Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Marta Murgia"'
Autor:
Marta Murgia, Jörn Rittweger, Carlo Reggiani, Roberto Bottinelli, Matthias Mann, Stefano Schiaffino, Marco V. Narici
Publikováno v:
npj Microgravity, Vol 10, Iss 1, Pp 1-13 (2024)
Abstract Skeletal muscle undergoes atrophy and loss of force during long space missions, when astronauts are persistently exposed to altered gravity and increased ionizing radiation. We previously carried out mass spectrometry-based proteomics from s
Externí odkaz:
https://doaj.org/article/d9da0d2913eb400aba4ff0b6bd8d8af9
Autor:
Serge Ducommun, Paulo R. Jannig, Igor Cervenka, Marta Murgia, Melanie J. Mittenbühler, Ekaterina Chernogubova, José M. Dias, Baptiste Jude, Jorge C. Correia, Jonathan G. Van Vranken, Gabriel Ocana-Santero, Margareta Porsmyr-Palmertz, Sarah McCann Haworth, Vicente Martínez-Redondo, Zhengye Liu, Mattias Carlström, Matthias Mann, Johanna T. Lanner, Ana I. Teixeira, Lars Maegdefessel, Bruce M. Spiegelman, Jorge L. Ruas
Publikováno v:
Molecular Metabolism, Vol 82, Iss , Pp 101912- (2024)
Objective: Skeletal muscle plasticity and remodeling are critical for adapting tissue function to use, disuse, and regeneration. The aim of this study was to identify genes and molecular pathways that regulate the transition from atrophy to compensat
Externí odkaz:
https://doaj.org/article/2abd30b26178418fbe5ccf30fb438f44
Autor:
Marta Murgia, Lorenza Brocca, Elena Monti, Martino V. Franchi, Maximilian Zwiebel, Sophia Steigerwald, Emiliana Giacomello, Roberta Sartori, Sandra Zampieri, Giovanni Capovilla, Mladen Gasparini, Gianni Biolo, Marco Sandri, Matthias Mann, Marco V. Narici
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 14, Iss 1, Pp 439-451 (2023)
Abstract Background Inactivity and unloading induce skeletal muscle atrophy, loss of strength and detrimental metabolic effects. Bed rest is a model to study the impact of inactivity on the musculoskeletal system. It not only provides information for
Externí odkaz:
https://doaj.org/article/9d9b8bbf22f641feb6b345de3ca07c32
Autor:
Marta Murgia, Leonardo Nogara, Martina Baraldo, Carlo Reggiani, Matthias Mann, Stefano Schiaffino
Publikováno v:
Skeletal Muscle, Vol 11, Iss 1, Pp 1-19 (2021)
Abstract Background Human skeletal muscle is composed of three major fiber types, referred to as type 1, 2A, and 2X fibers. This heterogeneous cellular composition complicates the interpretation of studies based on whole skeletal muscle lysate. A sin
Externí odkaz:
https://doaj.org/article/9a2d90d6736b4e079c06502c1b989d35
Autor:
Yanxin Fan, Marta Murgia, Monika I. Linder, Yoko Mizoguchi, Cong Wang, Marcin Łyszkiewicz, Natalia Ziȩtara, Yanshan Liu, Stephanie Frenz, Gabriela Sciuccati, Armando Partida-Gaytan, Zahra Alizadeh, Nima Rezaei, Peter Rehling, Sven Dennerlein, Matthias Mann, Christoph Klein
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 9 (2022)
The relevance of molecular mechanisms governing mitochondrial proteostasis to the differentiation and function of hematopoietic and immune cells is largely elusive. Through dissection of the network of proteins related to HCLS1-associated protein X-1
Externí odkaz:
https://doaj.org/article/48d4a94c9494431abcad847db209c4a5
Autor:
Mohammad Zulkifli, John K. Neff, Shrishiv A. Timbalia, Natalie M. Garza, Yingqi Chen, Jeramie D. Watrous, Marta Murgia, Prachi P. Trivedi, Steven K. Anderson, Dhanendra Tomar, Roland Nilsson, Muniswamy Madesh, Mohit Jain, Vishal M. Gohil
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Although some fungal mitochondria lack the calcium uniporter, many intriguingly encode homologs of the uniporter assembly factor MCUR1. Here, the authors show that in budding yeast, the MCUR1 homologs Put6 and Put7 regulate mitochondrial proline meta
Externí odkaz:
https://doaj.org/article/389bd4b04d3b4af58e574df071abb507
Autor:
Gabryela Kuhnen, Tiago Guedes Russomanno, Marta Murgia, Nicolas J. Pillon, Martin Schönfelder, Henning Wackerhage
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 21, p 12933 (2022)
Adult skeletal muscle fibres are classified as type 1, 2A, 2X, and 2B. These classifications are based on the expression of the dominant myosin heavy chain isoform. Muscle fibre-specific gene expression and proportions of muscle fibre types change du
Externí odkaz:
https://doaj.org/article/1dbf40b9308f4d34aecae09e5126aae0
Autor:
Sandra Furlan, Marina Campione, Marta Murgia, Simone Mosole, Francesco Argenton, Pompeo Volpe, Alessandra Nori
Publikováno v:
Frontiers in Neuroanatomy, Vol 14 (2020)
Calcium stores in neurons are heterogeneous in compartmentalization and molecular composition. Danio rerio (zebrafish) is an animal model with a simply folded cerebellum similar in cellular organization to that of mammals. The aim of the study was to
Externí odkaz:
https://doaj.org/article/63f3acbfb4ec41e697a19ffda6fff43b
Publikováno v:
Cell Reports, Vol 29, Iss 12, Pp 3825-3834.e4 (2019)
Summary: The mosaic distribution of cytochrome c oxidase+ (COX+) and COX− muscle fibers in mitochondrial disorders allows the sampling of fibers with compensated and decompensated mitochondrial function from the same individual. We apply laser capt
Externí odkaz:
https://doaj.org/article/064c40ef553d4d9698d617080dcbec4f
Autor:
Daniel N. Itzhak, Francesca Sacco, Nagarjuna Nagaraj, Stefka Tyanova, Matthias Mann, Marta Murgia
Publikováno v:
Disease Models & Mechanisms, Vol 12, Iss 11 (2019)
The unfolded protein response (UPR) involves extensive proteome remodeling in many cellular compartments. To date, a comprehensive analysis of the UPR has not been possible because of technological limitations. Here, we employ stable isotope labeling
Externí odkaz:
https://doaj.org/article/ace79d21ea914797bb3163c1d71e5bf9