Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Marta Vilalta"'
Autor:
Maxime Dubail, Sophie Heinrich, Lucie Portier, Jessica Bastian, Lucia Giuliano, Lilia Aggar, Nathalie Berthault, José-Arturo Londoño-Vallejo, Marta Vilalta, Gael Boivin, Ricky A. Sharma, Marie Dutreix, Charles Fouillade
Publikováno v:
Cells, Vol 12, Iss 20, p 2435 (2023)
To rapidly assess healthy tissue toxicities induced by new anti-cancer therapies (i.e., radiation alone or in combination with drugs), there is a critical need for relevant and easy-to-use models. Consistent with the ethical desire to reduce the use
Externí odkaz:
https://doaj.org/article/ef3dbdb660124597aecf336248a066ab
Autor:
Kathleen M C Sullivan, Marta Vilalta, Linda S Ertl, Yu Wang, Carolyn Dunlap, Karen Ebsworth, Bin N Zhao, Shijie Li, Yibin Zeng, Zhenhua Miao, Pingchen Fan, Venkat Mali, Christopher Lange, Darren McMurtrie, Ju Yang, Rebecca Lui, Ryan Scamp, Vicky Chhina, Alice Kumamoto, Simon Yau, Ton Dang, Ashton Easterday, Shirley Liu, Shichang Miao, Israel Charo, Thomas J Schall, Penglie Zhang
Publikováno v:
PLoS ONE, Vol 18, Iss 6, p e0286724 (2023)
The interaction of PD-L1 with PD-1 is a major immune checkpoint that limits effector T cell function against cancer cells; monoclonal antibodies that block this pathway have been approved in multiple tumor indications. As a next generation therapy, s
Externí odkaz:
https://doaj.org/article/a53419583b96441186b367f58673ff4f
Autor:
Eui Jung Moon, Stephano S. Mello, Caiyun G. Li, Jen-Tsan Chi, Kaushik Thakkar, Jacob G. Kirkland, Edward L. Lagory, Ik Jae Lee, Anh N. Diep, Yu Miao, Marjan Rafat, Marta Vilalta, Laura Castellini, Adam J. Krieg, Edward E. Graves, Laura D. Attardi, Amato J. Giaccia
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Hypoxia plays a critical role in tumor progression including invasion and metastasis. Here, the authors screened several hypoxia inducible genes and identified the oncogenic role of MAFF in breast cancer metastasis and that it activates IL11/STAT3 pa
Externí odkaz:
https://doaj.org/article/74a0bdf041f848a69bf653962a2ec1b4
Publikováno v:
Cell Reports, Vol 8, Iss 2, Pp 402-409 (2014)
Radiotherapy (RT) is a localized therapy that is highly effective in killing primary tumor cells located within the field of the radiation beam. We present evidence that irradiation of breast tumors can attract migrating breast cancer cells. Granuloc
Externí odkaz:
https://doaj.org/article/99fea5b9457f4e8aab8a89f7fec99110
Autor:
Rehan Ali, Sandeep Apte, Marta Vilalta, Murugesan Subbarayan, Zheng Miao, Frederick T Chin, Edward E Graves
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0139425 (2015)
We evaluated the relationship between pre-treatment positron emission tomography (PET) using the hypoxic tracer 18F-[2-(2-nitro-1-H-imidazol-1-yl)-N-(2,2,3,3,3- pentafluoropropyl) acetamide] (18F-EF5) and the response of preclinical tumor models to a
Externí odkaz:
https://doaj.org/article/3d04b8edb7f64785b2a3afcac64a66d3
Autor:
Edward E. Graves, Amato J. Giaccia, Kathleen C. Horst, Allison W. Kurian, Melissa J. Jenkins, Anosheh Afghahi, Stavros Melemenidis, Yasaman Ahrari, Meghana A. Golla, Rie von Eyben, Luis A. Soto, Laura L. Bronsart, Marta Vilalta, Todd A. Aguilera, Marjan Rafat
Although radiotherapy (RT) decreases the incidence of locoregional recurrence in breast cancer, patients with triple-negative breast cancer (TNBC) have increased risk of local recurrence following breast-conserving therapy. The relationship between R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a0da5028904ca185935f29ca4d546eb8
https://doi.org/10.1158/0008-5472.c.6510065.v1
https://doi.org/10.1158/0008-5472.c.6510065.v1
Autor:
Amato J. Giaccia, Quynh-Thu Le, Alejandro Sweet-Cordero, Leanne Sayles, Dean Felsher, Phuoc T. Tran, Janine T. Erler, Ivana K. Cecic, Marta Vilalta, Edward E. Graves
CCR Translation for This Article from Hypoxia in Models of Lung Cancer: Implications for Targeted Therapeutics
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7aa2a72194ff4eef96cbd44860d2547a
https://doi.org/10.1158/1078-0432.22442201.v1
https://doi.org/10.1158/1078-0432.22442201.v1
Autor:
Amato J. Giaccia, Quynh-Thu Le, Alejandro Sweet-Cordero, Leanne Sayles, Dean Felsher, Phuoc T. Tran, Janine T. Erler, Ivana K. Cecic, Marta Vilalta, Edward E. Graves
Purpose: To efficiently translate experimental methods from bench to bedside, it is imperative that laboratory models of cancer mimic human disease as closely as possible. In this study, we sought to compare patterns of hypoxia in several standard an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02a0ff27b7915cfaf038521ac0b25315
https://doi.org/10.1158/1078-0432.c.6519002.v1
https://doi.org/10.1158/1078-0432.c.6519002.v1
Autor:
Edward E. Graves, Amato J. Giaccia, Kathleen C. Horst, Allison W. Kurian, Melissa J. Jenkins, Anosheh Afghahi, Stavros Melemenidis, Yasaman Ahrari, Meghana A. Golla, Rie von Eyben, Luis A. Soto, Laura L. Bronsart, Marta Vilalta, Todd A. Aguilera, Marjan Rafat
Table S1 summarizes the patient radiation and chemotherapy conditions. Figure S1 shows that viable tumor cells are recruited to the MFP following RT. Figure S2 shows that tumor cell recruitment is dose dependent. Figure S3 shows tumor growth curves a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::917986150f991ad817dea7058f87a903
https://doi.org/10.1158/0008-5472.22418213.v1
https://doi.org/10.1158/0008-5472.22418213.v1
Autor:
Houda, Kacem, Serena, Psoroulas, Gael, Boivin, Michael, Folkerts, Veljko, Grilj, Tony, Lomax, Adrien, Martinotti, David, Meer, Jonathan, Ollivier, Benoit, Petit, Sairos, Safai, Ricky A, Sharma, Michele, Togno, Marta, Vilalta, Damien C, Weber, Marie-Catherine, Vozenin
Publikováno v:
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology. 175
The physico-chemical and biological response to conventional and UHDR electron and proton beams was investigated, along with conventional photons. The temporal structure and nature of the beam affected both, with electron beam at ≥1400 Gy/s and pro