Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Marta Poźniak"'
Autor:
Dominika Żukowska, Aleksandra Chorążewska, Krzysztof Ciura, Aleksandra Gędaj, Marta Kalka, Marta Poźniak, Natalia Porębska, Łukasz Opaliński
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-19 (2024)
Abstract Fibroblast growth factor receptor 1 (FGFR1) is a N-glycosylated cell surface receptor tyrosine kinase, which upon recognition of specific extracellular ligands, fibroblast growth factors (FGFs), initiates an intracellular signaling. FGFR1 si
Externí odkaz:
https://doaj.org/article/65935c36d3104f28b101dad5fb8822b0
Autor:
Marta Poźniak, Natalia Porębska, Kamil Jastrzębski, Mateusz Adam Krzyścik, Marika Kucińska, Weronika Zarzycka, Agnieszka Barbach, Małgorzata Zakrzewska, Jacek Otlewski, Marta Miączyńska, Łukasz Opaliński
Publikováno v:
Journal of Biomedical Science, Vol 28, Iss 1, Pp 1-21 (2021)
Abstract Background Overexpression of FGFR1 is observed in numerous tumors and therefore this receptor constitutes an attractive molecular target for selective cancer treatment with cytotoxic conjugates. The success of cancer therapy with cytotoxic c
Externí odkaz:
https://doaj.org/article/62043f3c34124fccac65d60cd456bc98
Autor:
Marta Poźniak, Natalia Porębska, Mateusz Adam Krzyścik, Aleksandra Sokołowska-Wędzina, Kamil Jastrzębski, Martyna Sochacka, Jakub Szymczyk, Małgorzata Zakrzewska, Jacek Otlewski, Łukasz Opaliński
Publikováno v:
Molecular Medicine, Vol 27, Iss 1, Pp 1-13 (2021)
Abstract Background Antibody drug conjugates (ADCs) represent one of the most promising approaches in the current immuno-oncology research. The precise delivery of cytotoxic drugs to the cancer cells using ADCs specific for tumor-associated antigens
Externí odkaz:
https://doaj.org/article/9140866be0fd45268595cc52c24c3f7b
Autor:
Marta Poźniak, Dominika Żukowska, Aleksandra Gędaj, Mateusz Adam Krzyścik, Natalia Porębska, Małgorzata Zakrzewska, Jacek Otlewski, Łukasz Opaliński
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 15, p 8514 (2022)
Precise anticancer therapies employing cytotoxic conjugates constitute a side-effect-limited, highly attractive alternative to commonly used cancer treatment modalities, such as conventional chemotherapy, radiotherapy or surgical interventions. Recep
Externí odkaz:
https://doaj.org/article/5f5f6b7264f942bfb061fe511ef5aae2
Autor:
Marta Poźniak, Weronika Zarzycka, Natalia Porębska, Agata Knapik, Paulina Marczakiewicz-Perera, Malgorzata Zakrzewska, Jacek Otlewski, Łukasz Opaliński
Publikováno v:
Biomolecules, Vol 11, Iss 8, p 1088 (2021)
FGFRs are cell surface receptors that, when activated by specific FGFs ligands, transmit signals through the plasma membrane, regulating key cellular processes such as differentiation, division, motility, metabolism and death. We have recently shown
Externí odkaz:
https://doaj.org/article/e24828ebb36049e88ad5cdbeb56eb2cd
Autor:
Łukasz Opaliński, Natalia Porębska, Mateusz Adam Krzyścik, Agata Knapik, Malgorzata Zakrzewska, Jacek Otlewski, Marta Poźniak
Publikováno v:
Biomacromolecules
Fibroblast growth factor receptor 1 (FGFR1) is an integral membrane protein that transmits prolife signals through the plasma membrane. Overexpression of FGFR1 has been reported in various tumor types, and therefore, this receptor constitutes an attr
Autor:
Marta Poźniak, Aleksandra Matynia, Malgorzata Zakrzewska, Jacek Otlewski, Dominika Żukowska, Natalia Porębska, Łukasz Opaliński
Publikováno v:
Cytokine & Growth Factor Reviews. 60:89-106
Receptor tyrosine kinases (RTKs) constitute a large group of cell surface proteins that mediate communication of cells with extracellular environment. RTKs recognize external signals and transfer information to the cell interior, modulating key cellu
Autor:
Mateusz Adam Krzyścik, Marta Poźniak, Agnieszka Barbach, Marika Kucińska, Malgorzata Zakrzewska, Kamil Jastrzębski, Weronika Zarzycka, Marta Miączyńska, Natalia Porębska, Jacek Otlewski, Łukasz Opaliński
Publikováno v:
Journal of Biomedical Science
Journal of Biomedical Science, Vol 28, Iss 1, Pp 1-21 (2021)
Journal of Biomedical Science, Vol 28, Iss 1, Pp 1-21 (2021)
Background Overexpression of FGFR1 is observed in numerous tumors and therefore this receptor constitutes an attractive molecular target for selective cancer treatment with cytotoxic conjugates. The success of cancer therapy with cytotoxic conjugates
Autor:
Łukasz Opaliński, Jacek Otlewski, Agata Knapik, Natalia Porębska, Malgorzata Zakrzewska, Weronika Zarzycka, Paulina Marczakiewicz-Perera, Marta Poźniak
Publikováno v:
Biomolecules
Volume 11
Issue 8
Biomolecules, Vol 11, Iss 1088, p 1088 (2021)
Volume 11
Issue 8
Biomolecules, Vol 11, Iss 1088, p 1088 (2021)
FGFRs are cell surface receptors that, when activated by specific FGFs ligands, transmit signals through the plasma membrane, regulating key cellular processes such as differentiation, division, motility, metabolism and death. We have recently shown
Autor:
Mateusz Adam Krzyścik, Marta Poźniak, Łukasz Opaliński, Natalia Porębska, Martyna Sochacka, Jakub Szymczyk, Kamil Jastrzębski, Aleksandra Sokolowska-Wedzina, Malgorzata Zakrzewska, Jacek Otlewski
Publikováno v:
Molecular Medicine
Molecular Medicine, Vol 27, Iss 1, Pp 1-13 (2021)
Molecular Medicine, Vol 27, Iss 1, Pp 1-13 (2021)
Background Antibody drug conjugates (ADCs) represent one of the most promising approaches in the current immuno-oncology research. The precise delivery of cytotoxic drugs to the cancer cells using ADCs specific for tumor-associated antigens enables s