Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Marta Schips"'
Autor:
Mikhail Lebedin, Christoph Ratswohl, Amar Garg, Marta Schips, Clara Vázquez García, Lisa Spatt, Charlotte Thibeault, Benedikt Obermayer, January Weiner, 3rd, Ilais Moreno Velásquez, Cathrin Gerhard, Paula Stubbemann, Leif-Gunnar Hanitsch, Tobias Pischon, Martin Witzenrath, Leif Erik Sander, Florian Kurth, Michael Meyer-Hermann, Kathrin de la Rosa
Publikováno v:
iScience, Vol 27, Iss 3, Pp 109330- (2024)
Summary: Identifying immune modulators that impact neutralizing antibody responses against severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) is of great relevance. We postulated that high serum concentrations of soluble angiotensin-co
Externí odkaz:
https://doaj.org/article/7c9c5701df2748eb9bb1238451f24137
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
The selection of high-affinity B cells and the production of high-affinity antibodies are mediated by T follicular helper cells (Tfhs) within germinal centres (GCs). Therein, somatic hypermutation and selection enhance B cell affinity but risk the em
Externí odkaz:
https://doaj.org/article/f2bf46eedb59447aba06618911ecd49a
Autor:
Arnab Bandyopadhyay, Marta Schips, Tanmay Mitra, Sahamoddin Khailaie, Sebastian C. Binder, Michael Meyer-Hermann
Publikováno v:
Communications Medicine, Vol 2, Iss 1, Pp 1-16 (2022)
Bandyopadhyay, Schips et al. model the factors contributing to overloading of healthcare facilities during the first COVID-19 wave in Italy. They predict that an early test and isolate intervention could have reduced healthcare usage and death rates
Externí odkaz:
https://doaj.org/article/0711f04ebb7f4d7ca6b5a3387bda26c9
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
A variety of B cell clones seed the germinal centers, where a selection stringency expands the fitter clones to generate higher affinity antibodies. However, recent experiments suggest that germinal centers often retain a diverse set of B cell clones
Externí odkaz:
https://doaj.org/article/7b289a69dfb44511a42e79358b2aa7ae
Autor:
Sahamoddin Khailaie, Tanmay Mitra, Arnab Bandyopadhyay, Marta Schips, Pietro Mascheroni, Patrizio Vanella, Berit Lange, Sebastian C. Binder, Michael Meyer-Hermann
Publikováno v:
BMC Medicine, Vol 19, Iss 1, Pp 1-16 (2021)
Abstract Background SARS-CoV-2 has induced a worldwide pandemic and subsequent non-pharmaceutical interventions (NPIs) to control the spread of the virus. As in many countries, the SARS-CoV-2 pandemic in Germany has led to a consecutive roll-out of d
Externí odkaz:
https://doaj.org/article/55faa233bcb8457d90d45e9942f01208
A variety of B cell clones seed the germinal centers, where a selection stringency expands the fitter clones to generate higher affinity antibodies. However, recent experiments suggest that germinal centers often retain a diverse set of B cell clones
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::327b68331f978d656ba028c13db766b1
https://doi.org/10.1101/2022.10.26.513835
https://doi.org/10.1101/2022.10.26.513835
Autor:
Barbara Falkensammer, Michael Meyer-Hermann, Sebastian Binder, Janine Kimpel, Mrinalini Ranjan, Wegene Borena, Lydia Riepler, Katie Bates, Lisa Pipperger, Tanmay Mitra, Ludwig Knabl, Arnab Bandyopadhyay, Dorothee von Laer, André Volland, Annika Rössler, Andreas Walser, Hanno Ulmer, Marta Schips
Publikováno v:
Communications Medicine
Communications medicine
England
Communications medicine
England
Background In early March 2020, a SARS-CoV-2 outbreak in the ski resort Ischgl in Austria initiated the spread of SARS-CoV-2 throughout Austria and Northern Europe. Methods Between April 21st and 27th 2020, a cross-sectional epidemiologic study targe
Autor:
Patrizio Vanella, Sahamoddin Khailaie, Arnab Bandyopadhyay, Tanmay Mitra, Sebastian Binder, Michael Meyer-Hermann, Marta Schips, Berit Lange, Pietro Mascheroni
Publikováno v:
BMC medicine
International
England
BMC Medicine, Vol 19, Iss 1, Pp 1-16 (2021)
BMC Medicine
International
England
BMC Medicine, Vol 19, Iss 1, Pp 1-16 (2021)
BMC Medicine
BackgroundSARS-CoV-2 has induced a worldwide pandemic and subsequent non-pharmaceutical interventions (NPIs) to control the spread of the virus. As in many countries, the SARS-CoV-2 pandemic in Germany has led to a consecutive roll-out of different N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35acecbee65cafadea8fb76e128f9847
https://hdl.handle.net/10033/622727
https://hdl.handle.net/10033/622727
Autor:
Marta Schips, Rinako Nakagawa, Probir Chakravarty, Dinis Pedro Calado, Miriam Llorian-Sopena, Michael Meyer-Hermann, Leena Bhaw-Rosun, Amparo Toboso-Navasa, George Kassiotis, Abdul Sesay, George R. Young
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
United Kingdom
United States
Proceedings of the National Academy of Sciences
United Kingdom
United States
Proceedings of the National Academy of Sciences
Significance Light zone (LZ) B cells are selected in germinal centers (GCs) in a cMyc-dependent manner, before dark zone (DZ) migration. Antigen affinity of B cells is enhanced during GC responses, and some differentiate into plasmablasts or memory B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e324884fd15e41e7bb5e55c4fbb7cd61
https://hdl.handle.net/10033/622718
https://hdl.handle.net/10033/622718
Autor:
Alex K. Shalek, Alejo Efeyan, Juhee Pae, Samuel J. Allon, Coraline Mlynarczyk, Jonatan Ersching, Jose Ordovas-Montanes, Ari Melnick, Gabriel D. Victora, Michael Meyer-Hermann, Marta Schips, Tiago B. R. Castro, Luka Mesin
Publikováno v:
The Journal of experimental medicine
United States
Journal of Experimental Medicine
The Journal of Experimental Medicine
United States
Journal of Experimental Medicine
The Journal of Experimental Medicine
Cyclin D3 drives a unique form of “inertial” cell cycling responsible for clonal expansion of B cells in the germinal center dark zone.
During affinity maturation, germinal center (GC) B cells alternate between proliferation and somatic hype
During affinity maturation, germinal center (GC) B cells alternate between proliferation and somatic hype
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::349c1b82ba66d093d98c507936ef5ec0
https://hdl.handle.net/10033/622666
https://hdl.handle.net/10033/622666