Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Marta Subias"'
Autor:
Javier Lumbreras, Marta Subias, Natalia Espinosa, Juana María Ferrer, Emilia Arjona, Santiago Rodríguez de Córdoba
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Thrombotic microangiopathy (TMA) has different etiological causes, and not all of them are well understood. In atypical hemolytic uremic syndrome (aHUS), the TMA is caused by the complement dysregulation associated with pathogenic mutations in comple
Externí odkaz:
https://doaj.org/article/27492a126dd9411c98f483db48b352d4
Autor:
Sara Gómez, Javier Querol-García, Gara Sánchez-Barrón, Marta Subias, Àlex González-Alsina, Virginia Franco-Hidalgo, Sebastián Albertí, Santiago Rodríguez de Córdoba, Francisco J. Fernández, M. Cristina Vega
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
The ubiquitous and highly abundant glycolytic enzyme D-glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is pivotal for the energy and carbon metabolism of most organisms, including human pathogenic bacteria. For bacteria that depend mostly on glycoly
Externí odkaz:
https://doaj.org/article/e00b8250695743a9beb16b516e0b8969
In warm inflation, dissipation due to the interactions of the inflaton field to other light degrees of freedom leads naturally to the enhancement of the primordial spectrum during the last 10-20 efolds of inflation. We study this effect in a variant
Externí odkaz:
http://arxiv.org/abs/2105.08045
Autor:
Francisco Javier Cañada, Constantino Fernández, Elena Gómez-Rubio, Sonsoles Martín-Santamaría, Amaia Pereda, Marta Subias, Lucía López, Héctor Martín Merinero, Elena Goicoechea de Jorge, Santiago Rodríguez de Córdoba
33 p.-7 fig.
Factor H-related proteins (FHRs) are a group of partly characterized complement proteins that are thought to promote complement activation by competing binding of factor H (FH) to surface-bound C3b. Among them, FHR-1 is remarkable b
Factor H-related proteins (FHRs) are a group of partly characterized complement proteins that are thought to promote complement activation by competing binding of factor H (FH) to surface-bound C3b. Among them, FHR-1 is remarkable b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fca5ddaa7d3a934e5e19e23e5644c54
http://hdl.handle.net/10261/236465
http://hdl.handle.net/10261/236465
Autor:
Martín Alcorlo, Oscar Llorca, Andrés López-Perrote, Marta Subias, Dimitrios Morikis, Reed E.S. Harrison, Santiago Rodríguez de Córdoba
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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C3b, the central component of the alternative pathway (AP) of the complement system, coexists as a mixture of conformations in solution. These conformational changes can affect interactions with other proteins and complement regulators. Here we combi
Autor:
Anaïs Jiménez-Reinoso, Simon J. Freeley, Santiago Rodríguez de Córdoba, Martin Kolev, Margarita López-Trascasa, Alberto López-Lera, Cindy S. Ma, Stuart G. Tangye, José R. Regueiro, Elena Román-Ortiz, Marta Subias, Kathryn Payne, Ana V. Marin, Giuseppina Arbore, Claudia Kemper, Edgar Fernández-Malavé
Publikováno v:
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
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E-Prints Complutense. Archivo Institucional de la UCM
Jiménez-Reinoso, A, Marin, A V, Subias, M, López-Lera, A, Román-Ortiz, E, Payne, K, Ma, C S, Arbore, G, Kolev, M, Freeley, S J, Kemper, C, Tangye, S G, Fernández-Malavé, E, Rodríguez de Córdoba, S, López-Trascasa, M & Regueiro, J R 2017, ' Human plasma C3 is essential for the development of memory B, but not T, lymphocytes ', Journal of Allergy and Clinical Immunology . https://doi.org/10.1016/j.jaci.2017.09.037
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname
E-Prints Complutense. Archivo Institucional de la UCM
Jiménez-Reinoso, A, Marin, A V, Subias, M, López-Lera, A, Román-Ortiz, E, Payne, K, Ma, C S, Arbore, G, Kolev, M, Freeley, S J, Kemper, C, Tangye, S G, Fernández-Malavé, E, Rodríguez de Córdoba, S, López-Trascasa, M & Regueiro, J R 2017, ' Human plasma C3 is essential for the development of memory B, but not T, lymphocytes ', Journal of Allergy and Clinical Immunology . https://doi.org/10.1016/j.jaci.2017.09.037
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6637bf2155281caece3ca11ec0a5d51
https://fundanet.iislafe.san.gva.es/publicaciones/ProdCientif/PublicacionFrw.aspx?id=7074
https://fundanet.iislafe.san.gva.es/publicaciones/ProdCientif/PublicacionFrw.aspx?id=7074
Autor:
Miriam Galbusera, Mercedes Domínguez, B. Paul Morgan, Ana Villegas-Martínez, Marta Subias, Oscar Llorca, Marina Noris, Sara Gastoldi, Agustín Tortajada, Andrés López-Perrote, Lucía López, Fernando A. González-Fernández, Santiago Rodríguez de Córdoba
Publikováno v:
The Journal of Immunology. 193:5567-5575
The alternative pathway (AP) is critical for the efficient activation of complement regardless of the trigger. It is also a major player in pathogenesis, as illustrated by the long list of diseases in which AP activation contributes to pathology. Its
Autor:
Behdad Afzali, Margaret H. Y. Ma, Antonella F. Fara, John P. Atkinson, Thomas Reinheckel, Paula Bertram, Marta Subias, Seppo Meri, Christian Drouet, Pirkka T. Pekkarinen, T. Petteri Arstila, Marilyn K. Leung, Matthew C. Pickering, Gaelle Le Friec, M. Kathryn Liszewski, Andrew P. Cope, Claudia Kemper, Santiago Rodríguez de Córdoba, Martin Kolev
Publikováno v:
Immunity
Summary Complement is viewed as a critical serum-operative component of innate immunity, with processing of its key component, C3, into activation fragments C3a and C3b confined to the extracellular space. We report here that C3 activation also occur
Autor:
Santiago Rodríguez de Córdoba, Jaouad Anter, Miquel Blasco, Rosa M. Coco, Ramona Maranta, Alfredo García-Layana, Sergio Recalde, Sheila Pinto, Marta Subias, Marina Noris, Agustín Tortajada
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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27 p.-3 fig.-1 tab.-3 fig. compl.
The complement factor H (FH) mutation R1210C, which was described in association with atypical hemolytic uremic syndrome (aHUS), also confers high risk of age-related macular degeneration (AMD) and associates wi
The complement factor H (FH) mutation R1210C, which was described in association with atypical hemolytic uremic syndrome (aHUS), also confers high risk of age-related macular degeneration (AMD) and associates wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f6ebac7dc1fe7298a0de27ca829fda8
http://hdl.handle.net/10261/122411
http://hdl.handle.net/10261/122411
Autor:
Martín Alcorlo, Oscar Llorca, César Rodríguez-Gallego, Hugo Yebenes, Santiago Rodríguez de Córdoba, Andrés López-Perrote, Sandra Delgado, Marta Subias
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
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21 p.-6 fig.
The proteolytic cleavage of C3 to generate C3b is the central and most important step in the activation of Complement, a major component of innate immunity. The comparison of the crystal structures of C3 and C3b illustrates large co
The proteolytic cleavage of C3 to generate C3b is the central and most important step in the activation of Complement, a major component of innate immunity. The comparison of the crystal structures of C3 and C3b illustrates large co