Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Marta Lovotti"'
Autor:
Tim Keuler, Karl Gatterdam, Anil Akbal, Marta Lovotti, Michael Marleaux, Matthias Geyer, Eicke Latz, Michael Gütschow
Publikováno v:
Frontiers in Chemistry, Vol 9 (2021)
Extracellular signals drive the nucleation of the NLRP3 inflammasome which leads to the release of cytokines and causes inflammatory events. Hence, the inflammasome has gained enormous momentum in biomedical basic research. The detailed mechanisms of
Externí odkaz:
https://doaj.org/article/060eff53c04e4d01a5529a0937ec15ac
Autor:
Tomasz Próchnicki, Matilde B. Vasconcelos, Kim S. Robinson, Matthew S. J. Mangan, Dennis De Graaf, Kateryna Shkarina, Marta Lovotti, Lena Standke, Romina Kaiser, Rainer Stahl, Fraser G. Duthie, Maximilian Rothe, Kateryna Antonova, Lea-Marie Jenster, Zhi Heng Lau, Sarah Rösing, Nora Mirza, Clarissa Gottschild, Dagmar Wachten, Claudia Günther, Thomas A. Kufer, Florian I. Schmidt, Franklin L. Zhong, Eicke Latz
Publikováno v:
Nature immunology 24(4), 595-603 (2023). doi:10.1038/s41590-023-01451-y
Upon detecting pathogens or cell stress, several NOD-like receptors (NLRs) form inflammasome complexes with the adapter ASC and caspase-1, inducing gasdermin D (GSDMD)-dependent cell death and maturation and release of IL-1β and IL-18. The triggers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::951cef744dde927be85ce561d1cb4398
Autor:
Anil Akbal, Alesja Dernst, Marta Lovotti, Matthew S. J. Mangan, Róisín M. McManus, Eicke Latz
Publikováno v:
Cellular & molecular immunology 19(11), 1201-1214 (2022). doi:10.1038/s41423-022-00922-w
Cellular and Molecular Immunology
Cellular and Molecular Immunology
NOD-, LRR-, and pyrin domain-containing 3 (NLRP3) is a cytosolic innate immune sensor of cellular stress signals, triggered by infection and sterile inflammation. Upon detection of an activating stimulus, NLRP3 transitions from an inactive homo-oligo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ce1c4f5416b34b342207670b67960e6
https://pub.dzne.de/record/165241
https://pub.dzne.de/record/165241
Autor:
Marta Lovotti, Tim Keuler, Michael Gütschow, Matthias Geyer, Anil Akbal, Karl Gatterdam, Michael Marleaux, Eicke Latz
Publikováno v:
Frontiers in Chemistry
Frontiers in Chemistry, Vol 9 (2021)
Frontiers in Chemistry, Vol 9 (2021)
Extracellular signals drive the nucleation of the NLRP3 inflammasome which leads to the release of cytokines and causes inflammatory events. Hence, the inflammasome has gained enormous momentum in biomedical basic research. The detailed mechanisms of
Autor:
Sabine Dickhöfer, Oliver Hantschel, Hubert Kalbacher, Anita Delor, Franziska Herster, Jasmin Kümmerle-Deschner, Bodo Grimbacher, Carsten L. Greve, Xiao Liu, Ana Marcu, Samuel Wagner, Hao Wu, Liudmila Andreeva, Ana Tapia-Abellán, Yamel Cardona Gloria, Alexander N.R. Weber, Marta Lovotti, Eicke Latz, Michael Scharl, Markus W. Löffler, Maria Mateo Tortola, Olaf-Oliver Wolz, Nadine A. Schilling, Peter Düwell, Matthew Mangan, Sangeetha Shankar, Tzu-Hsuan Chang, Zsofia Bittner, Stefan Stevanovic, Karlotta Bosch, Francesca Bork, Marianne R. Spalinger
Publikováno v:
Journal of experimental medicine 218(11), e20201656 (2021). doi:10.1084/jem.20201656
Activity of the NLRP3 inflammasome, a critical mediator of inflammation, is controlled by accessory proteins, posttranslational modifications, cellular localization, and oligomerization. How these factors relate is unclear. We show that a well-establ
Autor:
Jasmin Kümmerle-Deschner, Peter Düwell, Matthew Mangan, Ana Marcu, Olaf-Oliver Wolz, Ana Tapia-Abellán, Franziska Herster, Sangeetha Shankar, Hao Wu, Sabine Dickhöfer, Marta Lovotti, Anita Delor, Samuel Wagner, Liudmila Andreeva, Eicke Latz, Hubert Kalbacher, Markus W. Löffler, Bodo Grimbacher, Zsofia Bittner, Alexander N.R. Weber, Xiao Liu, Karlotta Bosch, Nadine A. Schilling, Stefan Stevanovic
Activity of the NLRP3 inflammasome, a critical mediator of inflammation (1), is controlled by accessory proteins (2, 3), post-translational modifications (4, 5), cellular localization (6, 7) and oligomerization (8). How these factors relate, is uncle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::750f84b4b4fe9a704faa78e0a1d51e60
https://doi.org/10.1101/864702
https://doi.org/10.1101/864702