Pd(II)-Catalyzed Fujiwara–Moritani Reactions for the Synthesis and Functionalization of Substituted Coumarins

Autor: Verónica Ortiz-de-Elguea, Asier Carral-Menoyo, Lorena Simón-Vidal, Mikel Martinez-Nunes, Iratxe Barbolla, Marta G. Lete, Nuria Sotomayor, Esther Lete

Publikováno v: ACS Omega, Vol 6, Iss 44, Pp 29483-29494 (2021)

Externí odkaz: https://doaj.org/article/4f7124a2a6ff4aada79c0628dbe796ec

Molecular Recognition of Glycan-Bearing Glycomacromolecules Presented at Membrane Surfaces by Lectins: An NMR View

Autor: Marta G. Lete, Miriam Hoffmann, Nils Schomann, Ane Martínez-Castillo, Francesca Peccati, Patrick B. Konietzny, Sandra Delgado, Nicole L. Snyder, Gonzalo Jiménez-Oses, Nicola G. A. Abrescia, Ana Ardá, Laura Hartmann, Jesús Jiménez-Barbero

Lectin–glycan interactions are at the heart of a multitude of biological events. Glycans are usually presented in a multivalent manner on the cell surface as part of the so-called glycocalyx, where they interact with other entities. This multivalen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9898900c708674a1b02b666b6abbd754
http://hdl.handle.net/10810/61927

Pd(II)-Catalyzed Fujiwara–Moritani Reactions for the Synthesis and Functionalization of Substituted Coumarins

Autor: Marta G. Lete, Nuria Sotomayor, Asier Carral-Menoyo, Iratxe Barbolla, Mikel Martinez-Nunes, Verónica Ortiz-de-Elguea, Esther Lete, Lorena Simón-Vidal

Publikováno v: ACS Omega, Vol 6, Iss 44, Pp 29483-29494 (2021)
ACS Omega
Addi. Archivo Digital para la Docencia y la Investigación
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Highly substituted coumarins, privileged and versatile scaffolds for bioactive natural products and fluorescence imaging, are obtained via a Pd(II)-catalyzed direct C-H alkenylation reaction (Fujiwara-Moritani reaction), which has emerged as a powerf

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eda7f107c266df417df5bc7577075818
https://doaj.org/article/4f7124a2a6ff4aada79c0628dbe796ec

Synthetic zwitterionic streptococcus pneumoniae Type 1 oligosaccharides carrying labile O-acetyl esters

Autor: Zhen Wang, Ana Gimeno, Marta G. Lete, Herman S. Overkleeft, Gijsbert A. van der Marel, Fabrizio Chiodo, Jesús Jiménez‐Barbero, Jeroen D. C. Codée

Publikováno v: Angewandte Chemie (International Edition), 62(1):e202211940
Angewandte Chemie-International Edition, 62(1):e202211940. John Wiley and Sons Ltd
Wang, Z, Gimeno, A, Lete, M G, Overkleeft, H S, van der Marel, G A, Chiodo, F, Jiménez-Barbero, J & Codée, J D C 2023, ' Synthetic Zwitterionic Streptococcus pneumoniae Type 1 Oligosaccharides Carrying Labile O-Acetyl Esters ', Angewandte Chemie-International Edition, vol. 62, no. 1, e202211940 . https://doi.org/10.1002/anie.202211940

We herein report the first total synthesis of the Streptococcus pneumoniae serotype 1 (Sp1) oligosaccharide, a unique zwitterionic capsular polysaccharide carrying labile O-acetyl esters. The target oligosaccharides, featuring rare α-2,4-diamino-2,4

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::473dd042b79b360b428af14157093822
http://hdl.handle.net/1887/3562958

Lipid transfer proteins and instructive regulation of lipid kinase activities: Implications for inositol lipid signaling and disease

Autor: Marta G. Lete, Vijay Chandran, Vytas A. Bankaitis, Mark I. McDermott, Ashutosh Tripathi

Publikováno v: Adv Biol Regul

Cellular membranes are critical platforms for intracellular signaling that involve complex interfaces between lipids and proteins, and a web of interactions between a multitude of lipid metabolic pathways. Membrane lipids impart structural and functi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdb0dfbb52e605b54ff191b6636606f4
https://pubmed.ncbi.nlm.nih.gov/32992233