Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Marta Zajacova"'
Publikováno v:
Immunology. 148:150-159
Type 1 diabetes (T1D) belongs among polygenic multifactorial autoimmune diseases. The highest risk is associated with human leucocyte antigen (HLA) class II genes, including HLA‐DQA1 gene. Our aim was to investigate DNA methylation of HLA‐DQA1 pr
Publikováno v:
Immunology Letters. 167:147-154
Objectives Extensive polymorphism of HLA class II genes is not restricted to the coding region of the gene. It extends also to the linked promoter region, where it forms the basis for different levels of individual allele’s expression. Differential
Publikováno v:
International journal of immunogenetics. 45(3)
Differential expression of HLA-DQA1 and HLA-DQB1 gene alleles was analysed in three different cell populations isolated from peripheral blood-B lymphocytes, monocytes and whole-blood cells. Interallelic differences in mRNA levels were observed: DQA1*
Publikováno v:
Human Immunology. 77:365-366
One hundred and eighty Czech individuals from the Czech Republic pop 3 were genotyped at the HLA-DRB1, -DQA1 and -DQB1 loci using sequence-specific primers PCR methods. HLA-DRB1, -DQA1 and -DQB1 genotypes are consistent with expected Hardy-Weinberg (
Autor:
Marie Cerna, Marta Zajacova, Anna Cibulova, Pavlina Cejkova, Liliana Šedová, Jan Lippert, J. Stolfa, Markéta Fojtíková, Petr Arenberger
Publikováno v:
Rheumatology international. 33(4)
Psoriatic arthritis (PsA) affects approximately 30 % of patients suffering from psoriasis vulgaris (PsV), but the risk factors for its development have not been well elucidated yet. The HLA-Cw*06 allele was described as a predisposing factor to PsV.