Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Marta H Kubala"'
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0120716 (2015)
Protein prenylation is a widespread and highly conserved eukaryotic post-translational modification that endows proteins with the ability to reversibly attach to intracellular membranes. The dynamic interaction of prenylated proteins with intracellul
Externí odkaz:
https://doaj.org/article/ef9dacf66f1940b79ae3e9095988755d
Autor:
Helen L Barrett, Marta H Kubala, Katherin Scholz Romero, Kerina J Denny, Trent M Woodruff, H David McIntyre, Leonie K Callaway, Marloes Dekker Nitert
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e104826 (2014)
Infants of women with gestational diabetes mellitus (GDM) are more likely to be born large for gestational age with a higher percentage body fat. Elevated maternal lipids may contribute to this. Placental lipases such as lipoprotein lipase (LPL), end
Externí odkaz:
https://doaj.org/article/e53ffa888ef4407faab5d987ab59d923
Autor:
Wayne A. Johnston, Marta H. Kubala, Sergey Mureev, Guillermo A. Gomez, Kirill Alexandrov, Alpha S. Yap, Alun Jones, Suzanne J. Norwood
Publikováno v:
Biochemical and Biophysical Research Communications. 468:580-586
The protein farnesyltransferase (FTase) mediates posttranslational modification of proteins with isoprenoid lipids. FTase is a heterodimer and although the beta subunit harbors the active site, it requires the a subunit for its activity. Here we expl
Autor:
Marta H. Kubala, Yves A. DeClerck
Publikováno v:
Journal of visualized experiments : JoVE. (129)
siRNA and shRNA-mediated knock down (KD) methods of regulating gene expression are invaluable tools for understanding gene and protein function. However, in the case that the KD of the protein of interest has a lethal effect on cells or the anticipat
Autor:
Kai Chen, Marta H. Kubala, Anita C. Jones, Gintautas Tamulaitis, Robert K. Neely, Virginijus Siksnys
Publikováno v:
Nucleic Acids Research
Neely, R K, Tamulaitis, G, Chen, K, Kubala, M, Siksnys, V & Jones, A C 2009, ' Time-resolved fluorescence studies of nucleotide flipping by restriction enzymes ', Nucleic Acids Research, vol. 37, no. 20, pp. 6859-6870 . https://doi.org/10.1093/nar/gkp688
Neely, R K, Tamulaitis, G, Chen, K, Kubala, M, Siksnys, V & Jones, A C 2009, ' Time-resolved fluorescence studies of nucleotide flipping by restriction enzymes ', Nucleic Acids Research, vol. 37, no. 20, pp. 6859-6870 . https://doi.org/10.1093/nar/gkp688
Restriction enzymes Ecl18kI, PspGI and EcoRII-C, specific for interrupted 5-bp target sequences, flip the central base pair of these sequences into their protein pockets to facilitate sequence recognition and adjust the DNA cleavage pattern. We have
Autor:
Marta H. Kubala, Katherin Scholz-Romero, H. David McIntyre, Helen L. Barrett, Leonie K. Callaway, Marloes Dekker Nitert
Publikováno v:
Reproductive Biology and Endocrinology : RB&E
Background Preeclampsia (PE) is associated with alterations of placental function. The incidence of PE is higher in insulin resistant states. Women with PE have high circulating levels of the metabolic regulator fibroblast growth factor 21 (FGF21). F
Publikováno v:
Cancer Research. 77:3061-3061
Macrophages can exhibit a spectrum of activation states ranging from a pro-inflammatory and antitumorigenic M1 (CD80+; IL-12high; iNOShigh) to a pro-tumorigenic M2 [CD163+; IL-10high; CD206+; Arg+ (mouse)] phenotype. Plasminogen activator inhibitor-1
Autor:
Marloes Dekker Nitert, H. David McIntyre, Helen L. Barrett, Kerina J. Denny, Marta H. Kubala, Trent M. Woodruff, Katherin Scholz Romero, Leonie K. Callaway
Publikováno v:
The Journal of clinical endocrinology and metabolism. 99(4)
Fibroblast growth factor 21 (FGF21) can regulate glucose and lipid metabolism. The placenta actively synthesizes and secretes many hormones, but it is unknown whether this includes FGF21. This study aimed to analyze the placental expression of FGF21
Autor:
Kirill Alexandrov, Oleksiy Kovtun, Wayne A. Johnston, WooRam Jung, Marta H. Kubala, Sergey Mureev
Publikováno v:
Methods (San Diego, Calif.). 55(1)
Cell-free protein expression is an important tool for a rapid production, engineering and labeling of recombinant proteins. However the complex protocols for preparation of eukaryotic cell-free protein expression systems result in high manufacturing
The green fluorescent protein (GFP)-nanobody is a single-chain VHH antibody domain developed with specific binding activity against GFP and is emerging as a powerful tool for isolation and cellular engineering of fluorescent protein fusions in many d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0485005f413fa9ef13579a7febd93b19
https://europepmc.org/articles/PMC3009406/
https://europepmc.org/articles/PMC3009406/