Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Marta García-Canãdas"'
Autor:
Sabine Klawitter, Nina V. Fuchs, Kyle R. Upton, Martin Muñoz-Lopez, Ruchi Shukla, Jichang Wang, Marta Garcia-Cañadas, Cesar Lopez-Ruiz, Daniel J. Gerhardt, Attila Sebe, Ivana Grabundzija, Sylvia Merkert, Patricia Gerdes, J. Andres Pulgarin, Anja Bock, Ulrike Held, Anett Witthuhn, Alexandra Haase, Balázs Sarkadi, Johannes Löwer, Ernst J. Wolvetang, Ulrich Martin, Zoltán Ivics, Zsuzsanna Izsvák, Jose L. Garcia-Perez, Geoffrey J. Faulkner, Gerald G. Schumann
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
Genetic and epigenetic abnormalities have been found to result from reprogramming of differentiated cells into human induced pluripotent stem cells (hiPSCs). Here, Klawitter et al.identify endogenous L1, Alu and SVA mobilization during reprogramming,
Externí odkaz:
https://doaj.org/article/c3ef18eb5c21445d985ad18b9ff23d87
Autor:
Marie MacLennan, Marta García-Cañadas, Judith Reichmann, Elena Khazina, Gabriele Wagner, Christopher J Playfoot, Carmen Salvador-Palomeque, Abigail R Mann, Paula Peressini, Laura Sanchez, Karen Dobie, David Read, Chao-Chun Hung, Ragnhild Eskeland, Richard R Meehan, Oliver Weichenrieder, Jose Luis García-Pérez, Ian R Adams
Publikováno v:
eLife, Vol 6 (2017)
Mobilization of retrotransposons to new genomic locations is a significant driver of mammalian genome evolution, but these mutagenic events can also cause genetic disorders. In humans, retrotransposon mobilization is mediated primarily by proteins en
Externí odkaz:
https://doaj.org/article/0409e8beef6843779f7cbc72c6456fd6
Autor:
Sabine Klawitter, Nina V. Fuchs, Kyle R. Upton, Martin Muñoz-Lopez, Ruchi Shukla, Jichang Wang, Marta Garcia-Cañadas, Cesar Lopez-Ruiz, Daniel J. Gerhardt, Attila Sebe, Ivana Grabundzija, Sylvia Merkert, Patricia Gerdes, J. Andres Pulgarin, Anja Bock, Ulrike Held, Anett Witthuhn, Alexandra Haase, Balázs Sarkadi, Johannes Löwer, Ernst J. Wolvetang, Ulrich Martin, Zoltán Ivics, Zsuzsanna Izsvák, Jose L. Garcia-Perez, Geoffrey J. Faulkner, Gerald G. Schumann
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-1 (2018)
This Article contains an error in the author affiliations. The correct affiliation for author Ruchi Shukla is ‘MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Crewe Road, Edinburgh, EH4 2XU, UK’, an
Externí odkaz:
https://doaj.org/article/73f8a71f8e3443d1af99aa1de2e348c3
Autor:
Kevin C. L. Cheng, Jennifer M. Frost, Francisco J. Sánchez-Luque, Marta García-Canãdas, Darren Taylor, Wan R. Yang, Branavy Irayanar, Swetha Sampath, Hemalvi Patani, Karl Agger, Kristian Helin, Gabriella Ficz, Kathleen H. Burns, Adam Ewing, José L. García-Pérez, Miguel R. Branco
Publikováno v:
Epigenetics & Chromatin, Vol 16, Iss 1, Pp 1-16 (2023)
Abstract Background Vitamin C (vitC) enhances the activity of 2-oxoglutarate-dependent dioxygenases, including TET enzymes, which catalyse DNA demethylation, and Jumonji-domain histone demethylases. The epigenetic remodelling promoted by vitC improve
Externí odkaz:
https://doaj.org/article/f795feb9ee214159af694527040dae95
Autor:
Manvendra Singh, Aleksandra M Kondrashkina, Thomas J Widmann, Jose L Cortes, Vikas Bansal, Jichang Wang, Christine Römer, Marta Garcia-Canadas, Jose L Garcia-Perez, Laurence D Hurst, Zsuzsanna Izsvák
Publikováno v:
PLoS Biology, Vol 21, Iss 6, p e3002162 (2023)
There remains much that we do not understand about the earliest stages of human development. On a gross level, there is evidence for apoptosis, but the nature of the affected cell types is unknown. Perhaps most importantly, the inner cell mass (ICM),
Externí odkaz:
https://doaj.org/article/124c7b6fd472479b998f8d9697af54ad
Autor:
Manvendra Singh, Aleksandra M. Kondrashkina, Thomas J. Widmann, Jose L. Cortes, Vikas Bansal, Jichang Wang, Christine Römer, Marta Garcia-Canadas, Jose L. Garcia-Perez, Laurence D. Hurst, Zsuzsanna Izsvák
Publikováno v:
PLoS Biology, Vol 21, Iss 6 (2023)
There remains much that we do not understand about the earliest stages of human development. On a gross level, there is evidence for apoptosis, but the nature of the affected cell types is unknown. Perhaps most importantly, the inner cell mass (ICM),
Externí odkaz:
https://doaj.org/article/c79ae257f97a464eb8488ff58e3fdc6f