Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Marta M. Nawrocky"'
Autor:
Marta M. Nawrocky, S. David Smith, Zhongchi Luo, Helene Benveniste, Jasbeer Dhawan, Anat Biegon
Publikováno v:
Future Neurology. 6:823-834
Ischemic stroke triggers a massive, although transient, glutamate efflux and excessive activation of NMDA receptors (NMDARs), possibly leading to neuronal death. However, multiple clinical trials with NMDA antagonists failed to improve, or even worse
Autor:
Joan H. Rotaru, Nilendu Gupta, Jeffrey A. Coderre, Rolf F. Barth, Einar K. Rofstad, Marta M. Nawrocky, Brent J. Albertson, Melvin L. Moeschberger, Amy K. Ferketich, John C. Grecula, Weilan Yang
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 58:267-277
Purpose Boron neutron capture therapy (BNCT) has been used clinically as a single modality treatment for high-grade gliomas and melanomas metastatic to the brain. The purpose of the present study was to determine whether its efficacy could be enhance
Autor:
Marta M. Nawrocky, Raymond T. Bartus, Joan H. Rotaru, Jeffrey A. Coderre, Amy K. Ferketich, Weilian Yang, Melvin L. Moeschberger, Rolf F. Barth, Einar K. Rofstad
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 52:858-868
Purpose : Multicentric cerebral metastases of melanoma represent an important clinical problem for which there currently is no satisfactory treatment. We previously developed a model for melanoma metastatic to the brain employing nude rats bearing in
Autor:
N. Gebbers, Marta M. Nawrocky, Jeffrey A. Coderre, G.H. Jahng, W. Tu, A. Pinkerton, Henry M. Smilowitz, Daniel N. Slatkin
Publikováno v:
Journal of Neuro-Oncology. 57:9-18
Rats with advanced, imminently lethal, ∼4 mm diameter, left-sided intracerebral 9L gliosarcoma (9LGS), a well characterized malignant tumor with some similarities to human high-grade astrocytomas, were used as a therapy model 14 days post-implantat
Autor:
Duane A. Hoch, Peggy L. Micca, Darrel D. Joel, Michiko Miura, Jeffrey A. Coderre, Marta M. Nawrocky, Henry M. Smilowitz, Daniel N. Slatkin
Publikováno v:
Journal of Neuro-Oncology. 52:111-117
The biodistributions of carborane-containing copper porphyrins, CuTCP and CuTCPH, have been studied previously in mice bearing subcutaneously implanted mammary carcinomas. We now report biodistributions of those porphyrins in Fischer 344 rats bearing
Autor:
Rolf F. Barth, Joseph H. Goodman, Raymond T. Bartus, Joan H. Rotaru, Jeffrey A. Coderre, Weilian Yang, Amy K. Ferketich, Melvin L. Moeschberger, Marta M. Nawrocky
Publikováno v:
Neurosurgery. 47:189-198
OBJECTIVE Cereport (Alkermes, Inc., Cambridge, MA), or, as it has been previously called, RMP-7 (receptor-mediated permeabilizer-7), is a bradykinin analog that has been shown to produce a transient, pharmacologically mediated opening of the blood-br
Autor:
Virginia M. Goettl, Jacqueline C. Bresnahan, Carl P. Boesel, Darrel D. Joel, Marie Hadjiconstantinou, David A. Wilkie, Joan H. Rotaru, Rolf F. Barth, Marta M. Nawrocky, Weilian Yang
Publikováno v:
Journal of Neuro-Oncology. 48:179-190
Sodium borocaptate (BSH) and boronophenylalanine (BPA) are two drugs that have been used clinically for boron neutron capture therapy (BNCT) of brain tumors. We previously have reported that hyperosmotic mannitol-induced disruption of the blood–bra
Autor:
W. Tu, Kelly M. Youngs, Daniel N. Slatkin, Marta M. Nawrocky, Darrel D. Joel, Peggy L. Micca, Henry M. Smilowitz, Jeffrey A. Coderre
Publikováno v:
Journal of Neuro-Oncology. 46:193-203
Glioblastoma multiforme (GBM) is the most common primary human brain tumor. About 7000 new cases are diagnosed yearly in the USA. Despite current neurosurgical and postoperative radiotherapeutic tumor cytoreduction methods, in most cases occult foci
Autor:
Peggy L. Micca, W. Tu, Marta M. Nawrocky, Jeffrey A. Coderre, Henry M. Smilowitz, Daniel N. Slatkin
Publikováno v:
Journal of Neuro-Oncology. 46:231-240
Glioblastoma multiforme (GBM) is the most common primary human brain tumor. About 7000 new cases are diagnosed yearly in the USA and GBM is almost invariably fatal within a few years after it is diagnosed. Despite current neurosurgical and radiothera
Autor:
Darrel D. Joel, Michael S. Makar, Marianne Geiser, P. Spanne, F.A. Dilmanian, Peggy L. Micca, Daniel N. Slatkin, X. Y. Wu, G Geiser, J.-O. Gebbers, Jean A. Laissue, Marta M. Nawrocky
Publikováno v:
International Journal of Cancer. 78:654-660
Adult-rat-brain tissues display an unusually high resistance to necrosis when serially irradiated with parallel, thin slices of a microplanar (i.e., microscopically thin and macroscopically broad) beam of synchrotron-wiggler-generated, approx. 35-120