Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Marta Minguet"'
Autor:
Yin P Hung, Carolyn Teragawa, Nont Kosaisawe, Taryn E Gillies, Michael Pargett, Marta Minguet, Kevin Distor, Briana L Rocha-Gregg, Jonathan L Coloff, Mark A Keibler, Gregory Stephanopoulos, Gary Yellen, Joan S Brugge, John G Albeck
Publikováno v:
eLife, Vol 6 (2017)
Cells use multiple feedback controls to regulate metabolism in response to nutrient and signaling inputs. However, feedback creates the potential for unstable network responses. We examined how concentrations of key metabolites and signaling pathways
Externí odkaz:
https://doaj.org/article/f8f04aa15ba940f9b5b72b1ccab92464
Autor:
Diana Bou-Teen, David Garcia-Dorado, Marta Minguet, Jesús Vázquez, Elena Bonzón-Kulichenko, Celia Castans, Alberto Igual, Rafael Rodriguez-Lecoq, José M. Castellano, Marisol Ruiz-Meana, Elisabet Miró-Casas
Publikováno v:
Circulation. 139(7)
Background: Senescent cardiomyocytes exhibit a mismatch between energy demand and supply that facilitates their transition toward failing cells. Altered calcium transfer from sarcoplasmic reticulum (SR) to mitochondria has been causally linked to the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18f8ddcd16799bd5287fcd9ee70f4fa7
https://pubmed.ncbi.nlm.nih.gov/30586718
https://pubmed.ncbi.nlm.nih.gov/30586718
Publikováno v:
Cancer Research. 75:B2-38
To characterize key cell signaling pathways in cancer, we employ a modular strategy to examine how signals propagate between two members in a pathway, using paired time series measurements in live cells. The two pathway members chosen bracket a sub-n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e4461592b850e2cc95554fc890ae9ba7
https://doi.org/10.1158/1538-7445.compsysbio-b2-38
https://doi.org/10.1158/1538-7445.compsysbio-b2-38
Publikováno v:
Cancer Research. 75:A2-67
Defects in cell-to-cell signaling pathways can result in developmental abnormalities as well as cancer. The Ras/MAPK pathway is a central regulator of gene expression, cellular proliferation, and differentiation that is frequently de-regulated in can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ac1c999789b8ce18a96ba6d343fc4e1
https://doi.org/10.1158/1538-7445.transcagen-a2-67
https://doi.org/10.1158/1538-7445.transcagen-a2-67
Publikováno v:
Cancer Research. 75:B1-30
Receptor tyrosine kinases transduce signals through ERK and drive distinct cellular behaviors, but it is not clear how dynamic patterns of ERK activity are generated. To approach this question quantitatively, we have generated an epithelial cell line
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b246d473c21011c6597cde17e32d0aa0
https://doi.org/10.1158/1538-7445.compsysbio-b1-30
https://doi.org/10.1158/1538-7445.compsysbio-b1-30
Publikováno v:
The Journal of biological chemistry, vol 290, iss 41
In both physiological and cell culture systems, EGF-stimulated ERK activity occurs in discrete pulses within individual cells. Many feedback loops are present in the EGF receptor (EGFR)-ERK network, but the mechanisms driving pulsatile ERK kinetics a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce811599c3040b9d0079acbc8bfb2da9
https://doi.org/10.1074/jbc.m115.662247
https://doi.org/10.1074/jbc.m115.662247
Autor:
Carolyn Teragawa, Mark A. Keibler, Joan S. Brugge, Nont Kosaisawe, Gary Yellen, Michael Pargett, Yin P Hung, Briana L Rocha-Gregg, John G. Albeck, Jonathan L. Coloff, Gregory Stephanopoulos, Kevin Distor, Taryn E. Gillies, Marta Minguet
Publikováno v:
eLife, Vol 6 (2017)
eLife
eLife
Cells use multiple feedback controls to regulate metabolism in response to nutrient and signaling inputs. However, feedback creates the potential for unstable network responses. We examined how concentrations of key metabolites and signaling pathways
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1103a3feed3ef14925b866e66c5c4fc
https://elifesciences.org/articles/27293
https://elifesciences.org/articles/27293
Autor:
Carolyn Teragawa, Kevin Distor, Jonathan L. Coloff, Gregory Stephanopoulos, Nont Kosaisawe, Mark A. Keibler, Gary Yellen, John G. Albeck, Michael Pargett, Briana L Rocha-Gregg, Joan S. Brugge, Yin P Hung, Taryn E. Gillies, Marta Minguet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::43dae2efc5c791855144072e7e7f06b9
https://doi.org/10.7554/elife.27293.038
https://doi.org/10.7554/elife.27293.038
Autor:
Briana L Rocha-Gregg, Carolyn Teragawa, Kevin Distor, Gary Yellen, Michael Pargett, Yin P Hung, Joan S. Brugge, Taryn E. Gillies, Nont Kosaisawe, Marta Minguet, John G. Albeck
Cells use multiple feedback controls to regulate metabolism in response to nutrient and signaling inputs. However, feedback creates the potential for unstable network responses. We examined how concentrations of key metabolites and signaling pathways
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::045e8278b6d9f1a2fdc75c6be492c096
Publikováno v:
Cell Systems. 5:549-563.e5
ERK signaling regulates the expression of target genes, but it is unclear how ERK activity dynamics are interpreted. Here, we investigate this question using simultaneous, live, single-cell imaging of two ERK activity reporters and expression of Fra-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfa759ebeadd5577b08a4ec1ce57c9e6
https://doi.org/10.1016/j.cels.2017.10.019
https://doi.org/10.1016/j.cels.2017.10.019