Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Marta Luna-Sánchez"'
Autor:
Emma Puighermanal, Marta Luna-Sánchez, Alejandro Gella, Gunter van der Walt, Andrea Urpi, María Royo, Paula Tena-Morraja, Isabella Appiah, Maria Helena de Donato, Fabien Menardy, Patrizia Bianchi, Anna Esteve-Codina, Laura Rodríguez-Pascau, Cristina Vergara, Mercè Gómez-Pallarès, Giovanni Marsicano, Luigi Bellocchio, Marc Martinell, Elisenda Sanz, Sandra Jurado, Francesc Xavier Soriano, Pilar Pizcueta, Albert Quintana
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract Mutations in mitochondrial energy-producing genes lead to a heterogeneous group of untreatable disorders known as primary mitochondrial diseases (MD). Leigh syndrome (LS) is the most common pediatric MD and is characterized by progressive ne
Externí odkaz:
https://doaj.org/article/622861ac6cc14a5babd24370dd72d435
Autor:
Marta Luna‐Sánchez, Agustín Hidalgo‐Gutiérrez, Tatjana M Hildebrandt, Julio Chaves‐Serrano, Eliana Barriocanal‐Casado, Ángela Santos‐Fandila, Miguel Romero, Ramy KA Sayed, Juan Duarte, Holger Prokisch, Markus Schuelke, Felix Distelmaier, Germaine Escames, Darío Acuña‐Castroviejo, Luis C López
Publikováno v:
EMBO Molecular Medicine, Vol 9, Iss 1, Pp 78-95 (2016)
Abstract Coenzyme Q (CoQ) is a key component of the mitochondrial respiratory chain, but it also has several other functions in the cellular metabolism. One of them is to function as an electron carrier in the reaction catalyzed by sulfide:quinone ox
Externí odkaz:
https://doaj.org/article/cfc05c1d2c8d4810a7dc5eb296a00eff
Autor:
Marta Luna‐Sánchez, Elena Díaz‐Casado, Emanuele Barca, Miguel Ángel Tejada, Ángeles Montilla‐García, Enrique Javier Cobos, Germaine Escames, Dario Acuña‐Castroviejo, Catarina M Quinzii, Luis Carlos López
Publikováno v:
EMBO Molecular Medicine, Vol 7, Iss 5, Pp 670-687 (2015)
Abstract Primary coenzyme Q10 (CoQ10) deficiency is due to mutations in genes involved in CoQ biosynthesis. The disease has been associated with five major phenotypes, but a genotype–phenotype correlation is unclear. Here, we compare two mouse mode
Externí odkaz:
https://doaj.org/article/f4d8987aef6d405389fe3b02b95dd32d
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 8523, p 8523 (2021)
International Journal of Molecular Sciences, Vol 22, Iss 8523, p 8523 (2021)
Funding: This work was supported by a Juan de la Cierva grant (IJC2018-036938-I). A.Q. received funds from the European Research Council (Starting grant NEUROMITO, ERC-2014-StG-638106), MINECO Proyectos I + D de Excelencia (SAF2014-57981P; SAF2017-88
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::964fa20199ba6c4daa5bcf2a480569c3
http://europepmc.org/articles/PMC8395232
http://europepmc.org/articles/PMC8395232
Autor:
Germaine Escames, Holger Prokisch, Darío Acuña-Castroviejo, Juan Duarte, Felix Distelmaier, Marta Luna-Sánchez, Julio Chaves-Serrano, Eliana Barriocanal-Casado, Ángela Santos-Fandila, Tatjana M. Hildebrandt, Miguel Romero, Agustín Hidalgo-Gutiérrez, Luis C. López, Markus Schuelke, Ramy K. A. Sayed
Publikováno v:
EMBO Molecular Medicine
EMBO Molecular Medicine 9 (2017), Nr. 1
EMBO Molecular Medicine 9 (2017), Nr. 1
Coenzyme Q (CoQ) is a key component of the mitochondrial respiratory chain, but it also has several other functions in the cellular metabolism. One of them is to function as an electron carrier in the reaction catalyzed by sulfide:quinone oxidoreduct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5290772cf84b54588fc6e3b5bc90ac82
http://europepmc.org/articles/PMC5210161
http://europepmc.org/articles/PMC5210161
Autor:
María E. Díaz-Casado, Luis C. López, Germaine Escames, Beatriz Fernández-Gil, Carolina Doerrier, Huayqui Volt, Jose A. García, Darío Acuña-Castroviejo, Marta Luna-Sánchez
Publikováno v:
Mitochondrion. 27:56-63
Analysis of mitochondrial function is crucial to understand their involvement in a given disease. High-resolution respirometry of permeabilized myocardial fibers in septic mice allows the evaluation of the bioenergetic system, maintaining mitochondri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11979d200f458a2f5a161e58297a73b1
https://doi.org/10.1016/j.mito.2015.12.010
https://doi.org/10.1016/j.mito.2015.12.010
Autor:
Eliana Barriocanal-Casado, María Rodríguez-Hidalgo, Marta Luna-Sánchez, Germaine Escames, Darío Acuña-Castroviejo, Agustín Hidalgo-Gutiérrez, Margarita Rivera, Cristina Mascaraque, Luis C. López
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Digibug. Repositorio Institucional de la Universidad de Granada
instname
Digibug. Repositorio Institucional de la Universidad de Granada
instname
Mitohormesis is an adaptive response induced by a mild mitochondrial stress that promotes longevity and metabolic health in different organisms. This mechanism has been proposed as the cause of the increase in the survival in Coq7+/− (Mclk1+/−) m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fe2f9f68fb3a543fa13e9cf5c7c74ee
http://hdl.handle.net/10481/57884
http://hdl.handle.net/10481/57884
Autor:
Carolina Doerrier, Jose A. García, Luis C. López, Francisco Ortiz, Darío Acuña-Castroviejo, José C. Dayoub, Ana López, Carmen Venegas, Huayqui Volt, Marta Luna-Sánchez, Germaine Escames
Publikováno v:
Journal of Pineal Research. 58:34-49
Mucositis is a common and distressing side effect of chemotherapy or radiotherapy that has potentially severe consequences, and no treatment is available. The purpose of this study was to analyze the molecular pathways involved in the development of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f51e4319b0f4f3b3ccf80a6189a48d8
https://doi.org/10.1111/jpi.12191
https://doi.org/10.1111/jpi.12191
Publikováno v:
Molecular Syndromology. 5:163-169
Primary coenzyme Q10 (CoQ10) deficiency is a rare mitochondrial disorder associated with 5 major clinical phenotypes: (1) encephalomyopathy, (2) severe infantile multisystemic disease, (3) cerebellar ataxia, (4) isolated myopathy, and (5) steroid-res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9feb390c9b55db3f78c6dadcbf49ba4f
https://doi.org/10.1159/000360494
https://doi.org/10.1159/000360494
Autor:
Carmen Venegas, Marta Luna-Sánchez, Luis C. López, Huayqui Volt, Carolina Doerrier, Ana López, Darío Acuña-Castroviejo, Germaine Escames, Francisco Ortiz, Jose A. García
Publikováno v:
Journal of Pineal Research. 56:71-81
While it is accepted that the high production of nitric oxide (NO˙) by the inducible nitric oxide synthase (iNOS) impairs cardiac mitochondrial function during sepsis, the role of neuronal nitric oxide synthase (nNOS) may be protective. During sepsi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfd30070703a79851005d0cee96bf540
https://doi.org/10.1111/jpi.12099
https://doi.org/10.1111/jpi.12099