Visible-Light Optical Coherence Tomography Fibergraphy of the Tree Shrew Retinal Ganglion Cell Axon Bundles

Autor: David A. Miller, Marta Grannonico, Mingna Liu, Elise Savier, Kara McHaney, Alev Erisir, Peter A. Netland, Jianhua Cang, Xiaorong Liu, Hao F. Zhang

Publikováno v: bioRxiv

We seek to develop techniques for high-resolution imaging of the tree shrew retina for visualizing and parameterizing retinal ganglion cell (RGC) axon bundles in vivo. We applied visible-light optical coherence tomography fibergraphy (vis-OCTF) and t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18d359e21fedb50110304d0e58161ed0
https://doi.org/10.1101/2023.05.16.541062

Long-term retinal protection by MEK inhibition in Pax6 haploinsufficiency mice

Autor: James D. Cole, Kara M. McHaney, Behnam Rabiee, Jingyi Gao, Carlos Rodriguez, David A. Miller, Mingna Liu, Marta Grannonico, Pedro Norat, Hao F. Zhang, Ali R. Djalilian, Xiaorong Liu

Publikováno v: Exp Eye Res

Aniridia is a panocular condition characterized by impaired eye development and vision, which is mainly due to the haploinsufficiency of the paired-box-6 (PAX6) gene. Like what is seen in aniridia patients, Pax6-deficient mice Pax6(Sey-Neu/+) exhibit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab0f1fa5e082f8c0a9742e1131188f26
https://europepmc.org/articles/PMC9050935/

In vivo imaging of the inner retinal layer structure in mice after eye-opening using visible-light optical coherence tomography

Autor: Mingna Liu, Lisa Beckmann, Hyun Jung Ryu, James Cole, Zhen Cai, Marta Grannonico, Xiaorong Liu, Xian Zhang, Peter A. Netland, Hao Zhang, David Miller

Publikováno v: Exp Eye Res

The growth of the mouse eye and retina after birth is a dynamic, highly regulated process. In this study, we applied visible-light optical coherence tomography (vis-OCT), a non-invasive imaging technique, to examine developing retinal layer structure

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09b16206717a6677b402f2e01e921c6d
https://pubmed.ncbi.nlm.nih.gov/34492282

Visible-Light Optical Coherence Tomography Fibergraphy for Quantitative Imaging of Retinal Ganglion Cell Axon Bundles

Autor: Marta Grannonico, Roman V. Kuranov, Xiaorong Liu, David Miller, Peter A. Netland, Mingna Liu, Hao Zhang

Publikováno v: Translational Vision Science & Technology

Purpose To develop a practical technique for visualizing and quantifying retinal ganglion cell (RGC) axon bundles in vivo. Methods We applied visible-light optical coherence tomography (vis-OCT) to image the RGC axon bundles, referred to as vis-OCT f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d30c4936e74a8a884022c9d358e5af81
http://europepmc.org/articles/PMC7552935

DF3016A induces increased BDNF transcription in ischemic neuroinflammation injury

Autor: Antonella Paladini, Pierluigi Sebastiani, Giustino Varrassi, Alba Piroli, Alessia Colanardi, Laura Brandolini, Marta Grannonico, Marcello Allegretti, Silvia Di Loreto

Publikováno v: Brain research 1748 (2020): 1–12. doi:10.1016/j.brainres.2020.147057
info:cnr-pdr/source/autori:Grannonico M.; Brandolini L.; Varrassi G.; Sebastiani P.; Colanardi A.; Paladini A.; Piroli A.; Allegretti M.; Di Loreto S./titolo:DF3016A induces increased BDNF transcription in ischemic neuroinflammation injury/doi:10.1016%2Fj.brainres.2020.147057/rivista:Brain research/anno:2020/pagina_da:1/pagina_a:12/intervallo_pagine:1–12/volume:1748

C5a is a crucial terminal effector of the C cascade, mostly involved in pain and neuroinflammatory conditions. DF3016A is a novel potent and selective C5a receptor (C5aR) inhibitor that crosses the blood-brain barrier (BBB) and may have pharmacologic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10f6a4570ccb5ae142bbbd76571dc044
http://hdl.handle.net/11697/149378