Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Marta Sowinska"'
Autor:
Marta Sowinska, Maja Morawiak, Marta Bochyńska-Czyż, Andrzej W. Lipkowski, Elżbieta Ziemińska, Barbara Zabłocka, Zofia Urbanczyk-Lipkowska
Publikováno v:
Biomolecules, Vol 9, Iss 3, p 89 (2019)
Background: Exposure to ozone level and ultraviolet (UV) radiation is one of the major concerns in the context of public health. Numerous studies confirmed that abundant free radicals initiate undesired processes, e.g. carcinogenesis, cells degenerat
Externí odkaz:
https://doaj.org/article/986f4cc0a67447119ae4d2df7c1638d4
Autor:
Krzysztof Brzózka, Alan P. Watt, Michal Galezowski, Magdalena Mroczkowska, Stefan Chmielewski, Grzegorz Witold Topolnicki, Christopher A. Gabel, David J. Schultz, John R. Doedens, Charles-Henry Fabritius, Oleksandr Levenets, Piotr Kowalczyk, Piotr Urbanski, Katarzyna Palica, Nicolas Boutard, Anna Cierpich, Roderick A. Porter, Marta Bugaj, Jakub Woyciechowski, Marta Sowinska, David G. Harrison
Publikováno v:
Bioorganicmedicinal chemistry letters. 30(23)
The NLRP3 inflammasome is a component of the innate immune system involved in the production of proinflammatory cytokines. Aberrant activation by a wide range of exogenous and endogenous signals can lead to chronic, low-grade inflammation. It has att
Autor:
Marta Bochyńska-Czyż, Anna Laskowska, Adam Guśpiel, Zofia Urbanczyk-Lipkowska, Jolanta Solecka, Andrzej W. Lipkowski, Marta Sowinska, Katarzyna Trzeciak
Publikováno v:
Bioconjugate Chemistry. 29:3571-3585
Evolution-derived natural compounds have been inspirational for design of numerous pharmaceuticals, e.g., penicillins and tetracyclines. Herein, we present a bioinspired strategy to design peptide dendrimers for the effective therapy of E. coli infec
Autor:
Kinga Michalik, Peter Littlewood, Karolina Gluza, Katarzyna Banaszak, Agata Dudek, Agnieszka Piatek, Marta Bugaj, Sujit Sasmal, Adam Radzimierski, Michal Galezowski, Eliza Zimolag, Pawel Guzik, Magdalena Zastawna, Marta Sowinska, Krzysztof Brzózka, Joanna Szeremeta-Spisak, Stefan Chielewski, Oleksandr Levenets, Przemysław Wyrębek, Anna Zagorska, Adrian Podkowa, Aniela Golas, Iana Levenets, Maciej Kujawa, Martin Swarbrick, Stefan Chmielewski, Patryk Kret, Andrzej Gondela, Mateusz Swirski, Sylwia Sudoł, Dominika Stanko, Agnieszka Gibas, Marianna Girardi, Karol Zuchowicz, Mateusz Ogórek, Marcin Nowogrodzki, Paulina Niedziejko
Publikováno v:
Journal for ImmunoTherapy of Cancer. 9:A786-A786
BackgroundHematopoietic progenitor kinase 1 (HPK1, MAP4K1) is emerging as a well-renowned, druggable target for T cell-based immunotherapies. HPK1 is a member of the serine/threonine MAP4K family, predominantly expressed in hematopoietic cell lineage
Autor:
Zofia Urbanczyk-Lipkowska, Monika Szeliga, Barbara Zabłocka, Marta Sowinska, Elzbieta Zieminska, Maja Morawiak
Publikováno v:
Biomolecules, Vol 11, Iss 435, p 435 (2021)
Biomolecules
Volume 11
Issue 3
Biomolecules
Volume 11
Issue 3
Background: Glioblastoma (GBM) is the most common malignant tumor of the central nervous system (CNS). Neuroblastoma (NB) is one of the most common cancers of childhood derived from the neural crest cells. The survival rate for patients with GBM and
Autor:
K. Banaszak, M. Gaik, M. Maciuszek, A. Gondela, A. Stachowicz, A. Bialas, A. Kitlinska, K. Kwiecinska, H.M. Eggenweiler, M. Bien, L. Wloszczak, Mateusz Michał Tomczyk, P. Guzik, Magdalena Sieprawska-Lupa, Piotr Kowalczyk, M. Jurzak, Marta Sowinska, M. Les, Mateusz Nowak, Aleksandra Sabiniarz, S. Ziemianska, B. Bugaj, Maciej Mikulski, Nicolas Boutard, L. Dudek, Anna Cierpich, A. Biela, R. Lindemann, Adrian Zarebski, H. Pawlik, J. Fogt, E. Cieluch, Joanna Szeremeta-Spisak, Krzysztof Brzózka, T. Rzymski, M. Kujawa, K. Jakubiec, C.H. Fabritius, Katarzyna Wiklik, A. Obara, Anna Buda, P. Niedziejko
Publikováno v:
ChemMedChem. 14(1)
Energy and biomass production in cancer cells are largely supported by aerobic glycolysis in what is called the Warburg effect. The process is regulated by key enzymes, among which phosphofructokinase PFK-2 plays a significant role by producing fruct
Publikováno v:
Beta-Lactams ISBN: 9783319556208
Traditional antimicrobial therapy used today at clinics is mainly focused on application of developed several decades ago several classes of small chemically modified organic compounds of natural origin, e.g. penicillins, cephalosporins, macrolides,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc9c1432a912640c0a64ba25a0400786
https://doi.org/10.1007/978-3-319-55621-5_10
https://doi.org/10.1007/978-3-319-55621-5_10
Autor:
Agnieszka Przybylowicz, Marta Sowinska, Krzysztof Brzózka, Agnieszka Adamus, Pawel Guzik, Marcin Król, Urszula Kulesza, Przemyslaw Golik, Mateusz Nowak, Tomasz Rzymski, Karolina Gluza, Justyna Wujkowska, Nicolas Boutard, Piotr Kowalczyk, Magdalena Sieprawska-Lupa, David J. Schultz, Anna Wrobel, Karolina Pyziak, Agnieszka Sroka-Porada, Magdalena Zastawna, Anna Bartosik, Agnieszka Dreas, Faustyna Iwanska
Publikováno v:
Cancer Research. 78:3516-3516
Over-activation of the serine synthesis pathway, upregulation of SHMT2 has been described in over 20% of solid tumors (e.g. breast, lung, colorectal cancers). Such cancer cells are highly dependent on serine. Serine hydroxymethyltransferase (SHMT) pl
Autor:
Damian Kobylarz, Maciej Noga, Adrian Frydrych, Justyna Milan, Adrian Morawiec, Agata Glaca, Emilia Kucab, Julia Jastrzębska, Karolina Jabłońska, Klaudia Łuc, Gabriela Zdeb, Jakub Pasierb, Joanna Toporowska-Kaźmierak, Szczepan Półchłopek, Paweł Słoma, Magdalena Adamik, Mateusz Banasik, Mateusz Bartoszek, Aleksandra Adamczyk, Patrycja Rędziniak, Paulina Frączkiewicz, Michał Orczyk, Martyna Orzechowska, Paulina Tajchman, Klaudia Dziuba, Rafał Pelczar, Sabina Zima, Yana Nyankovska, Marta Sowińska, Wiktoria Pempuś, Maria Kubacka, Julia Popielska, Patryk Brzezicki, Kamil Jurowski
Publikováno v:
Toxics, Vol 11, Iss 9, p 723 (2023)
Poisoning and overdose are very important aspects in medicine and toxicology. Chemical weapons pose a threat to civilians, and emergency medicine principles must be followed when dealing with patients who have been poisoned or overdosed. Antidotes ha
Externí odkaz:
https://doaj.org/article/c2c5d3f266214f4cb88a95ce95fa4909
Autor:
Tomasz Rzymski, Pawel Guzik, Marcin Król, Artur Biela, Agnieszka Przybylowicz, Anna Wrobel, Marta Sowinska, Karolina Pyziak, Agnieszka Sroka, Agnieszka Dreas, Magdalena Sieprawska-Lupa, Katarzyna Hamara, Krzysztof Brzózka, Agnieszka Adamus
Publikováno v:
Cancer Research. 77:442-442
Many oncogenes modulate metabolic pathways and altered metabolism is one of the hallmarks of cancer. In order to sustain proliferation, cell growth and adopt to a very specific tumor microenvironment, cancer cells have to undergo metabolic reprogramm