Výsledky vyhledávání - "Marta Grandal"

Akademický článek

Impact of Previous Common Human Coronavirus Exposure on SARS-CoV-2-Specific T-Cell and Memory B-Cell Response after mRNA-Based Vaccination

Autor: José L. Casado, Pilar Vizcarra, Adrián Martín-Hondarza, Magdalena Blasco, Marta Grandal-Platero, Johannes Haemmerle, Marina Fernández-Escribano, Alejandro Vallejo

Publikováno v: Viruses, Vol 15, Iss 3, p 627 (2023)

Objective: T-cell responses against SARS-CoV-2 are observed in unexposed individuals, attributed to previous common human coronavirus (HCoV) infections. We evaluated the evolution of this T-cell cross-reactive response and the specific memory B-cells

Externí odkaz: https://doaj.org/article/4644699cfa8f40dfbd776166b8c05074

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Autor: Marta Grandal, Andrés Tabernilla, Álvaro Mena, Iria Rodríguez-Osorio, Ángeles Castro-Iglesias, Manuel Delgado, Eva Poveda, Berta Pernas, Purificación Cid, José Pedreira

Publikováno v: European Journal of Gastroenterology & Hepatology. 29:781-785

ObjectivesDirect-acting antiviral agents (DAAs) have provided an ultimate treatment duration of 12 weeks for most hepatitis C virus (HCV)-infected patients. The opportunity to reduce treatment duration to 6 or 8 weeks is being evaluated. Here, the HC

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b37da66edc1b96819fdf25398bebf8c7
https://doi.org/10.1097/meg.0000000000000882

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Prevalence of NS5A resistance associated substitutions in patients with hepatitis C virus genotypes 1a and 3: Impact on current therapeutic strategies

Autor: Marta Grandal, Álvaro Mena, Manuel Delgado, Berta Pernas, Ana Mariño, Hortensia Álvarez, Nieves Valcarce, Ana B. Pérez, Eva Poveda, Andrés Tabernilla, Ángeles Castro-Iglesias

Publikováno v: RUC. Repositorio da Universidade da Coruña
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[Abstract] The presence of resistance‐associated substitutions (RASs) at NS5A region might compromise the efficacy of Direct Acting Antiviral agents (DAAs). HCV resistance at NS5A region is mainly focused on patients with hepatitis C virus (HCV) ge

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2aad7b092ae15cd93d4287eb797adb38
https://hdl.handle.net/2183/20798

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Trends on epidemiological, virological, and clinical features among newly diagnosed HIV-1 persons in Northwest Spain over the last 10 years

Autor: Sonia Pértega, José Pedreira, Ángeles Castro-Iglesias, Marta Grandal, Angelina Cañizares, Álvaro Mena, Eva Poveda, Berta Pernas

Publikováno v: Journal of Medical Virology. 87:1319-1326

To describe temporal trend and characteristics of newly HIV-diagnosed patients in a medical care area in Northwest Spain over the last 10 years. All newly diagnosed patients for HIV-infection from 2004 to 2013 at a reference medical care area in Nort

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0883a7c6c0803ac18b518678f46d73d1
https://doi.org/10.1002/jmv.24185

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Molecular characterization of HIV-1 infection in Northwest Spain (2009–2013): Investigation of the subtype F outbreak

Autor: Berta Pernas, Javier Maseda Rodríguez, Marta Grandal, Ángeles Castro-Iglesias, Evangelia Georgia Kostaki, Eva Poveda, Antonio Aguilera, Dimitrios Paraskevis, Angelina Cañizares, Álvaro Mena, Apostolos Beloukas, José Pedreira

Publikováno v: RUC. Repositorio da Universidade da Coruña
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[Abstract] Background. HIV-1 subtype B is the predominant one in European regions several, while other subtypes and recombinants are also circulating with high prevalence. A sub-epidemic of subtype F with specific characteristics and low response to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::253ddce1c788ee011a1d4d6cd16982d6
https://doi.org/10.1016/j.meegid.2014.12.012

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Plasma mitochondrial DNA levels are inversely associated with HIV-RNA levels and directly with CD4 counts: potential role as a biomarker of HIV replication

Autor: Álvaro Mena, Manuel Crespo, Ignacio Rego-Pérez, Francisco J. Blanco, S. Relaño, Vanesa Balboa, Andrés Tabernilla, Marta Grandal, Berta Pernas, Eva Poveda, Ángeles Castro-Iglesias

Publikováno v: RUC. Repositorio da Universidade da Coruña
instname

[Abstract] Objectives. To evaluate plasma mitochondrial DNA (mtDNA) levels among HIV-infected patients and its potential role as a biomarker of residual viral replication. Methods. HIV-infected patients on follow-up at a reference hospital in north-w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::733ffc6e74d3cf68091af12561062b1f
https://hdl.handle.net/2183/20799

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Short article: Viral dynamics among hepatitis C virus chronic infected patients during direct-acting antiviral agents therapy: impact for monitoring and optimizing treatment duration

Autor: Andres, Tabernilla, Marta, Grandal, Berta, Pernas, Angeles, Castro-Iglesias, Iria, Rodríguez-Osorio, Alvaro, Mena, Manuel, Delgado, Purificacion, Cid, Jose D, Pedreira, Eva, Poveda

Publikováno v: European journal of gastroenterologyhepatology. 29(7)

Direct-acting antiviral agents (DAAs) have provided an ultimate treatment duration of 12 weeks for most hepatitis C virus (HCV)-infected patients. The opportunity to reduce treatment duration to 6 or 8 weeks is being evaluated. Here, the HCV viral dy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e69587c7dd91825f76da8e1cfe57417a
https://pubmed.ncbi.nlm.nih.gov/28410351

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High prevalence of subtype F in newly diagnosed HIV-1 persons in northwest Spain and evidence for impaired treatment response

Autor: Marta Grandal, José Pedreira, Sonia Pértega, Soledad López-Calvo, Eva Poveda, Ángeles Castro-Iglesias, David L. Wyles, Iria Rodríguez-Osorio, Berta Pernas, Angelina Cañizares, Álvaro Mena

Publikováno v: AIDS. 28:1837-1840

HIV-1 non-B subtype variants were found in 37.8% of 296 newly diagnosed persons in northwest Spain over the past 5 years. Subtype F was the most prevalent non-B subtype (29.6%) and displayed preferential transmission among MSM. Virologic response rat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2199f68ca07a8590bb943b8761a0a40
https://doi.org/10.1097/qad.0000000000000326

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Characterization of chronic HCV infection in Northwest Spain: Impact of the treatment strategic plan of the Spanish National Health Service on HCV cure

Autor: Manuel Delgado, Berta Pernas, Ana Mariño, Sonia Pértega, Álvaro Mena, Ángeles Castro-Iglesias, Andrés Tabernilla, Eva Poveda, Marta Grandal, Hortensia Álvarez

Publikováno v: RUC. Repositorio da Universidade da Coruña
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[Abstract] The aim of the study was to characterize HCV infection in Northwest Spain and assess the impact of the Spanish Strategic Plan to cure HCV infection. Overall, 387 patients were included (60.9% HIV/HCV coinfected and 28.2% cirrhotic). Of the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c819dfe6df246f01882d2de73efd37de
https://pubmed.ncbi.nlm.nih.gov/28079256

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