Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Marta Gerasymchuk"'
Autor:
Marta Gerasymchuk, Gregory Ian Robinson, Nataliia Vardinska, Samuel Abiola Ayedun, Sandra Chinwe Alozie, John Wesley Robinson, Olga Kovalchuk, Igor Kovalchuk
Publikováno v:
Dermato, Vol 3, Iss 3, Pp 196-223 (2023)
The skin, the largest external organ, serves as the primary defensive barrier against various environmental factors such as ultraviolet exposure, pollution, dietary habits, pathogens, and chemical compounds. Consequently, the skin reflects our age th
Externí odkaz:
https://doaj.org/article/22b045c9a5314f26937ed906ce07e76a
Autor:
Gregory Ian Robinson, Dongping Li, Bo Wang, Yeva Zahoruiko, Marta Gerasymchuk, Darryl Hudson, Olga Kovalchuk, Igor Kovalchuk
Publikováno v:
Current Issues in Molecular Biology, Vol 45, Iss 8, Pp 6743-6774 (2023)
Intestinal inflammation and dysbiosis can lead to inflammatory bowel diseases (IBD) and systemic inflammation, affecting multiple organs. Developing novel anti-inflammatory therapeutics is crucial for preventing IBD progression. Serotonin receptor ty
Externí odkaz:
https://doaj.org/article/0c1e90f9df7b4edcb57099be32c8d21c
Autor:
Gregory Ian Robinson, Dongping Li, Bo Wang, Tahiat Rahman, Marta Gerasymchuk, Darryl Hudson, Olga Kovalchuk, Igor Kovalchuk
Publikováno v:
Life, Vol 13, Iss 12, p 2345 (2023)
Inflammation plays a pivotal role in the development and progression of inflammatory bowel disease (IBD), by contributing to tissue damage and exacerbating the immune response. The investigation of serotonin receptor 2A (5-HT2A) ligands and transient
Externí odkaz:
https://doaj.org/article/94c0165d75914432803d96205c8b4f48
Autor:
Timur Zanikov, Marta Gerasymchuk, Esmaeel Ghasemi Gojani, Gregory Ian Robinson, Shima Asghari, Alyssa Groves, Lucie Haselhorst, Sanjana Nandakumar, Cora Stahl, Mackenzie Cameron, Dongping Li, Rocio Rodriguez-Juarez, Alexandra Snelling, Darryl Hudson, Anna Fiselier, Olga Kovalchuk, Igor Kovalchuk
Publikováno v:
Molecules, Vol 28, Iss 6, p 2624 (2023)
Inflammation is an organism’s biological defense mechanism. Acute and chronic inflammation of the body triggers the production of pro- and anti-inflammatory pathways that can affect the content of cytokines in the brain and thus cause brain inflamm
Externí odkaz:
https://doaj.org/article/d9e02854bd0246e2a098c197e3cd57b6
Phytocannabinoids Stimulate Rejuvenation and Prevent Cellular Senescence in Human Dermal Fibroblasts
Autor:
Marta Gerasymchuk, Gregory Ian Robinson, Alyssa Groves, Lucie Haselhorst, Sanjana Nandakumar, Cora Stahl, Olga Kovalchuk, Igor Kovalchuk
Publikováno v:
Cells, Vol 11, Iss 23, p 3939 (2022)
In light of the increased popularity of phytocannabinoids (pCBs) and their appearance in beauty products without rigorous research on their rejuvenation efficacy, we decided to investigate the potential role of pCBs in skin rejuvenation. Utilizing he
Externí odkaz:
https://doaj.org/article/7468586558eb4ca7a82584bb12852311
Autor:
Viktoriia Cherkasova, Bo Wang, Marta Gerasymchuk, Anna Fiselier, Olga Kovalchuk, Igor Kovalchuk
Publikováno v:
Cancers, Vol 14, Iss 20, p 5142 (2022)
The endocannabinoid system (ECS) is an ancient homeostasis mechanism operating from embryonic stages to adulthood. It controls the growth and development of many cells and cell lineages. Dysregulation of the components of the ECS may result in uncont
Externí odkaz:
https://doaj.org/article/b47ef3a4a7d34ebc9b6191e96bc074da
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 15, p 8804 (2022)
Identifying effective anti-aging compounds is a cornerstone of modern longevity, aging, and skin-health research. There is considerable evidence of the effectiveness of nutrient signaling regulators such as metformin, resveratrol, and rapamycin in lo
Externí odkaz:
https://doaj.org/article/6ff72feb97ff4e8e96d6408117b82c7c
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 13, p 7124 (2022)
Modern understanding of aging is based on the accumulation of cellular damage during one’s life span due to the gradual deterioration of regenerative mechanisms in response to the continuous effect of stress, lifestyle, and environmental factors, f
Externí odkaz:
https://doaj.org/article/d445aac3048b4f1c9cc952eb7eaa783a
Autor:
Bo Wang, Dongping Li, Viktoriia Cherkasova, Marta Gerasymchuk, Aru Narendran, Igor Kovalchuk, Olga Kovalchuk
Publikováno v:
Cancers, Vol 14, Iss 8, p 1908 (2022)
High-risk neuroblastoma is an aggressive pediatric tumor. Despite great advances in neuroblastoma therapy and supportive care protocols, no curative treatment is available for most patients with this disease. Here, we uncover that CBN attenuated the
Externí odkaz:
https://doaj.org/article/8214ca8a6be54a21b74abdf05974189f
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 15, p 5281 (2020)
The aging process starts directly after birth and lasts for the entire lifespan; it manifests itself with a decline in an organism’s ability to adapt and is linked to the development of age-related diseases that eventually lead to premature death.
Externí odkaz:
https://doaj.org/article/8b6ece3bf38e4c9a826490820890015e