Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Marta Sánchez-Delgado"'
Autor:
Ana Monteagudo-Sánchez, Marta Sánchez-Delgado, Jose Ramon Hernandez Mora, Nuria Tubío Santamaría, Eduard Gratacós, Manel Esteller, Miguel López de Heredia, Virgina Nunes, Cecile Choux, Patricia Fauque, Guiomar Perez de Nanclares, Lauren Anton, Michal A. Elovitz, Isabel Iglesias-Platas, David Monk
Publikováno v:
Clinical Epigenetics, Vol 11, Iss 1, Pp 1-15 (2019)
Abstract Background Genome-wide studies have begun to link subtle variations in both allelic DNA methylation and parent-of-origin genetic effects with early development. Numerous reports have highlighted that the placenta plays a critical role in coo
Externí odkaz:
https://doaj.org/article/9d5ca46d9ac84d09bb6127d3c0d24f71
Autor:
Montserrat Milà, David Monk, Francisco Martínez, Zeynep Tümer, Marta Sánchez Delgado, Cristina Camprubí
Publikováno v:
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 165:472-478
The phenotype overlap between autism spectrum disorders (ASD) & intellectual disabilities (ID) is mirrored at the genetic level, with common genes being reported mutated in variety of developmental disabilities. However despite widespread genetic scr
Autor:
Cécile Choux, Paolo Petazzi, Marta Sanchez-Delgado, José R. Hernandez Mora, Ana Monteagudo, Paul Sagot, David Monk, Patricia Fauque
Publikováno v:
Epigenetics, Vol 15, Iss 12, Pp 1386-1395 (2020)
Although more and more children are born by Assisted Reproductive Technologies (ART), ART safety has not fully been demonstrated. Notably, ART could disturb the delicate step of implantation, and trigger placenta-related adverse outcomes with potenti
Externí odkaz:
https://doaj.org/article/0119378be6004206a04142670873990a
Autor:
Jose Ramon Hernandez Mora, Marta Sanchez-Delgado, Paolo Petazzi, Sebastian Moran, Manel Esteller, Isabel Iglesias-Platas, David Monk
Publikováno v:
Epigenetics, Vol 13, Iss 2, Pp 182-191 (2018)
DNA methylation (5-methylcytosine, 5 mC) is involved in many cellular processes and is an epigenetic mechanism primarily associated with transcriptional repression. The recent discovery that 5 mC can be oxidized to 5-hydromethylcytosine (5hmC) by TET
Externí odkaz:
https://doaj.org/article/767d97737efe4c919fa64ad2c3769e53
Autor:
Alex Martin-Trujillo, Enrique Vidal, Ana Monteagudo-Sánchez, Marta Sanchez-Delgado, Sebastian Moran, Jose Ramon Hernandez Mora, Holger Heyn, Miriam Guitart, Manel Esteller, David Monk
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Altered genomic imprinting is frequently reported in cancer. Here, the authors analyze copy number and methylation in cancer cell lines and primary tumors to show that imprinted methylation profiles represent the accumulation of copy number alteratio
Externí odkaz:
https://doaj.org/article/0ced9395b01e4ea4b12aeea8da2c0e0e
Autor:
Marta Sanchez-Delgado, Franck Court, Enrique Vidal, Jose Medrano, Ana Monteagudo-Sánchez, Alex Martin-Trujillo, Chiharu Tayama, Isabel Iglesias-Platas, Ivanela Kondova, Ronald Bontrop, Maria Eugenia Poo-Llanillo, Tomas Marques-Bonet, Kazuhiko Nakabayashi, Carlos Simón, David Monk
Publikováno v:
PLoS Genetics, Vol 12, Iss 11, p e1006427 (2016)
Thousands of regions in gametes have opposing methylation profiles that are largely resolved during the post-fertilization epigenetic reprogramming. However some specific sequences associated with imprinted loci survive this demethylation process. He
Externí odkaz:
https://doaj.org/article/0e4b89b8a6004bec95c52f9a1c7cafd9
Autor:
Marta Sanchez-Delgado, Alejandro Martin-Trujillo, Chiharu Tayama, Enrique Vidal, Manel Esteller, Isabel Iglesias-Platas, Nandita Deo, Olivia Barney, Ken Maclean, Kenichiro Hata, Kazuhiko Nakabayashi, Rosemary Fisher, David Monk
Publikováno v:
PLoS Genetics, Vol 11, Iss 11, p e1005644 (2015)
Familial recurrent hydatidiform mole (RHM) is a maternal-effect autosomal recessive disorder usually associated with mutations of the NLRP7 gene. It is characterized by HM with excessive trophoblastic proliferation, which mimics the appearance of and
Externí odkaz:
https://doaj.org/article/a46682f4514d4245b4fde6c861e0373a