Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Marta Sirova"'
Autor:
Silvia Pastorekova, Veronika Liskova, Olga Krizanova, Filippo Iuliano, Marta Sirova, Karol Ondrias, Lubomira Lencesova, Sona Hudecova
Publikováno v:
Cancers, Vol 11, Iss 8, p 1139 (2019)
Cancers
Volume 11
Issue 8
Cancers
Volume 11
Issue 8
Hypoxia and acidosis are among the key microenvironmental factors that contribute to cancer progression. We have explored a possibility that the type 1Na+/Ca2+ exchanger (NCX1) is involved in pH control in hypoxic tumors. We focused on changes in int
Autor:
Tibor Stračina, Jan Sedlak, Jana Markova, Paulina Gronesova, Veronika Simko, Marie Nováková, Marta Sirova, Juraj Kopacek, Sona Hudecova, Eliska Svastova, Silvia Pastorekova, Dana Cholujova, Lucia Csaderova, Olga Krizanova, Michal Pastorek, Michaela Fojtu
Publikováno v:
Oncotarget
In this study we show that anti-tumor effect of sulforaphane (SFN) is partially realized through the type 1 inositol 1,4,5-trisphosphate receptor (IP3R1). This effect was verified in vitro on three different stable cell lines and also in vivo on the
Autor:
Andrea Soltysova, Marta Sirova, Karol Ondrias, Lubomira Lencesova, Lucia Csaderova, Olga Krizanova, Jana Markova, Sona Hudecova
Publikováno v:
Pflügers Archiv - European Journal of Physiology. 466:1329-1342
Hydrogen sulfide (H2S) as a novel gasotransmitter regulates variety of processes, including calcium transport systems. Sodium calcium exchanger (NCX) is one of the key players in a regulation calcium homeostasis. Thus, the aims of our work were to de
Autor:
Sona Hudecova, Alessio Giubellino, Olga Krizanova, Marta Sirova, Lucia Csaderova, Lubomira Lencesova, Karel Pacak, Marcela Laukova
Publikováno v:
International Journal of Cancer. 131:2445-2455
Pheochromocytomas (PHEOs) and paragangliomas (PGLs) are specific types of neuroendocrine tumors that originate in the adrenal medulla or sympathetic/parasympathetic paraganglia, respectively. Although these tumors are intensively studied, a very effe
Autor:
Marta Sirova, Lubomira Lencesova, Zdena Sulova, Richard Kvetnansky, Lucia Csaderova, Olga Krizanova, Marcela Laukova
Publikováno v:
Neurochemistry International. 57:884-892
The present study addresses the hypothesis that adrenergic regulation modulates the effect of apoptosis. Therefore we studied, whether α1-adrenergic receptor's agonist phenylephrine (PE) can affect or induce apoptosis in rat pheochromocytoma (PC12)
Autor:
A Drgova, Sona Hudecova, Dana Jurkovicova, Peter Racay, Jan Lehotsky, Olga Krizanova, Dusan Dobrota, Peter Kaplan, Eva Babusikova, Marta Sirova
Publikováno v:
Molecular and Cellular Biochemistry. 301:219-226
Aging process is accompanied by various biological dysfunctions including altered calcium homeostasis. Modified calcium handling might be responsible for changed cardiac function and potential development of the pathological state. In the present stu
Autor:
Sona Hudecova, Jana Markova, Michal Pastorek, Dana Cholujova, Marta Sirova, Jan Sedlak, Paulina Gronesova, Veronika Simko, Olga Krizanova, Lucia Csaderova, Silvia Pastorekova, Juraj Kopacek
Publikováno v:
Nitric Oxide. 47:S29-S30
Autor:
Lucia Csaderova, Olga Krizanova, Martin Cagala, Juraj Kopacek, Dana Cholujova, Marta Sirova, Dusan Dobrota, Silvia Pastorekova, Lubomira Lencesova, Sona Hudecova
Publikováno v:
General physiology and biophysics. 30(2)
Up to now a little is known about the effect of hypoxia on the sodium calcium exchanger type 1 (NCX1) expression and function. Therefore, we studied how dimethyloxallyl glycine (DMOG), an activator and stabilizer of the hypoxia-inducible factor (HIF)
Autor:
Martina Labudova, Marta Sirova, Olga Krizanova, Lubomira Lencesova, Karol Ondrias, Silvia Pastorekova, Juraj Kopacek
Publikováno v:
Journal of cellular physiology. 226(12)
Inositol 1,4,5-trisphosphate (IP3) receptors are emerging as key sites for regulation by pro- and anti-apoptotic factors. Induction of apoptosis for 3 h increased mRNA and protein levels of type 1 IP3 receptors in non-differentiated (ND), but not in
Publikováno v:
General physiology and biophysics. 29(4)
Numerous ligands of sigma receptors are known to prolong the QT interval and therefore cause a variety of arrhythmias. High affinity binding sites for the prototypical sigma ligand haloperidol were found in membranes of cardiac myocytes from adult ra