Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Marta Zaninello"'
Publikováno v:
Biology, Vol 13, Iss 9, p 746 (2024)
Mitochondria are dynamic organelles that can adjust and respond to different stimuli within a cell. This plastic ability allows them to effectively coordinate several cellular functions in cells and becomes particularly relevant in highly complex cel
Externí odkaz:
https://doaj.org/article/77bdf82541624b448f67ea8384f559c7
Autor:
Marta Zaninello, Camilla Bean
Publikováno v:
Biomolecules, Vol 13, Iss 6, p 938 (2023)
The highly specialized structure and function of neurons depend on a sophisticated organization of the cytoskeleton, which supports a similarly sophisticated system to traffic organelles and cargo vesicles. Mitochondria sustain crucial functions by p
Externí odkaz:
https://doaj.org/article/52f219becc3841ef980e2b42ae45832e
Autor:
Marta Zaninello, Konstantinos Palikaras, Deborah Naon, Keiko Iwata, Stephanie Herkenne, Ruben Quintana-Cabrera, Martina Semenzato, Francesca Grespi, Fred N. Ross-Cisneros, Valerio Carelli, Alfredo A. Sadun, Nektarios Tavernarakis, Luca Scorrano
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Autosomal dominant optic atrophy is caused by mutations in the mitochondrial fusion protein OPA1. Here, the authors show that AMPK-induced autophagy depletes mitochondria in axons of retinal ganglion cells and that autophagic inhibition reverses visi
Externí odkaz:
https://doaj.org/article/85cc1dcbdee340b78b661df3a14cc334
Autor:
Konstantinos Palikaras, Nektarios Tavernarakis, Marta Zaninello, Aggeliki Sotiriou, Luca Scorrano
Publikováno v:
Cell Death and Differentiation
Mitochondrial dysfunction and mitophagy are often hallmarks of neurodegenerative diseases such as autosomal dominant optic atrophy (ADOA) caused by mutations in the key mitochondrial dynamics protein optic atrophy 1 (Opa1). However, the second messen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0c453c0572001b4035d093f82144f74
https://doi.org/10.1038/s41418-021-00847-3
https://doi.org/10.1038/s41418-021-00847-3
Autor:
Luca Scorrano, Fred N. Ross-Cisneros, Alfredo A. Sadun, Martina Semenzato, Marta Zaninello, Francesca Grespi, Keiko Iwata, Konstantinos Palikaras, Ruben Quintana-Cabrera, Valerio Carelli, Stéphanie Herkenne, Deborah Naon, Nektarios Tavernarakis
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Digital.CSIC. Repositorio Institucional del CSIC
instname
Nature Communications
Digital.CSIC. Repositorio Institucional del CSIC
instname
Nature Communications
In autosomal dominant optic atrophy (ADOA), caused by mutations in the mitochondrial cristae biogenesis and fusion protein optic atrophy 1 (Opa1), retinal ganglion cell (RGC) dysfunction and visual loss occur by unknown mechanisms. Here, we show a ro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b68d9d44bd5e9b6e0b873f2b8850afd
https://doaj.org/article/85cc1dcbdee340b78b661df3a14cc334
https://doaj.org/article/85cc1dcbdee340b78b661df3a14cc334
Autor:
Luca Scorrano, Marta Zaninello
Publikováno v:
Pharmacological Research. 138:16-24
Retinal explants and mixed primary cultures are currently used to investigate retinal ganglion cells (RGCs) pathophysiology and pharmacology, but information on yield, quality and quantity of contaminant cells for the available RGCs enrichment techni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36e7f481134f5453dd4703b52862df3b
https://doi.org/10.1016/j.phrs.2018.07.024
https://doi.org/10.1016/j.phrs.2018.07.024
Autor:
Tatiana Varanita, Diego De Stefani, María Isabel Hernández-Alvarez, Luca Scorrano, Sowmya Lakshminaranayan, Deborah Naon, Antonio Zorzano, Stéphanie Herkenne, Francesca Grespi, Marta Giacomello, Martina Semenzato, Marta Zaninello, Annalisa Serafini, Gerald W. Dorn
Publikováno v:
Proceedings of the National Academy of Sciences. 114
We thank Filadi et al. for their comments (1) on our paper (2), where we address whether the discrepancies between their paper (3) and our original discovery of Mitofusin (Mfn) 2 as an endoplasmic reticulum (ER)–mitochondria tether (4) resulted fro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f7c30e556a534312b71f00dcf9e1670
https://doi.org/10.1073/pnas.1618610114
https://doi.org/10.1073/pnas.1618610114
Autor:
Marta Giacomello, Martina Semenzato, Luca Scorrano, Marta Zaninello, Diego De Stefani, María Isabel Hernández-Alvarez, Tatiana Varanita, Gerald W. Dorn, Annalisa Serafini, Sowmya Lakshminaranayan, Deborah Naon, Francesca Grespi, Antonio Zorzano, Stéphanie Herkenne
Significance Organelles engage in heterotypic interactions crucial for metabolic and signaling cascades. The best-studied case of this heterotypic interaction is that between the mitochondria and endoplasmic reticulum (ER), crucial for transfer of li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dc3ac29dcd9fd73c6320faa3ff74b85
https://europepmc.org/articles/PMC5056088/
https://europepmc.org/articles/PMC5056088/
Autor:
Alfredo A. Sadun, Luca Scorrano, Kostas Palikaras, Marta Zaninello, Nektarios Tavernarakis, Deborah Naon, Fred N. Ross-Cisneros, Valerio Carelli
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Bioenergetics. 1857:e108
Mitochondria are dynamic organelles that are endowed by a complex fission/fusion machinery. Fission is regulated by the Dynamin related protein 1 (DRP1), which translocates to mitochondria by calcineurin dependent dephosphorylation (Yoon et al., 2001
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a95407a00a0590dcf31cbdd38f49d935
https://doi.org/10.1016/j.bbabio.2016.04.343
https://doi.org/10.1016/j.bbabio.2016.04.343
Autor:
Roberto Simone, Marta Biagioli, Daniela Cesselli, Vittorio Gallo, Elio Raviola, Charles Plessy, Nicolas Bertin, Dejan Lazarevic, Claudio Santoro, Marta Zaninello, Christina Vlachouli, Antonio Paolo Beltrami, Isidro Ferrer, Stefano Rivella, Paola Roncaglia, Kazuto Kobayashi, Milena F. Pinto, Stefano Gustincich, Carlo Alberto Beltrami, Piero Carninci
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
Recercat. Dipósit de la Recerca de Catalunya
instname
Universidad de Barcelona
Recercat. Dipósit de la Recerca de Catalunya
instname
The mesencephalic dopaminergic (mDA) cell system is composed of two major groups of projecting cells in the substantia nigra (SN) (A9 neurons) and the ventral tegmental area (VTA) (A10 cells). A9 neurons form the nigrostriatal pathway and are involve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e712dccce4f1623f302658003fcae5f
http://hdl.handle.net/2445/141853
http://hdl.handle.net/2445/141853