Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Marta Larráyoz"'
Autor:
Ivana Grbesa, María J Pajares, Elena Martínez-Terroba, Jackeline Agorreta, Ana-Matea Mikecin, Marta Larráyoz, Miguel A Idoate, Koraljka Gall-Troselj, Ruben Pio, Luis M Montuenga
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0124670 (2015)
BACKGROUND:Sirtuin 1 (SIRT1) and sirtuin 2 (SIRT2) are NAD+-dependent protein deacetylases involved in the regulation of key cancer-associated genes. In this study we evaluated the relevance of these deacetylases in lung cancer biology. MATERIAL AND
Externí odkaz:
https://doaj.org/article/4a5e947f31154ebf86d37dc3155d1bc8
Autor:
Cirino Botta, Cristina Perez, Marta Larrayoz, Noemi Puig, Maria-Teresa Cedena, Rosalinda Termini, Ibai Goicoechea, Sara Rodriguez, Aintzane Zabaleta, Aitziber Lopez, Sarai Sarvide, Laura Blanco, Daniele M. Papetti, Marco S. Nobile, Daniela Besozzi, Massimo Gentile, Pierpaolo Correale, Sergio Siragusa, Albert Oriol, Maria Esther González-Garcia, Anna Sureda, Felipe de Arriba, Rafael Rios Tamayo, Jose-Maria Moraleda, Mercedes Gironella, Miguel T. Hernandez, Joan Bargay, Luis Palomera, Albert Pérez-Montaña, Hartmut Goldschmidt, Hervé Avet-Loiseau, Aldo Roccaro, Alberto Orfao, Joaquin Martinez-Lopez, Laura Rosiñol, Juan-José Lahuerta, Joan Blade, Maria-Victoria Mateos, Jesús F. San-Miguel, Jose-Angel Martinez Climent, Bruno Paiva, the Programa Para el Estudio de la Terapéutica en Hemopatías Malignas/Grupo Español de Mieloma (PETHEMA/GEM) cooperative group, the iMMunocell study group
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Tumor recognition by T cells is essential for antitumor immunity. A comprehensive characterization of T cell diversity may be key to understanding the success of immunomodulatory drugs and failure of PD-1 blockade in tumors such as multiple
Externí odkaz:
https://doaj.org/article/2de8f8a904e64dd0bd9521c3f7eaa173
Autor:
Karmele Valencia, Cristina Sainz, Cristina Bértolo, Gabriel de Biurrun, Jackeline Agorreta, Arantza Azpilikueta, Marta Larrayoz, Graziella Bosco, Carolina Zandueta, Miriam Redrado, Esther Redín, Francisco Exposito, Diego Serrano, Mirari Echepare, Daniel Ajona, Ignacio Melero, Ruben Pio, Roman Thomas, Alfonso Calvo, Luis M. Montuenga
Publikováno v:
Disease Models & Mechanisms, Vol 15, Iss 1 (2022)
There is a paucity of adequate mouse models and cell lines available to study lung squamous cell carcinoma (LUSC). We have generated and characterized two models of phenotypically different transplantable LUSC cell lines, i.e. UN-SCC679 and UN-SCC680
Externí odkaz:
https://doaj.org/article/c6029081bc0342b6bd4394720dcdfdaf
Autor:
Tomasz K. Wojdacz, Harindra E. Amarasinghe, Latha Kadalayil, Alice Beattie, Jade Forster, Stuart J. Blakemore, Helen Parker, Dean Bryant, Marta Larrayoz, Ruth Clifford, Pauline Robbe, Zadie A. Davis, Monica Else, Dena R. Howard, Basile Stamatopoulos, Andrew J. Steele, Richard Rosenquist, Andrew Collins, Andrew R. Pettitt, Peter Hillmen, Christoph Plass, Anna Schuh, Daniel Catovsky, David G. Oscier, Matthew J.J. Rose-Zerilli, Christopher C. Oakes, Jonathan C. Strefford
Publikováno v:
Blood Advances, Vol 3, Iss 16, Pp 2474-2481 (2019)
Abstract: Chronic lymphocytic leukemia patients with mutated immunoglobulin heavy-chain genes (IGHV-M), particularly those lacking poor-risk genomic lesions, often respond well to chemoimmunotherapy (CIT). DNA methylation profiling can subdivide earl
Externí odkaz:
https://doaj.org/article/cd01b8a978aa4041a72a417cc4cb4fcc
Autor:
Panagiotis Baliakas, Theodoros Moysiadis, Anastasia Hadzidimitriou, Aliki Xochelli, Sabine Jeromin, Andreas Agathangelidis, Mattias Mattsson, Lesley-Ann Sutton, Eva Minga, Lydia Scarfò, Davide Rossi, Zadie Davis, Neus Villamor, Helen Parker, Jana Kotaskova, Evangelia Stalika, Karla Plevova, Larry Mansouri, Diego Cortese, Alba Navarro, Julio Delgado, Marta Larrayoz, Emma Young, Achilles Anagnostopoulos, Karin E. Smedby, Gunnar Juliusson, Oonagh Sheehy, Mark Catherwood, Jonathan C. Strefford, Niki Stavroyianni, Chrysoula Belessi, Sarka Pospisilova, David Oscier, Gianluca Gaidano, Elias Campo, Claudia Haferlach, Paolo Ghia, Richard Rosenquist, Kostas Stamatopoulos
Publikováno v:
Haematologica, Vol 104, Iss 2 (2019)
Chronic lymphocytic leukemia (CLL) patients with differential somatic hypermutation status of the immunoglobulin heavy variable genes, namely mutated or unmutated, display fundamental clinico-biological differences. Considering this, we assessed prog
Externí odkaz:
https://doaj.org/article/52a899077fd1453f94e9b19946a4d882
Autor:
Marta Larrayoz, Ruben Pio, María J Pajares, Isabel Zudaire, Daniel Ajona, Oriol Casanovas, Luis M Montuenga, Jackeline Agorreta
Publikováno v:
EMBO Molecular Medicine, Vol 6, Iss 4, Pp 539-550 (2014)
Abstract The vascular endothelial growth factor (VEGF) pathway is a clinically validated antiangiogenic target for non‐small cell lung cancer (NSCLC). However, some contradictory results have been reported on the biological effects of antiangiogeni
Externí odkaz:
https://doaj.org/article/b56b9f6b31ae4699a0952ff340464a73
Autor:
Lesley-Ann Sutton, Emma Young, Panagiotis Baliakas, Anastasia Hadzidimitriou, Theodoros Moysiadis, Karla Plevova, Davide Rossi, Jana Kminkova, Evangelia Stalika, Lone Bredo Pedersen, Jitka Malcikova, Andreas Agathangelidis, Zadie Davis, Larry Mansouri, Lydia Scarfò, Myriam Boudjoghra, Alba Navarro, Alice F. Muggen, Xiao-Jie Yan, Florence Nguyen-Khac, Marta Larrayoz, Panagiotis Panagiotidis, Nicholas Chiorazzi, Carsten Utoft Niemann, Chrysoula Belessi, Elias Campo, Jonathan C. Strefford, Anton W. Langerak, David Oscier, Gianluca Gaidano, Sarka Pospisilova, Frederic Davi, Paolo Ghia, Kostas Stamatopoulos, Richard Rosenquist
Publikováno v:
Haematologica, Vol 101, Iss 8 (2016)
We report on markedly different frequencies of genetic lesions within subsets of chronic lymphocytic leukemia patients carrying mutated or unmutated stereotyped B-cell receptor immunoglobulins in the largest cohort (n=565) studied for this purpose. B
Externí odkaz:
https://doaj.org/article/565f9a6095ed413e91b042f8d0c0b812