Zobrazeno 1 - 10
of 118
pro vyhledávání: '"Marta Varela Rey"'
Publikováno v:
Revista de Estudios e Investigación en Psicología y Educación, Iss 09 (2017)
The aim of this study is teaching adults con intellectual disability to combine symbols to convey semantic relations during shared reading. A single subject, multiple probe design across three different types of semantic relations generated from a ma
Externí odkaz:
https://doaj.org/article/270b9204a74041c4871139cf5b21f4eb
Autor:
Diego Sáenz de Urturi, Xabier Buqué, Begoña Porteiro, Cintia Folgueira, Alfonso Mora, Teresa C. Delgado, Endika Prieto-Fernández, Paula Olaizola, Beatriz Gómez-Santos, Maider Apodaka-Biguri, Francisco González-Romero, Ane Nieva-Zuluaga, Mikel Ruiz de Gauna, Naroa Goikoetxea-Usandizaga, Juan Luis García-Rodríguez, Virginia Gutierrez de Juan, Igor Aurrekoetxea, Valle Montalvo-Romeral, Eva M. Novoa, Idoia Martín-Guerrero, Marta Varela-Rey, Sanjay Bhanot, Richard Lee, Jesus M. Banales, Wing-Kin Syn, Guadalupe Sabio, María L. Martínez-Chantar, Rubén Nogueiras, Patricia Aspichueta
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
High methionine and S-adenosylmethionine serum levels are related with obesity. Here the authors show that knockdown of methionine adenosyltransferase by using antisense oligonucleotides provides beneficial effects in obesity and comorbidities.
Externí odkaz:
https://doaj.org/article/679efae112224ba6a2829203d49df6dc
Autor:
Maria J. Gonzalez-Rellan, Marcos F. Fondevila, Uxia Fernandez, Amaia Rodríguez, Marta Varela-Rey, Christelle Veyrat-Durebex, Samuel Seoane, Ganeko Bernardo, Fernando Lopitz-Otsoa, David Fernández-Ramos, Jon Bilbao, Cristina Iglesias, Eva Novoa, Cristina Ameneiro, Ana Senra, Daniel Beiroa, Juan Cuñarro, Maria DP Chantada-Vazquez, Maria Garcia-Vence, Susana B. Bravo, Natalia Da Silva Lima, Begoña Porteiro, Carmen Carneiro, Anxo Vidal, Sulay Tovar, Timo D. Müller, Johan Ferno, Diana Guallar, Miguel Fidalgo, Guadalupe Sabio, Stephan Herzig, Won Ho Yang, Jin Won Cho, Maria Luz Martinez-Chantar, Roman Perez-Fernandez, Miguel López, Carlos Dieguez, Jose M. Mato, Oscar Millet, Roberto Coppari, Ashwin Woodhoo, Gema Fruhbeck, Ruben Nogueiras
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-21 (2021)
p53 regulates signalling pathways involved in metabolic homeostasis. Here the authors show that O-GlcNAcylation of p53 in the liver plays a key role in the physiological regulation of glucose homeostasis, potentially via controlling the expression of
Externí odkaz:
https://doaj.org/article/9769f87dfa1c4d5b90bfa5688f97fb4c
Autor:
Lucía Barbier-Torres, Karen A. Fortner, Paula Iruzubieta, Teresa C. Delgado, Emily Giddings, Youdinghuan Chen, Devin Champagne, David Fernández-Ramos, Daniela Mestre, Beatriz Gomez-Santos, Marta Varela-Rey, Virginia Gutiérrez de Juan, Pablo Fernández-Tussy, Imanol Zubiete-Franco, Carmelo García-Monzón, Águeda González-Rodríguez, Dhaval Oza, Felipe Valença-Pereira, Qian Fang, Javier Crespo, Patricia Aspichueta, Frederic Tremblay, Brock C. Christensen, Juan Anguita, María Luz Martínez-Chantar, Mercedes Rincón
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Non-alcoholic fatty liver (NAFLD) disease causes degeneration of the liver, affects about 25% of people globally, and has no approved treatment. Here, the authors show that the therapeutic siRNA-driven silencing of MCJ in the liver is an effective an
Externí odkaz:
https://doaj.org/article/f4585c15ec8641c2ad4a105f86c1a9ca
Autor:
Pablo Fernández-Tussy, David Fernández-Ramos, Fernando Lopitz-Otsoa, Jorge Simón, Lucía Barbier-Torres, Beatriz Gomez-Santos, Maitane Nuñez-Garcia, Mikel Azkargorta, Virginia Gutiérrez-de Juan, Marina Serrano-Macia, Rubén Rodríguez-Agudo, Paula Iruzubieta, Juan Anguita, Rui E. Castro, Devin Champagne, Mercedes Rincón, Felix Elortza, Anita Arslanow, Marcin Krawczyk, Frank Lammert, Mélanie Kirchmeyer, Iris Behrmann, Javier Crespo, Shelly C. Lu, José M. Mato, Marta Varela-Rey, Patricia Aspichueta, Teresa C. Delgado, María L. Martínez-Chantar
Publikováno v:
Molecular Metabolism, Vol 29, Iss , Pp 40-54 (2019)
Objective: Non-alcoholic fatty liver disease (NAFLD) is a complex pathology in which several dysfunctions, including alterations in metabolic pathways, mitochondrial functionality and unbalanced lipid import/export, lead to lipid accumulation and pro
Externí odkaz:
https://doaj.org/article/a17e13bf601849f78b91e8ef169b6cb2
Autor:
Imanol Zubiete-Franco, Juan L. García-Rodríguez, Fernando Lopitz-Otsoa, Marina Serrano-Macia, Jorge Simon, Pablo Fernández-Tussy, Lucía Barbier-Torres, David Fernández-Ramos, Virginia Gutiérrez-de-Juan, Sergio López de Davalillo, Onintza Carlevaris, Adolfo Beguiristain Gómez, Erica Villa, Diego Calvisi, César Martín, Edurne Berra, Patricia Aspichueta, Naiara Beraza, Marta Varela-Rey, Matias Ávila, Manuel S. Rodríguez, José M. Mato, Irene Díaz-Moreno, Antonio Díaz-Quintana, Teresa C. Delgado, María L. Martínez-Chantar
Publikováno v:
EBioMedicine, Vol 40, Iss , Pp 406-421 (2019)
Background: Even though liver kinase B1 (LKB1) is usually described as a tumor suppressor in a wide variety of tissues, it has been shown that LKB1 aberrant expression is associated with bad prognosis in Hepatocellular Carcinoma (HCC). Methods: Herei
Externí odkaz:
https://doaj.org/article/e999866377054581b7ff898019281bf5
Autor:
María Juárez‐Fernández, Naroa Goikoetxea‐Usandizaga, David Porras, María Victoria García‐Mediavilla, Miren Bravo, Marina Serrano‐Maciá, Jorge Simón, Teresa C. Delgado, Sofía Lachiondo‐Ortega, Susana Martínez‐Flórez, Óscar Lorenzo, Mercedes Rincón, Marta Varela‐Rey, Leticia Abecia, Héctor Rodríguez, Juan Anguita, Esther Nistal, María Luz Martínez‐Chantar, Sonia Sánchez‐Campos
Publikováno v:
Hepatology. 77:1654-1669
[EN] Background and Aims: Recent studies suggest that mitochondrial dysfunction promotes progression to NASH by aggravating the gut-liver status. However, the underlying mechanism remains unclear. Herein, we hypothesized that enhanced mitochondrial a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1243cd8aaa221632ef2dd1fd4559300
https://doi.org/10.1002/hep.32705
https://doi.org/10.1002/hep.32705
Autor:
Lucía Barbier-Torres, Paula Iruzubieta, David Fernández-Ramos, Teresa C. Delgado, Daniel Taibo, Virginia Guitiérrez-de-Juan, Marta Varela-Rey, Mikel Azkargorta, Nicolas Navasa, Pablo Fernández-Tussy, Imanol Zubiete-Franco, Jorge Simon, Fernando Lopitz-Otsoa, Sofia Lachiondo-Ortega, Javier Crespo, Steven Masson, Misti Vanette McCain, Erica Villa, Helen Reeves, Felix Elortza, Maria Isabel Lucena, Maria Isabel Hernández-Alvarez, Antonio Zorzano, Raúl J. Andrade, Shelly C. Lu, José M. Mato, Juan Anguita, Mercedes Rincón, María Luz Martínez-Chantar
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Acetaminophen-induced liver injury is one of the most common causes of liver failure and has to be treated within hours of the overdose. Here Barbier-Torres et al. show that targeting MCJ, a mitochondrial negative regulator, even 24 h after the overd
Externí odkaz:
https://doaj.org/article/a9c4f7b07bb74956911d961a97c3a9d5
Autor:
Patricia Aspichueta, Ana M. Zubiaga, Luis Castaño, Maria L. Martínez-Chantar, Jesus M. Banales, Javier Crespo, Paula Iruzubieta, Idoia Martinez de la Piscina, Sonia Gaztambide, Lorena Mosteiro, Gaizka Errazti, Maria J. Perugorria, Igotz Delgado, Sanjay Bhanot, Richard Lee, Naroa Goikoetxea-Usandizaga, Teresa C. Delgado, Virginia Gutierrez De Juan, Irantzu Bernales, Ainhoa Iglesias-Ara, Xabier Buqué, Larraitz Fernández-Ares, Juan L. García-Rodríguez, Maitane Núñez-García, Diego Sáenz de Urturi, Beatriz Gómez-Santos, Marta Palomo-Irigoyen, Marta Varela-Rey, Miguel Tamayo-Caro, Ashwin Woodhoo, Jesper B. Andersen, Colm J. O'Rourke, Igor Aurrekoetxea, Daniela Mestre, Francisco González-Romero
Supplementary Table 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ddf213946fc87fd4f283ab64b4cde07
https://doi.org/10.1158/0008-5472.22430244
https://doi.org/10.1158/0008-5472.22430244
Autor:
Patricia Aspichueta, Ana M. Zubiaga, Luis Castaño, Maria L. Martínez-Chantar, Jesus M. Banales, Javier Crespo, Paula Iruzubieta, Idoia Martinez de la Piscina, Sonia Gaztambide, Lorena Mosteiro, Gaizka Errazti, Maria J. Perugorria, Igotz Delgado, Sanjay Bhanot, Richard Lee, Naroa Goikoetxea-Usandizaga, Teresa C. Delgado, Virginia Gutierrez De Juan, Irantzu Bernales, Ainhoa Iglesias-Ara, Xabier Buqué, Larraitz Fernández-Ares, Juan L. García-Rodríguez, Maitane Núñez-García, Diego Sáenz de Urturi, Beatriz Gómez-Santos, Marta Palomo-Irigoyen, Marta Varela-Rey, Miguel Tamayo-Caro, Ashwin Woodhoo, Jesper B. Andersen, Colm J. O'Rourke, Igor Aurrekoetxea, Daniela Mestre, Francisco González-Romero
Lipid metabolism rearrangements in nonalcoholic fatty liver disease (NAFLD) contribute to disease progression. NAFLD has emerged as a major risk for hepatocellular carcinoma (HCC), where metabolic reprogramming is a hallmark. Identification of metabo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a5c6a7e5944231bd4c670412d55b9a1
https://doi.org/10.1158/0008-5472.c.6513576.v1
https://doi.org/10.1158/0008-5472.c.6513576.v1