Lifetime prevalence of owner-reported medical conditions in the 25 most common dog breeds in the Dog Aging Project pack

Autor: Kiersten K. Forsyth, Brianah M. McCoy, Sarah M. Schmid, Daniel E. L. Promislow, Noah Snyder-Mackler, the DAP Consortium, Joshua M. Akey, Brooke Benton, Elhanan Borenstein, Marta G. Castelhano, Amanda E. Coleman, Kate E. Creevy, Kyle Crowder, Matthew D. Dunbar, Virginia R. Fajt, Annette L. Fitzpatrick, Unity Jeffery, Erica C Jonlin, Matt Kaeberlein, Elinor K. Karlsson, Kathleen F. Kerr, Jonathan M. Levine, Jing Ma, Robyn L McClelland, Audrey Ruple, Stephen M. Schwartz, Sandi Shrager, M. Katherine Tolbert, Silvan R. Urfer, Benjamin S. Wilfond

Publikováno v: Frontiers in Veterinary Science, Vol 10 (2023)

IntroductionLarge scale data on the prevalence of diverse medical conditions among dog breeds in the United States are sparse. This cross-sectional study sought to estimate the lifetime prevalence of medical conditions among US dogs and to determine

Externí odkaz: https://doaj.org/article/364df0fc30b3463485ed60d13efb7929

Demographic factors associated with joint supplement use in dogs from the Dog Aging Project

Autor: Jessica M. Hoffman, M. Katherine Tolbert, Daniel E. L. Promislow, The Dog Aging Project Consortium, Joshua M Akey, Brooke Benton, Elhanan Borenstein, Marta G Castelhano, Amanda E Coleman, Kate E Creevy, Kyle Crowder, Matthew D Dunbar, Virginia R Fajt, Annette L Fitzpatrick, Unity Jeffery, Erica C Jonlin, Matt Kaeberlein, Elinor K Karlsson, Kathleen F Kerr, Jonathan M Levine, Jing Ma, Robyn L McClelland, Audrey Ruple, Stephen M Schwartz, Sandi Shrager, Noah Snyder-Mackler, Silvan R Urfer, Benjamin S Wilfond

Publikováno v: Frontiers in Veterinary Science, Vol 9 (2022)

Osteoarthritis (OA) is one of the most prevalent age-related chronic conditions that afflict companion dogs, and multiple joint supplements are available to prevent or treat OA, though the efficacy of these treatments is controversial. While the demo

Externí odkaz: https://doaj.org/article/fa849b279a3a4e0784fe4481a3c81bdd

Priorities in Biobanking Research: A Report on the 2021 ISBER Round Table

Autor: Jennifer A. Byrne, Anastazia T. Banaszak, Jane E. Carpenter, Steven L. Carroll, Marta G. Castelhano, Paula S. Espinal, Marianne K. Henderson, Anusha Hettiaratchi, Mantombi Maseme, Wayne Ng, Kirtika Patel, Iuliana Popescu, Sergio I. Prada, William S. Schleif, Miranda Smith, Shirley Wee, Carol J. Weil, Katherine Woods

Publikováno v: Biopreservation and Biobanking. 21:111-113

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18bf14ef82d05dcb92863fedbf76c45d
https://doi.org/10.1089/bio.2021.0178

Imputation of canine genotype array data using 365 whole-genome sequences improves power of genome-wide association studies.

Autor: Jessica J Hayward, Michelle E White, Michael Boyle, Laura M Shannon, Margret L Casal, Marta G Castelhano, Sharon A Center, Vicki N Meyers-Wallen, Kenneth W Simpson, Nathan B Sutter, Rory J Todhunter, Adam R Boyko

Publikováno v: PLoS Genetics, Vol 15, Iss 9, p e1008003 (2019)

Genomic resources for the domestic dog have improved with the widespread adoption of a 173k SNP array platform and updated reference genome. SNP arrays of this density are sufficient for detecting genetic associations within breeds but are underpower

Externí odkaz: https://doaj.org/article/1b3b0967a4904b48ab1f842bd11f8123

Mutations in the Kinesin-2 Motor KIF3B Cause an Autosomal-Dominant Ciliopathy

Autor: Julia H. Wildschutte, Marta G. Castelhano, Max F. Rothschild, Maria Kaukonen, Georgios Kellaris, Joshua A. Stern, Stéphane Bézieau, Laurence Legeai-Mallet, Shrinivas P. Mane, Dominique Debray, Hannes Lohi, Ottmar Distl, Laurence M. Occelli, Kinga M. Bujakowska, Marjo K. Hytönen, Oliver P. Forman, Elizabeth A. Wilcox, Richard Malik, Tosso Leeb, Ronald H.L. Li, Elizabeth L. Cadena, William F. Swanson, Teri L. Lear, Yoshihiko Yu, Robert J. Harvey, Dominique Caldari, Erica E. Davis, Bianca Haase, Eric A. Pierce, Reuben M. Buckley, Stephen P. Daiger, L. Martin, D. Aberdein, Clare Rusbridge, Simon M. Petersen-Jones, Edward I. Ginns, Daniel C. Koboldt, Benjamin Cogné, Lokuliyanage Dona Samudita Senaratne, Michael B. Gorin, Niels C Pedersen, Margret L. Casal, Xenia Latypova, Adam R. Boyko, Isabel Hernandez, Tomoki Kosho, Sara J. Bowne, Nicholas H. Dodman, Tomas F. Bergström, Nicholas Katsanis, Rebecca R. Bellone, Guylène Le Meur, Bertrand Isidor, Daisuke Hasegawa, Christopher B. Kaelin, Mathilde Nizon, Karen A. Terio, Paulo C. Alves, Leslie A. Lyons, Christopher R Helps, Eirik Frengen, Emilie Leclerc, William J. Murphy, Beth Shapiro, Mark A. Magnuson, Lorraine Fievet, Maria Longeri, Rory J. Todhunter, Jeffrey A. Brockman, Lori S. Sullivan, Dorian J. Garrick, Jens Häggström, Jonathan E. Fogle, N. Matthew Ellinwood, Wesley C. Warren, John S. Munday, Gregory S. Barsh

Publikováno v: American Journal of Human Genetics
American Journal of Human Genetics, Elsevier (Cell Press), 2020, 106, pp.893-904. ⟨10.1016/j.ajhg.2020.04.005⟩
Am J Hum Genet

Kinesin-2 enables ciliary assembly and maintenance as an anterograde intraflagellar transport (IFT) motor. Molecular motor activity is driven by a heterotrimeric complex comprised of KIF3A and KIF3B or KIF3C plus one non-motor subunit, KIFAP3. Using

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a48a8e4787ee74d7e392a0a9500b3f4d
https://hal.archives-ouvertes.fr/hal-03490699