Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Marta Tarquis Medina"'
Autor:
Mostafa Bakhti, Aimée Bastidas-Ponce, Sophie Tritschler, Oliver Czarnecki, Marta Tarquis-Medina, Eva Nedvedova, Jessica Jaki, Stefanie J. Willmann, Katharina Scheibner, Perla Cota, Ciro Salinno, Karsten Boldt, Nicola Horn, Marius Ueffing, Ingo Burtscher, Fabian J. Theis, Ünal Coskun, Heiko Lickert
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
How pancreatic islets of Langerhans are built during development is incompletely understood. Here the authors find that Synaptotagmin-13 mediates remodeling of cell-matrix adhesion to regulate endocrine cell egression and islet morphogenesis.
Externí odkaz:
https://doaj.org/article/dcf6d7a49bfe4f828b9bce5036064d2d
Autor:
Mostafa Bakhti, Katharina Scheibner, Sophie Tritschler, Aimée Bastidas-Ponce, Marta Tarquis-Medina, Fabian J. Theis, Heiko Lickert
Publikováno v:
Molecular Metabolism, Vol 30, Iss , Pp 16-29 (2019)
Objective: Translation of basic research from bench-to-bedside relies on a better understanding of similarities and differences between mouse and human cell biology, tissue formation, and organogenesis. Thus, establishing ex vivo modeling systems of
Externí odkaz:
https://doaj.org/article/27b5e6fddb4a44608e45283be15f96ea
Autor:
Nirav Florian Chhabra, Anna–Lena Amend, Aimée Bastidas-Ponce, Sibylle Sabrautzki, Marta Tarquis-Medina, Stephan Sachs, Marina Rubey, Bettina Lorenz-Depiereux, Annette Feuchtinger, Mostafa Bakhti, Heiko Lickert, Gerhard K.H. Przemeck, Martin Hrabě de Angelis
Publikováno v:
Molecular Metabolism, Vol 54, Iss , Pp 101334- (2021)
Objective: Protein disulfide isomerases (PDIs) are oxidoreductases that are involved in catalyzing the formation and rearrangement of disulfide bonds during protein folding. One of the PDI members is the PDI-associated 6 (PDIA6) protein, which has be
Externí odkaz:
https://doaj.org/article/d2d439c9b5274d6bbb1ff4d1a2b17488
Autor:
Ciro Salinno, Maren Büttner, Perla Cota, Sophie Tritschler, Marta Tarquis-Medina, Aimée Bastidas-Ponce, Katharina Scheibner, Ingo Burtscher, Anika Böttcher, Fabian J. Theis, Mostafa Bakhti, Heiko Lickert
Publikováno v:
Molecular Metabolism, Vol 49, Iss , Pp 101188- (2021)
Objective: Islets of Langerhans contain heterogeneous populations of insulin-producing β-cells. Surface markers and respective antibodies for isolation, tracking, and analysis are urgently needed to study β-cell heterogeneity and explore the mechan
Externí odkaz:
https://doaj.org/article/ded8c860e8e34738b2ec3e958075fae9
Autor:
Marta Tarquis-Medina, Katharina Scheibner, Ismael González-García, Aimée Bastidas-Ponce, Michael Sterr, Jessica Jaki, Silvia Schirge, Cristina García-Cáceres, Heiko Lickert, Mostafa Bakhti
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 22, p 12526 (2021)
Synaptotagmin-13 (Syt13) is an atypical member of the vesicle trafficking synaptotagmin protein family. The expression pattern and the biological function of this Ca2+-independent protein are not well resolved. Here, we have generated a novel Syt13-V
Externí odkaz:
https://doaj.org/article/4823f1a594184ccd8b7d615cfc60b619
Autor:
Dominik Klein, Giovanni Palla, Marius Lange, Michal Klein, Zoe Piran, Manuel Gander, Laetitia Meng-Papaxanthos, Michael Sterr, Aimée Bastidas-Ponce, Marta Tarquis-Medina, Heiko Lickert, Mostafa Bakhti, Mor Nitzan, Marco Cuturi, Fabian J. Theis
Single-cell genomics technologies enable multimodal profiling of millions of cells across temporal and spatial dimensions. Experimental limitations prevent the measurement of all-encompassing cellular states in their native temporal dynamics or spati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::50b59ee5c2043e337fec8b03b539ec3a
https://doi.org/10.1101/2023.05.11.540374
https://doi.org/10.1101/2023.05.11.540374
Autor:
Ingo Burtscher, Marta Tarquis-Medina, Ciro Salinno, Silvia Schirge, Julia Beckenbauer, Mostafa Bakhti, Heiko Lickert
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 7, p 3434 (2021)
Nkx6-1 is a member of the Nkx family of homeodomain transcription factors (TFs) that regulates motor neuron development, neuron specification and pancreatic endocrine and β-cell differentiation. To facilitate the isolation and tracking of Nkx6-1-exp
Externí odkaz:
https://doaj.org/article/fff40fe460454f95bf15c9f8d7f6e7bb
Autor:
Ciro Salinno, Perla Cota, Aimée Bastidas-Ponce, Marta Tarquis-Medina, Heiko Lickert, Mostafa Bakhti
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 21, p 5417 (2019)
The exponential increase of patients with diabetes mellitus urges for novel therapeutic strategies to reduce the socioeconomic burden of this disease. The loss or dysfunction of insulin-producing β-cells, in patients with type 1 and type 2 diabetes
Externí odkaz:
https://doaj.org/article/d134e98b27e24cb0b4eccab6b4bd1948
Autor:
Marina Rubey, Mostafa Bakhti, Nirav Florian Chhabra, Stephan Sachs, Marta Tarquis-Medina, Bettina Lorenz-Depiereux, Heiko Lickert, Annette Feuchtinger, Sibylle Sabrautzki, Anna–Lena Amend, Martin Hrabě de Angelis, Aimée Bastidas-Ponce, Gerhard K. H. Przemeck
Publikováno v:
Molecular Metabolism
Mol. Metab. 54:101334 (2021)
Molecular Metabolism, Vol 54, Iss, Pp 101334-(2021)
Mol. Metab. 54:101334 (2021)
Molecular Metabolism, Vol 54, Iss, Pp 101334-(2021)
Objective Protein disulfide isomerases (PDIs) are oxidoreductases that are involved in catalyzing the formation and rearrangement of disulfide bonds during protein folding. One of the PDI members is the PDI-associated 6 (PDIA6) protein, which has bee
Autor:
Ciro Salinno, Katharina Scheibner, Stefanie J. Willmann, Ingo Burtscher, Perla Cota, Nicola Horn, Jessica Jaki, Mostafa Bakhti, Marius Ueffing, Fabian J. Theis, Marta Tarquis-Medina, Eva Nedvedova, Heiko Lickert, Sophie Tritschler, Aimée Bastidas-Ponce, Ünal Coskun, Karsten Boldt
Epithelial cell egression is important for organ development, but also drives cancer metastasis. Better understandings of pancreatic epithelial morphogenetic programs generating islets of Langerhans aid to diabetes therapy. Here we identify the Ca2+-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::96c7ccc903ba786c7b77392fcaa75f05
https://doi.org/10.1101/2021.08.30.458251
https://doi.org/10.1101/2021.08.30.458251