Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Marta E. Bull"'
Autor:
Claire N. Levy, Sean M. Hughes, Pavitra Roychoudhury, Daniel B. Reeves, Chelsea Amstuz, Haiying Zhu, Meei-Li Huang, Yulun Wei, Marta E. Bull, Noah A.J. Cassidy, Jan McClure, Lisa M. Frenkel, Mars Stone, Sonia Bakkour, Elizabeth R. Wonderlich, Michael P. Busch, Steven G. Deeks, Joshua T. Schiffer, Robert W. Coombs, Dara A. Lehman, Keith R. Jerome, Florian Hladik
Publikováno v:
Cell Reports Medicine, Vol 2, Iss 4, Pp 100243- (2021)
Summary: Quantifying the replication-competent HIV reservoir is essential for evaluating curative strategies. Viral outgrowth assays (VOAs) underestimate the reservoir because they fail to induce all replication-competent proviruses. Single- or doubl
Externí odkaz:
https://doaj.org/article/ca3fdb99e1bc4cce8f4299809e25a852
Autor:
Robert W. Coombs, Marta E Bull, Tajanna Stinn, Steve Kuntz, Meei-Li Huang, Samuel Njikan, Christine Johnston, Stacy Selke, Emily S Ford, Joan Dragavon, Dana Varon
Publikováno v:
J Virol
Antigen (Ag)-specific immune responses to chronic infections, such as herpes simplex virus type 2 (HSV-2) in HIV/HSV-coinfected persons, may sustain HIV tissue reservoirs by promoting T-cell proliferation but are poorly studied in women on antiretrov
Autor:
Elizabeth R. Wonderlich, Jan McClure, Haiying Zhu, Robert W. Coombs, Sean M. Hughes, Keith R. Jerome, Mars Stone, Marta E. Bull, Noah A. Cassidy, Florian Hladik, Lisa M. Frenkel, Daniel B. Reeves, Pavitra Roychoudhury, Yulun Wei, Joshua T. Schiffer, Chelsea Amstuz, Sonia Bakkour, Michael P. Busch, Claire N. Levy, Dara A. Lehman, Meei-Li Huang, Steven G. Deeks
Publikováno v:
Cell Reports Medicine
Cell Reports Medicine, Vol 2, Iss 4, Pp 100243-(2021)
Cell reports. Medicine, vol 2, iss 4
Cell Reports Medicine, Vol 2, Iss 4, Pp 100243-(2021)
Cell reports. Medicine, vol 2, iss 4
Summary Quantifying the replication-competent HIV reservoir is essential for evaluating curative strategies. Viral outgrowth assays (VOAs) underestimate the reservoir because they fail to induce all replication-competent proviruses. Single- or double
Autor:
Kessara Pathanapitoon, Lisa M. Frenkel, Paradee Kunavisarut, Nicole Ngo-Giang-Huong, Natedao Kongyai, Tanawan Samleerat, Corey A. Williams-Wietzikoski, Marta E. Bull, Wasna Sirirungsi, Isaac So
Publikováno v:
AIDS. 31:1825-1830
Objective To analyze and compare HIV-1 env sequences from the eye to those from the blood of individuals with uveitis attributed to HIV with the goal of gaining insight into the pathogenesis of HIV-associated eye disease. Design A prospective case se
Autor:
Sarah Holte, Wenjie Deng, James I. Mullins, Lisa M. Frenkel, Jennifer L. McKernan, Kelli Kraft, Marta E. Bull, Sheila Styrchak, Robert W. Coombs, Jane Hitti, Susan E. Cohn, Kenneth Tapia
Publikováno v:
AIDS Res Hum Retroviruses
Identifying tissue sources of HIV that rebound following “failure” of antiretroviral therapy (ART) is critical to evaluating cure strategies. To assess the role of the uterine cervix and peripheral blood mononuclear cells (PBMC) as viral reservoi
Autor:
Kelli Kraft, Edward P. Acosta, Alberto La Rosa, Sarah Holte, Kevin J. Ryan, Sheila Styrchak, Jaime Soria, Corey A. Williams-Wietzikoski, Caroline M. Mitchell, Marta E. Bull, Eduardo Ticona, Jillian Legard, Lisa M. Frenkel, Jennifer McKernan-Mullin, Joshua E. Stern, Robert W. Coombs, Frankline Onchiri
Publikováno v:
AIDS (London, England)
Objective: During effective antiretroviral therapy (ART), low-level plasma viremias (LLV) (HIV RNA >30–1000 copies/ml) can be detected intermittently. We hypothesized that systemic inflammation is associated with LLV either as the cause or result o
Autor:
Robert W. Coombs, Jane Hitti, Marta E. Bull, Bess Sorensen, Jillian Legard, Susan E. Cohn, Rochelle L. Garcia, Kenneth Tapia, Sarah Holte
Publikováno v:
JAIDS Journal of Acquired Immune Deficiency Syndromes. 67:357-364
Background HIV-1 shedding from the female genital tract is associated with increased sexual and perinatal transmission and has been broadly evaluated in cross-sectional studies. However, few longitudinal studies have evaluated how the immune microenv
Autor:
Lisa M. Frenkel, Robert W. Coombs, Jennifer McKernan-Mullin, Kelli Kraft, Laura Heath, Jane Hitti, Susan E. Cohn, Marta E. Bull, Luis Acevedo, Sarah Holte, James I. Mullins, Kenneth Tapia, Joan Dragavon
Publikováno v:
The Journal of Infectious Diseases. 207:1206-1215
Whether human immunodeficiency virus (HIV) in the female genital tract constitutes a genetically distinct compartment from the blood remains an important question, with both clinical and biologic implications because of the role of the genital tract
Autor:
Ingrid A. Beck, Lisa M. Frenkel, Jennifer McKernan-Mullin, Paul Krogstad, Minyoung Jang, Sharon Nachman, Marta E. Bull, Susan H. Eshleman, Sharon Huang, Andrew Wiznia, Lin Ye Song, Thor A. Wagner
Publikováno v:
AIDS Research and Human Retroviruses. 28:780-788
Our objective was to determine whether monitoring HIV-1 DNA concentration or new resistance mutations in peripheral blood mononuclear cells (PBMCs) during effective antiretroviral therapy (ART) predicts virologic failure. A retrospective analysis use
Autor:
Lisa M. Frenkel, Alberto La Rosa, Sandra Dross, Caroline M. Mitchell, Marta E. Bull, Eduardo Ticona, Robert W. Coombs, Kelli Kraft, Jaime Soria
Publikováno v:
AIDS Research and Human Retroviruses. 28:333-338
Transmission of drug-resistant HIV (TDR) has been associated with virologic failure of "first-line," nonnucleoside reverse transcriptase inhibitor (NNRTI)-based antiretroviral therapy (ART). A national ART program began in Peru in 2004. We evaluated