Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Marta Leśniczak-Staszak"'
Publikováno v:
Biomolecules, Vol 14, Iss 10, p 1263 (2024)
Antibiotics targeting the bacterial ribosome are essential to combating bacterial infections. These antibiotics bind to various sites on the ribosome, inhibiting different stages of protein synthesis. This review provides a comprehensive overview of
Externí odkaz:
https://doaj.org/article/b0bdbff2b8804bd68e2bcbf071cba3b0
Autor:
Joanna Walczak-Sztulpa, Anna Wawrocka, Łukasz Kuszel, Paulina Pietras, Marta Leśniczak-Staszak, Mirosław Andrusiewicz, Maciej R. Krawczyński, Anna Latos-Bieleńska, Marta Pawlak, Ryszard Grenda, Anna Materna-Kiryluk, Machteld M. Oud, Witold Szaflarski
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
Background: Cranioectodermal dysplasia (CED) is a skeletal autosomal recessive ciliopathy. The characteristic clinical features of CED are facial dysmorphisms, short limbs, narrow thorax, brachydactyly, ectodermal abnormalities, and renal insufficien
Externí odkaz:
https://doaj.org/article/0e0d5cf622d04179ab39c703254bd1dc
Autor:
Paulina Pietras, Anaïs Aulas, Marta M. Fay, Marta Leśniczak-Staszak, Mateusz Sowiński, Shawn M. Lyons, Witold Szaflarski, Pavel Ivanov
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 145, Iss , Pp 112382- (2022)
Platinum-based antineoplastic drugs, such as cisplatin, are commonly used to induce tumor cell death. Cisplatin is believed to induce apoptosis as a result of cisplatin-DNA adducts that inhibit DNA and RNA synthesis. Although idea that DNA damage und
Externí odkaz:
https://doaj.org/article/e1950fe9973046578127c4bb440eb387
Autor:
Iwona Mazur-Michałek, Marcin Ruciński, Mateusz Sowiński, Paulina Pietras, Marta Leśniczak-Staszak, Witold Szaflarski, Mark Isalan, Michal Mielcarek
Publikováno v:
Cells, Vol 11, Iss 10, p 1675 (2022)
Ocular abnormalities are becoming associated with a spectrum of pathological events in various neurodegenerative diseases. Huntington’s disease (HD) is just such an example of a fatal neurological disorder, where mutated genes (CAG trinucleotide ex
Externí odkaz:
https://doaj.org/article/40b13b4accdf495d9ef0f26d97b5e93b
Autor:
Iwona Mazur-Michałek, Katarzyna Kowalska, Daniel Zielonka, Marta Leśniczak-Staszak, Paulina Pietras, Witold Szaflarski, Mark Isalan, Michal Mielcarek
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 10; Pages: 5450
Huntington’s disease (HD) is a fatal neurodegenerative disorder caused by a polyglutamine expansion in the huntingtin protein. HD-related pathological remodelling has been reported in HD mouse models and HD carriers. In this study, we studied struc
Autor:
Witold Szaflarski, Marta Leśniczak-Staszak, Mateusz Sowiński, Sandeep Ojha, Anaïs Aulas, Dhwani Dave, Sulochan Malla, Paul Anderson, Pavel Ivanov, Shawn M Lyons
Publikováno v:
Nucleic Acids Research
Nucleic Acids Research, 2022, 50 (2), pp.1033-1051. ⟨10.1093/nar/gkab1231⟩
Nucleic Acids Research, 2022, 50 (2), pp.1033-1051. ⟨10.1093/nar/gkab1231⟩
The production of ribosomes is an energy-intensive process owing to the intricacy of these massive macromolecular machines. Each human ribosome contains 80 ribosomal proteins and four non-coding RNAs. Accurate assembly requires precise regulation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57dca1df62e40db37c01ea5d0e633999
https://hal-amu.archives-ouvertes.fr/hal-04085337
https://hal-amu.archives-ouvertes.fr/hal-04085337
Autor:
Pavel Ivanov, Aldona Kasprzak, Mateusz Sowiński, Małgorzata Andrzejewska, Marta Leśniczak-Staszak, Paulina Pietras, Marcin Rucinski, Witold Szaflarski, Karol Jopek, Shawn M. Lyons
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 12121, p 12121 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 22
International Journal of Molecular Sciences
Volume 22
Issue 22
Cancer cells show significant dysregulation of genes expression, which may favor their survival in the tumor environment. In this study, the cellular vault’s components MVP (major vault protein), TEP1 (telomerase-associated protein 1) and vPARP (va