Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Marta E. Stremska"'
Autor:
Michael S. Schappe, Marta E. Stremska, Gregory W. Busey, Taylor K. Downs, Philip V. Seegren, Suresh K. Mendu, Zachary Flegal, Catherine A. Doyle, Eric J. Stipes, Bimal N. Desai
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Efficient removal of apoptotic cells by phagocytosis underlies tissue development, wound repair, host defense and organ homeostasis. Here, authors identify TRPM7 as a regulator of cargo acidification and Ca2+ signaling during apoptotic cell clearance
Externí odkaz:
https://doaj.org/article/91b4d7f5e2564ec69283f69be2f00ae0
Autor:
Vikram Sabapathy, Marta E. Stremska, Saleh Mohammad, Rebecca L. Corey, Poonam R. Sharma, Rahul Sharma
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Obesity-linked (type 2) diabetic nephropathy (T2DN) has become the largest contributor to morbidity and mortality in the modern world. Recent evidences suggest that inflammation may contribute to the pathogenesis of T2DN and T-regulatory cells (Treg)
Externí odkaz:
https://doaj.org/article/0bd7776d396c40cb8eba3b4839dcd48a
Autor:
Marta E. Stremska, Vikram Sabapathy, Sheethal Jose, Rahul Sharma, Chao Dai, Sun-Sang J. Sung, Shu Man Fu, Gaurav Kumar, Hongyang Wang, Rajkumar Venkatadri, Saleh Mohammad
Publikováno v:
J Autoimmun
Lupus glomerulonephritis (GN) is an autoimmune disease characterized by immune complex-deposition, complement activation and glomerular inflammation. In lupus-prone NZM2328 mice, the occurrence of lupus GN was accompanied by a decrease in Treg cells
Autor:
Suresh K. Mendu, Marta E. Stremska, Bimal N. Desai, Julia K. Krupa, Clare A. Parker, Michael S. Schappe, Eric J. Stipes, Jason S. Rogers, Justin S. A. Perry, Emily K. Moser, Thomas J. Braciale
Publikováno v:
Sci Signal
The thymic development of regulatory T (T(reg)) cells, crucial suppressors of the responses of effector T (T(eff)) cells, is governed by the transcription factor FOXP3. Despite the clinical importance of T(reg) cells, there is a dearth of druggable m
Autor:
Christopher B. Medina, Ivan K. H. Poon, Yu-Hsin Chiu, Ulrike Lorenz, Kenneth S. K. Tung, Marta E. Stremska, Kodi S. Ravichandran, Christopher D. Lucas, Douglas A. Bayliss, Bimal N. Desai, Michael R. Elliott
Publikováno v:
Medina, C B, Chiu, Y-H, Stremska, M E, Lucas, C D, Poon, I, Tung, K S, Elliott, M R, Desai, B, Bayliss, D A, Lorenz, U M & Ravichandran, K S 2021, ' Pannexin 1 channels facilitate communication between T cells to restrict the severity of airway inflammation ', Immunity . https://doi.org/10.1016/j.immuni.2021.06.014
IMMUNITY
Immunity
IMMUNITY
Immunity
Allergic airway inflammation affects millions of people world-wide. Among the many factors affecting airway inflammation, type 2 inflammatory responses coordinated by CD4+ T cells are important in disease progression. Pannexins are plasma membrane ch
Autor:
Michael S, Schappe, Marta E, Stremska, Gregory W, Busey, Taylor K, Downs, Philip V, Seegren, Suresh K, Mendu, Zachary, Flegal, Catherine A, Doyle, Eric J, Stipes, Bimal N, Desai
Publikováno v:
Nature communications. 13(1)
Efficient clearance of apoptotic cells by phagocytosis, also known as efferocytosis, is fundamental to developmental biology, organ physiology, and immunology. Macrophages use multiple mechanisms to detect and engulf apoptotic cells, but the signalin
Autor:
Poonam Sharma, Vikram Sabapathy, Rebecca L. Corey, Saleh Mohammad, Rahul Sharma, Marta E. Stremska
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Frontiers in Pharmacology
Frontiers in Pharmacology
Obesity-linked (type 2) diabetic nephropathy (T2DN) has become the largest contributor to morbidity and mortality in the modern world. Recent evidences suggest that inflammation may contribute to the pathogenesis of T2DN and T-regulatory cells (Treg)
Autor:
Marta E. Stremska, Taylor K Downs, Rachel J. Olson, Ammasi Periasamy, Joel Kennedy, Philip V. Seegren, Logan R. Harper, Norbert Leitinger, Catherine A. Doyle, Eric L. Stipes, Clint M Upchurch, Bimal N. Desai, Ruofan Cao
Publikováno v:
Cell reports
SUMMARY Phagocytes reallocate metabolic resources to kill engulfed pathogens, but the intracellular signals that rapidly switch the immunometabolic program necessary to fuel microbial killing are not understood. We report that macrophages use a fast
Autor:
Poonam Sharma, Vikram Sabapathy, Amandeep Bajwa, Rahul Sharma, Saleh Mohammad, Diane L. Rosin, Liping Huang, Mark D. Okusa, Gilbert R. Kinsey, Marta E. Stremska, Sheethal Jose
CD4+Foxp3+ regulatory T cells (Tregs) protect the kidney during AKI. We previously found that IL-2, which is critical for Treg homeostasis, upregulates the IL-33 receptor (ST2) on CD4+ T cells, thus we hypothesized that IL-2 and IL-33 cooperate to en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a293f4f4af8d8713dbab277c69569c84
https://europepmc.org/articles/PMC5576940/
https://europepmc.org/articles/PMC5576940/
Autor:
Michael S, Schappe, Kalina, Szteyn, Marta E, Stremska, Suresh K, Mendu, Taylor K, Downs, Philip V, Seegren, Michelle A, Mahoney, Sumeet, Dixit, Julia K, Krupa, Eric J, Stipes, Jason S, Rogers, Samantha E, Adamson, Norbert, Leitinger, Bimal N, Desai
Publikováno v:
Immunity. 48(1)
Toll-like receptors (TLRs) sense pathogen-associated molecular patterns to activate the production of inflammatory mediators. TLR4 recognizes lipopolysaccharide (LPS) and drives the secretion of inflammatory cytokines, often contributing to sepsis. W