Výsledky vyhledávání - "Marta Prygiel"

Akademický článek

Challenges of Diphtheria Toxin Detection

Autor: Marta Prygiel, Ewa Mosiej, Maciej Polak, Katarzyna Krysztopa-Grzybowska, Karol Wdowiak, Kamila Formińska, Aleksandra A. Zasada

Publikováno v: Toxins, Vol 16, Iss 6, p 245 (2024)

Diphtheria toxin (DT) is the main virulence factor of Corynebacterium diphtheriae, C. ulcerans and C. pseudotuberculosis. Moreover, new Corynebacterium species with the potential to produce diphtheria toxin have also been described. Therefore, the de

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Akademický článek

Novel combinatorial therapy of oncolytic adenovirus AdV5/3-D24-ICOSL-CD40L with anti PD-1 exhibits enhanced anti-cancer efficacy through promotion of intratumoral T-cell infiltration and modulation of tumour microenvironment in mesothelioma mouse model

Autor: Mariangela Garofalo, Magdalena Wieczorek, Ines Anders, Monika Staniszewska, Michal Lazniewski, Marta Prygiel, Aleksandra Anna Zasada, Teresa Szczepińska, Dariusz Plewczynski, Stefano Salmaso, Paolo Caliceti, Vincenzo Cerullo, Ramon Alemany, Beate Rinner, Katarzyna Pancer, Lukasz Kuryk

Publikováno v: Frontiers in Oncology, Vol 13 (2023)

IntroductionMalignant mesothelioma is a rare and aggressive form of cancer. Despite improvements in cancer treatment, there are still no curative treatment modalities for advanced stage of the malignancy. The aim of this study was to evaluate the ant

Externí odkaz: https://doaj.org/article/7aa8e45e1b514cb0a739223e07f1bcad

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Akademický článek

Adjuvant Effect of Whole-Cell Pertussis Component on Tetanus Toxoid Potency in Murine Model

Autor: Marta Prygiel, Ewa Mosiej, Karol Wdowiak, Daniel Rabczenko, Aleksandra Anna Zasada

Publikováno v: Biomedicines, Vol 11, Iss 7, p 1795 (2023)

There is currently an increasing interest in the development of new-generation purified antigen-based vaccines with a higher safety profile compared to conventional inactivated vaccines. The main problem of subunit vaccines is their lower immunogenic

Externí odkaz: https://doaj.org/article/31a9563481394f569bbcc83d8f7cb9aa

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Akademický článek

Application of loop-mediated isothermal amplification combined with colorimetric and lateral flow dipstick visualization as the potential point-of-care testing for Corynebacterium diphtheriae

Autor: Aleksandra A. Zasada, Aldona Wiatrzyk, Urszula Czajka, Klaudia Brodzik, Kamila Formińska, Ewa Mosiej, Marta Prygiel, Katarzyna Krysztopa-Grzybowska, Karol Wdowiak

Publikováno v: BMC Infectious Diseases, Vol 20, Iss 1, Pp 1-9 (2020)

Abstract Background Diphtheria outbreaks occurred in endemic areas and imported and indigenous cases are reported in UE/EEA. Because of the high infectiveness and severity of the disease, early and accurate diagnosis of each suspected case is essenti

Externí odkaz: https://doaj.org/article/d70f250288b74b4791807ac8d42768fd

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Akademický článek

New Corynebacterium Species with the Potential to Produce Diphtheria Toxin

Autor: Marta Prygiel, Maciej Polak, Ewa Mosiej, Karol Wdowiak, Kamila Formińska, Aleksandra Anna Zasada

Publikováno v: Pathogens, Vol 11, Iss 11, p 1264 (2022)

Only three Corynebacterium species are known to produce a lethal exotoxin called diphtheria toxin. These are C. diphtheriae, C. ulcerans and C. pseudotuberculosis. The diphtheria toxin gene (tox) is carried in a family of closely related corynebacter

Externí odkaz: https://doaj.org/article/d58f2aee38bb4ac798c5650682e83508

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Akademický článek

Detection of SARS-CoV-2 Using Reverse Transcription Helicase Dependent Amplification and Reverse Transcription Loop-Mediated Amplification Combined with Lateral Flow Assay

Autor: Aleksandra Anna Zasada, Ewa Mosiej, Marta Prygiel, Maciej Polak, Karol Wdowiak, Kamila Formińska, Robert Ziółkowski, Kamil Żukowski, Kasper Marchlewicz, Adam Nowiński, Julia Nowińska, Waldemar Rastawicki, Elżbieta Malinowska

Publikováno v: Biomedicines, Vol 10, Iss 9, p 2329 (2022)

Rapid and accurate detection and identification of pathogens in clinical samples is essential for all infection diseases. However, in the case of epidemics, it plays a key role not only in the implementation of effective therapy but also in limiting

Externí odkaz: https://doaj.org/article/9601071bbc85410e9934846b44a3e9c3

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