Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Marta E Polak"'
Autor:
Aymen Al-Shamkhani, Marta E Polak, Pauline Rettman, Matthew D Blunt, Rebecca J Fulton, Andres F Vallejo, Leidy Y Bastidas-Legarda, Laura España-Serrano, Christelle Retiere, Salim I Khakoo
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 5 (2021)
Background Natural killer (NK) cells are increasingly being recognized as agents for cancer immunotherapy. The killer cell immunoglobulin-like receptors (KIRs) are expressed by NK cells and are immunogenetic determinants of the outcome of cancer. In
Externí odkaz:
https://doaj.org/article/ace849bd921c4f8a8075efbe163b9ccb
Autor:
Sofia Sirvent, Andres F. Vallejo, Emma Corden, Ying Teo, James Davies, Kalum Clayton, Eleanor G. Seaby, Chester Lai, Sarah Ennis, Rfeef Alyami, Gemma Douilhet, Lareb S. N. Dean, Matthew Loxham, Sarah Horswill, Eugene Healy, Graham Roberts, Nigel J. Hall, Peter S. Friedmann, Harinder Singh, Clare L. Bennett, Michael R Ardern-Jones, Marta E. Polak
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Regulation of cutaneous immunity is severely compromised in inflammatory skin disease. To investigate the molecular crosstalk underpinning tolerance versus inflammation in atopic dermatitis, we utilise a human in vivo allergen challenge stud
Externí odkaz:
https://doaj.org/article/8a9e3b6f395949309fb497cf8ddaabc0
Autor:
Leilane Oliveira Gonçalves, Andrés F. Vallejo Pulido, Fernando Augusto Siqueira Mathias, Alexandre Estevão Silvério Enes, Maria Gabriela Reis Carvalho, Daniela de Melo Resende, Marta E. Polak, Jeronimo C. Ruiz
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Leishmania amazonensis and Leishmania major are the causative agents of cutaneous and mucocutaneous diseases. The infections‘ outcome depends on host–parasite interactions and Th1/Th2 response, and in cutaneous form, regulation of Th17 cytokines
Externí odkaz:
https://doaj.org/article/63f8b76b136e447eb52c9620b10e1355
Autor:
Heather C. West, James Davies, Stephen Henderson, Oluyori K. Adegun, Sophie Ward, Ivana R. Ferrer, Chanidapa A. Tye, Andres F. Vallejo, Laura Jardine, Matthew Collin, Marta E. Polak, Clare L. Bennett
Publikováno v:
Cell Reports, Vol 39, Iss 7, Pp 110819- (2022)
Summary: T cell pathology in the skin leads to monocyte influx, but we have little understanding of the fate of recruited cells within the diseased niche, or the long-term impact on cutaneous immune homeostasis. By combining a murine model of acute g
Externí odkaz:
https://doaj.org/article/960eba7bb8e8431f8c5a9ff4e7e81b08
Autor:
Jelmer Legebeke, Jenny Lord, Rebekah Penrice-Randal, Andres F. Vallejo, Stephen Poole, Nathan J. Brendish, Xiaofeng Dong, Catherine Hartley, John W. Holloway, Jane S. Lucas, Anthony P. Williams, Gabrielle Wheway, Fabio Strazzeri, Aaron Gardner, James P. R. Schofield, Paul J. Skipp, Julian A. Hiscox, Marta E. Polak, Tristan W. Clark, Diana Baralle
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The worldwide COVID-19 pandemic has claimed millions of lives and has had a profound effect on global life. Understanding the body’s immune response to SARS-CoV-2 infection is crucial in improving patient management and prognosis. In this study we
Externí odkaz:
https://doaj.org/article/f46b555a1c314f3fb50bd6cabe819aa8
Autor:
Adam P Dale, Anastasia A Theodosiou, Diane F Gbesemete, Jonathan M Guy, Eleanor F Jones, Alison R Hill, Muktar M Ibrahim, Hans de Graaf, Muhammad Ahmed, Saul N Faust, Andrew R Gorringe, Marta E Polak, Jay R Laver, Robert C Read
Publikováno v:
The Lancet Microbe. 3:e931-e943
Pharyngeal colonisation by the commensal bacterium Neisseria lactamica inhibits colonisation by Neisseria meningitidis and has an inverse epidemiological association with meningococcal disease. The mechanisms that underpin this relationship are uncle
Autor:
Theresa J. Hydes, Matthew D. Blunt, Jennifer Naftel, Andres F. Vallejo, Grégory Seumois, Alice Wang, Pandurangan Vijayanand, Marta E. Polak, Salim I. Khakoo
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Natural killer (NK) cells are innate immune cells that interface with the adaptive immune system to generate a pro-inflammatory immune environment. Primary Biliary Cholangitis (PBC) is a hepatic autoimmune disorder with extrahepatic associations incl
Externí odkaz:
https://doaj.org/article/2b014133bbf04acaa750cbfc5f905fdc
Autor:
Eugene Healy, Aymen Al-Shamkhani, Martin J. Glennie, Ruth R. French, Amanda S. MacLeod, Jeffrey Theaker, Marta E. Polak, Shin-Young Cho, Ramnik Behar, Amel Albibas, Suzannah August, Chester Lai
Supplementary figure 2: CLA is expressed by tumoral T cells and Tregs in cSCCs.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::729b33b682157b2e61e8cb61b9d67513
https://doi.org/10.1158/1078-0432.22456355
https://doi.org/10.1158/1078-0432.22456355
Autor:
Eugene Healy, Aymen Al-Shamkhani, Martin J. Glennie, Ruth R. French, Amanda S. MacLeod, Jeffrey Theaker, Marta E. Polak, Shin-Young Cho, Ramnik Behar, Amel Albibas, Suzannah August, Chester Lai
Supplementary figure 4: cSCC blood vessels express e-selectin.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::674b8399a33338c1f83ef9a93f5b6525
https://doi.org/10.1158/1078-0432.22456349.v1
https://doi.org/10.1158/1078-0432.22456349.v1
Autor:
Eugene Healy, Aymen Al-Shamkhani, Martin J. Glennie, Ruth R. French, Amanda S. MacLeod, Jeffrey Theaker, Marta E. Polak, Shin-Young Cho, Ramnik Behar, Amel Albibas, Suzannah August, Chester Lai
Supplementary figure 6: Comparison of FOXP3+ Treg frequencies between well differentiated cSCCs (G1) and moderately or poorly differentiated cSCCs (G2-3).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc33b73bdb2a7c4b4f537a2417bf3825
https://doi.org/10.1158/1078-0432.22456343.v1
https://doi.org/10.1158/1078-0432.22456343.v1