, Aurora Martinez, Knut Teigen, Maria P.A. Tran
Publikováno v:
Biochimie. 183:126-132
Tyrosine hydroxylase (TH) catalyses the (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin (BH4)-dependent conversion of L-tyrosine to L-3,4-dihydroxyphenylalanine (L-Dopa), which is the rate-limiting step in the synthesis of dopamine and other catecholamine
Autor:
Jan Haavik, Peter Ruoff, Gyrid Nygaard, Peter D. Szigetvari, Marte I. Flydal, Aurora Martinez, Rune Kleppe, Ann Kari Grindheim
Publikováno v:
Journal of Personalized Medicine
Journal of Personalized Medicine, Vol 11, Iss 1186, p 1186 (2021)
Journal of Personalized Medicine, Vol 11, Iss 1186, p 1186 (2021)
Dopa-responsive dystonia (DRD) is a rare movement disorder associated with defective dopamine synthesis. This impairment may be due to the fact of a deficiency in GTP cyclohydrolase I (GTPCHI, GCH1 gene), sepiapterin reductase (SR), tyrosine hydroxyl
Autor:
Fredrik Gullaksen Johannessen, Marte I. Flydal, Lars Skjærven, Rafael Fernandez-Leiro, Siseth Martínez-Caballero, Juan A. Hermoso, Aurora Martinez, Martín Alcorlo-Pagés
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
6 pags., 3 figs.
Phenylalanine hydroxylase (PAH) is a key enzyme in the catabo-lism of phenylalanine, and mutations in this enzyme cause phenylketonuria (PKU), a genetic disorder that leads to brain damage and mental retardation if untreated. So
Phenylalanine hydroxylase (PAH) is a key enzyme in the catabo-lism of phenylalanine, and mutations in this enzyme cause phenylketonuria (PKU), a genetic disorder that leads to brain damage and mental retardation if untreated. So
Autor:
Margaret M. Stratton, Erik I. Hallin, Rory O’Connell, Clive R. Bramham, Gopinath Muruganandam, Shreeram Akerkar, James J. Chambers, Yasunori Hayashi, Ian Merski, Petri Kursula, Helene J. Bustad, Remy Loris, Tambudzai Kanhema, Tomohisa Hosokawa, José M. Valpuesta, Marte I. Flydal, Christine Touma, Maria S. Eriksen, Daniela Lascu, Oleksii Nikolaienko, Sverre Grødem, Jorge Cuéllar, Aurora Martinez
Activity-regulated cytoskeleton-associated protein (Arc) is a protein interaction hub with diverse roles in intracellular neuronal signaling, and important functions in neuronal synaptic plasticity, memory, and postnatal cortical development. Arc has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c62aa94e02e6b1e7bc97caa5f7b99e0e
http://urn.fi/urn:nbn:fi-fe2021070140815
http://urn.fi/urn:nbn:fi-fe2021070140815
Autor:
Aurora Martinez, Fernando Moro, María Dolores Boyano, Lorea Velasco-Carneros, Jean-Didier Maréchal, Arturo Muga, Leire Dublang, Jarl Underhaug, Marte I. Flydal
Publikováno v:
Addi. Archivo Digital para la Docencia y la Investigación
instname
Cancers
Volume 13
Issue 12
Cancers, Vol 13, Iss 2936, p 2936 (2021)
Addi: Archivo Digital para la Docencia y la Investigación
Universidad del País Vasco
instname
Cancers
Volume 13
Issue 12
Cancers, Vol 13, Iss 2936, p 2936 (2021)
Addi: Archivo Digital para la Docencia y la Investigación
Universidad del País Vasco
Heat shock protein (Hsp) synthesis is upregulated in a wide range of cancers to provide the appropriate environment for tumor progression. The Hsp110 and Hsp70 families have been associated to cancer cell survival and resistance to chemotherapy. In t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4b456ae3bf061145f6401161219d295
https://hdl.handle.net/11250/2838404
https://hdl.handle.net/11250/2838404
Autor:
Knut Teigen, José Ramón López-Blanco, Pablo Chacón, Jorge Cuéllar, Rune Kleppe, Aurora Martinez, César Santiago, Marte I. Flydal, José M. Valpuesta, Trond-André Kråkenes, Sara Alvira, Teresa Bueno-Carrasco
Tyrosine hydroxylase (TH) is a highly regulated enzyme that catalyses the rate-limiting step in the biosynthesis of dopamine (DA) and other catecholamines. Mutations and dysfunction in this enzyme lead to DA deficiency and parkinsonisms of different
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::03a8c8befef21a868f87c0a99aa3f0d4
https://doi.org/10.21203/rs.3.rs-64971/v1
https://doi.org/10.21203/rs.3.rs-64971/v1
Pharmacological chaperoning by small compounds that stabilize and increase the steady-state intracellular levels of functional conformations of disease-causing protein variants is a relatively novel therapeutic approach. Customary screens are based o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a67e8ecc45e6a349ac18bd8233914f80
https://doi.org/10.1016/b978-0-12-819132-3.00015-4
https://doi.org/10.1016/b978-0-12-819132-3.00015-4