Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Marta Pozniak"'
Autor:
Aleksandra Gedaj, Dominika Zukowska, Natalia Porebska, Marta Pozniak, Mateusz Krzyscik, Aleksandra Czyrek, Daniel Krowarsch, Malgorzata Zakrzewska, Jacek Otlewski, Lukasz Opalinski
Publikováno v:
Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-12 (2023)
Abstract Fibroblast growth factors (FGFs) and their receptors (FGFRs) constitute complex signaling hubs that are crucial for the development and homeostasis of the human body. Most of FGFs are released by cells using the conventional secretory pathwa
Externí odkaz:
https://doaj.org/article/5369028b02574eedbb75af36e1e6b04b
Autor:
Aleksandra Gedaj, Dominika Zukowska, Natalia Porebska, Marta Pozniak, Mateusz Krzyscik, Aleksandra Czyrek, Daniel Krowarsch, Malgorzata Zakrzewska, Jacek Otlewski, Lukasz Opalinski
Publikováno v:
Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/4263889e564240a8a62044afc630546c
Autor:
Marta Pozniak, Aleksandra Sokolowska‐Wedzina, Kamil Jastrzebski, Jakub Szymczyk, Natalia Porebska, Mateusz Adam Krzyscik, Malgorzata Zakrzewska, Marta Miaczynska, Jacek Otlewski, Lukasz Opalinski
Publikováno v:
Molecular Oncology, Vol 14, Iss 9, Pp 1998-2021 (2020)
Fibroblast growth factor receptor 1 (FGFR1) transmits signals through the plasma membrane regulating essential cellular processes like division, motility, metabolism, and death. Overexpression of FGFR1 is observed in numerous tumors and thus constitu
Externí odkaz:
https://doaj.org/article/41add822f32c4099b544103cf1062b2c
Autor:
Aleksandra Gedaj, Dominika Zukowska, Natalia Porebska, Marta Pozniak, Mateusz Krzyscik, Aleksandra Czyrek, Daniel Krowarsch, Malgorzata Zakrzewska, Jacek Otlewski, Lukasz Opalinski
Publikováno v:
Cell Communication and Signaling. 21
Fibroblast growth factors (FGFs) and their receptors (FGFRs) constitute complex signaling hubs that are crucial for the development and homeostasis of the human body. Most of FGFs are released by cells using the conventional secretory pathway and are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5d94b96d1d916d40e69b59c0c798b0ec
https://doi.org/10.1186/s12964-023-01144-x
https://doi.org/10.1186/s12964-023-01144-x
Autor:
Dominika Zukowska, Aleksandra Gedaj, Natalia Porebska, Marta Pozniak, Mateusz Krzyscik, Aleksandra Czyrek, Daniel Krowarsch, Malgorzata Zakrzewska, Jacek Otlewski, Lukasz Opalinski
Publikováno v:
Cellular and Molecular Life Sciences. 80
FGF/FGFR signaling is critical for the development and homeostasis of the human body and imbalanced FGF/FGFR contributes to the progression of severe diseases, including cancers. FGFRs are N-glycosylated, but the role of these modifications is largel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b447bdf7408416a93aee23148e06718b
https://doi.org/10.1007/s00018-023-04768-x
https://doi.org/10.1007/s00018-023-04768-x
Autor:
Natalia Porębska, Marika Kucińska, Malgorzata Zakrzewska, Marta Pozniak, Lukasz Opalinski, Jacek Otlewski, Mateusz Adam Krzyscik, Agata Knapik, Aleksandra Czyrek, Kamil Jastrzębski
Publikováno v:
International Journal of Biological Macromolecules. 180:470-483
Fibroblast growth factor receptors (FGFRs) are integral membrane proteins involved in various biological processes including proliferation, migration and apoptosis. There are a number of regulatory mechanisms of FGFR signaling, which tightly control
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4be9a349649da4357e59be77150199f3
https://doi.org/10.1016/j.ijbiomac.2021.03.094
https://doi.org/10.1016/j.ijbiomac.2021.03.094
Autor:
Dominika Żukowska, Aleksandra Chorążewska, Krzysztof Ciura, Aleksandra Gędaj, Marta Kalka, Marta Poźniak, Natalia Porębska, Łukasz Opaliński
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-19 (2024)
Abstract Fibroblast growth factor receptor 1 (FGFR1) is a N-glycosylated cell surface receptor tyrosine kinase, which upon recognition of specific extracellular ligands, fibroblast growth factors (FGFs), initiates an intracellular signaling. FGFR1 si
Externí odkaz:
https://doaj.org/article/65935c36d3104f28b101dad5fb8822b0
Autor:
Daria Nawrocka, Aleksandra Sokolowska-Wedzina, Karolina Jendryczko, Mateusz Adam Krzyscik, Natalia Porębska, Marta Pozniak, Malgorzata Zakrzewska, Lukasz Opalinski, Jacek Otlewski, Anna Szlachcic
Publikováno v:
Journal of Visualized Experiments.
Cancer is currently the second most common cause of death worldwide. The hallmark of cancer cells is the presence of specific marker proteins such as growth factor receptors on their surface. This feature enables development of highly selective thera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dc5a9e6cdae65d48d0fa9f5cab41080
https://doi.org/10.3791/61918
https://doi.org/10.3791/61918
Autor:
Marta Poźniak, Natalia Porębska, Kamil Jastrzębski, Mateusz Adam Krzyścik, Marika Kucińska, Weronika Zarzycka, Agnieszka Barbach, Małgorzata Zakrzewska, Jacek Otlewski, Marta Miączyńska, Łukasz Opaliński
Publikováno v:
Journal of Biomedical Science, Vol 28, Iss 1, Pp 1-21 (2021)
Abstract Background Overexpression of FGFR1 is observed in numerous tumors and therefore this receptor constitutes an attractive molecular target for selective cancer treatment with cytotoxic conjugates. The success of cancer therapy with cytotoxic c
Externí odkaz:
https://doaj.org/article/62043f3c34124fccac65d60cd456bc98
Autor:
Marta Poźniak, Natalia Porębska, Mateusz Adam Krzyścik, Aleksandra Sokołowska-Wędzina, Kamil Jastrzębski, Martyna Sochacka, Jakub Szymczyk, Małgorzata Zakrzewska, Jacek Otlewski, Łukasz Opaliński
Publikováno v:
Molecular Medicine, Vol 27, Iss 1, Pp 1-13 (2021)
Abstract Background Antibody drug conjugates (ADCs) represent one of the most promising approaches in the current immuno-oncology research. The precise delivery of cytotoxic drugs to the cancer cells using ADCs specific for tumor-associated antigens
Externí odkaz:
https://doaj.org/article/9140866be0fd45268595cc52c24c3f7b