Výsledky vyhledávání - "Marta Garijo Añorbe"

Varying Acidity of Aqua Ligands in Dependence on the Microenvironment in Mononucleobase (nb) Complexes of Type cis- and trans-[Pt(NH3)2(nb)(H2O)]n+

Autor: Barbara Müller, Marta Garijo Añorbe, Patrick Lax, Egla Yareth Bivián-Castro, Bernhard Lippert

Publikováno v: Inorganic Chemistry. 46:4036-4043

Aqua ligands in mixed aqua/nucleobase metal complexes are potential sites of acid-base catalysis and/or, when present as hydroxo ligands, can directly be involved in hydrolysis reactions. pKa values of close to 7 are consequently of particular intere

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f15fd43218c4fefacf57d661b85b4e5a
https://doi.org/10.1021/ic062379h

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On-line coupling of gel electrophoresis (GE) and inductively coupled plasma-mass spectrometry (ICP-MS) for the detection of Fe in metalloproteins

Autor: Jiirgen Messerschmidt, Ingo Feldmann, Norbert Jakubowski, Marta Garijo Añorbe

Publikováno v: J. Anal. At. Spectrom.. 22:917-924

In this paper, we have coupled on-line gel electrophoresis to ICP-MS to investigate the separation of iron containing proteins (cytochrome C, haemoglobin, transferrin and ferritin). The GE system has been operated with quite different conditions, usi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7a69fcdea0162fdf8daad5a6ca0f6d92
https://doi.org/10.1039/b704541g

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Connectivity patterns and rotamer states of nucleobases determine acid-base properties of metalated purine quartets

Autor: Bert P. Operschall, Bernhard Lippert, Marc Sven Lüth, Marta Garijo Añorbe, Gunnar Kampf, Rolf Griesser, Eva Freisinger, Helmut Sigel

Publikováno v: Journal of inorganic biochemistry. 148

Potentiometric pH titrations and pD dependent (1)H NMR spectroscopy have been applied to study the acidification of the exocyclic amino group of adenine (A) model nucleobases (N9 position blocked by alkyl groups) when carrying trans-a2Pt(II) (with a=

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e40e2eaadd0aae1c1f01ad8ed82c6a2e
https://pubmed.ncbi.nlm.nih.gov/25773716

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Multiple metal binding to the 9-methyladenine model nucleobase involving N1, N6, and N7: discrete di- and trinuclear species with different combinations of monofunctional Pd(II) and Pt(II) entities

Autor: Pablo J. Sanz Miguel, Marta Garijo Añorbe, Tímea Mihály, Bernhard Lippert, Francisca M. Albertí

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
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Several di- and trinuclear metal complexes consisting of the model nucleobase 9-methyladenine (9-MeA) or its mono-deprotonated form (9-MeA -) and monofunctional (dien)Pd II, (dien)Pt II, (NH 3) 3Pt II, or (trpy)Pd II in different combinations have be

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b568be437c7f5fc20dbdc1ad1c4d130
https://pubmed.ncbi.nlm.nih.gov/22967318

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Migration of a cis-(NH3)2PtII moiety along two adenine nucleobases, from N1 to N6, is markedly facilitated by additional PtII entities coordinated to N7

Autor: Bernhard Lippert, Marta Garijo Añorbe, Thea Welzel

Publikováno v: Inorganic chemistry. 46(20)

Adenine acidification as a consequence of simultaneous Pt" binding to N1 and N7 facilitates deprotonation of the exocyclic N(6)H 2 group and permits Pt" migration from N1 to N6 under mild conditions. Starting from the trinuclear complex cis-[(NH3)2Pt

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e91fa87b01f4dfa42f1620f7152b76d8
https://pubmed.ncbi.nlm.nih.gov/17824698

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The role of intramolecular hydrogen bonding on nucleobase acidification following metal coordination: possible implications of an 'indirect' role of metals in acid-base catalysis of nucleic acids

Autor: Bernhard Lippert, Pablo J. Sanz Miguel, Barbara Müller, Marta Garijo Añorbe, Michael Roitzsch

Publikováno v: Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry. 10(7)

The acidifying effect of Pt(II) on nucleobase -NH and -NH2 groups depends both on the site of metal coordination and on the efficiency of stabilization of the deprotonated nucleobase via intracomplex hydrogen bonding. Weakly acidic nucleobase protons

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4df835cb76d9739c0655a53ef66aa400
https://pubmed.ncbi.nlm.nih.gov/16231130

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Perturbation of the NH2 pKa value of adenine in platinum(II) complexes: distinct stereochemical internucleobase effects

Autor: Bernhard Lippert, Patrick Lax, Marc Sven Lüth, Michael Roitzsch, Gunnar Kampf, Marta Garijo Añorbe, Marta Morell Cerdà, Helmut Sigel

Publikováno v: Scopus-Elsevier

The degree of acidification of the exocyclic N6 amino group of the model nucleobase 9-methyladenine (9MeA) in relation to the number and site(s) of Pt I I binding has been studied in detail. It is found that twofold Pt I I binding to N1 and N7 lowers

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8e4d19d9a504cb2b3332fe09ba35862
https://pubmed.ncbi.nlm.nih.gov/14978832

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Labelling of proteins by use of iodination and detection by ICP-MS

Autor: Larissa Waentig, Juergen Messerschmidt, Peter H. Roos, Heiko Hayen, Marta Garijo Añorbe, Norbert Jakubowski

Publikováno v: Journal of Analytical Atomic Spectrometry. 23:1487

The labelling of three different proteins, bovine serum albumin (BSA), chicken egg white lysozyme and porcine gastric mucosa pepsin, with iodine using a commercially available reaction kit has been investigated for total protein amounts of 500 μg. T

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::080045b4fc0cab71a915110e85a2b7a8
https://doi.org/10.1039/b718074h

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