Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Marta Dratwa"'
Autor:
Marta Dratwa-Kuzmin, Bushra Al Hadra, Fatma Oguz, Yeliz Ogret, Ileana Constantinescu, Dimitri Apostol, Adriana Talangescu, Alexandra-Elena Constantinescu, Ion Maruntelu, Katarzyna Kościńska, Tsvetelin Lukanov, Elissaveta Naumova, Katarzyna Bogunia-Kubik
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 17, p 9457 (2024)
Aging is an exceptionally complex process that depends on genetic, environmental, and lifestyle factors. Previous studies within the International HLA and Immunogenetics Workshop (IHIWS) component “Immunogenetics of Ageing” showed that longevity
Externí odkaz:
https://doaj.org/article/61b56e0acadc429ea9d3cc8d52bbb60a
Autor:
Marta Dratwa, Piotr Łacina, Aleksandra Butrym, Diana Porzuczek, Grzegorz Mazur, Katarzyna Bogunia-Kubik
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Telomere dysfunction is a notable event observed in many cancers contributing to their genomic instability. A major factor controlling telomere stability is the human telomerase reverse transcriptase catalytic subunit (hTERT). Telomere short
Externí odkaz:
https://doaj.org/article/257556e0756a4f61b055408e3b11b21f
Autor:
Karolina Piekarska, Marta Dratwa, Paweł Radwan, Michał Radwan, Katarzyna Bogunia-Kubik, Izabela Nowak
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Embryo implantation is a key moment in pregnancy. Abnormal production of pro- and anti-inflammatory cytokines, their receptors and other immune factors may result in embryo implantation failure and pregnancy loss. The aim of this study was to determi
Externí odkaz:
https://doaj.org/article/1f18d25d3a784d28a0aa837c5a86021d
Autor:
Marta Dratwa, Barbara Wysoczańska, Aleksandra Butrym, Piotr Łacina, Grzegorz Mazur, Katarzyna Bogunia-Kubik
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Acute myeloid leukaemia (AML) is a neoplasm of immature myeloid cells characterized by various cytogenetic alterations. The present study showed that in addition to the FLT3-ITD and NPM1 mutation status, telomere length (TL) and telomerase r
Externí odkaz:
https://doaj.org/article/11385e314e404688906129966ec49594
Autor:
Piotr Macek, Rafal Poreba, Pawel Gac, Katarzyna Bogunia-Kubik, Marta Dratwa, Mieszko Wieckiewicz, Anna Wojakowska, Monika Michalek-Zrabkowska, Grzegorz Mazur, Helena Martynowicz
Publikováno v:
Biomedicines, Vol 10, Iss 11, p 2755 (2022)
Introduction: Obstructive sleep apnea (OSA) is a worldwide breathing disorder that has been diagnosed globally in almost 1 billion individuals aged 30–69 years. It is characterized by repeated upper airway collapses during sleep. Telomerase reverse
Externí odkaz:
https://doaj.org/article/3aa5b9b8754040518f0422b49352c389
Autor:
Katarzyna Wicherska-Pawłowska, Katarzyna Bogunia-Kubik, Bartłomiej Kuszczak, Piotr Łacina, Marta Dratwa, Bożena Jaźwiec, Tomasz Wróbel, Justyna Rybka
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 17, p 9593 (2022)
Toll-like receptors (TLRs), NOD-like receptors (NLRs), and RIG-I-like receptors (RLRs) are major elements of the innate immune system that recognize pathogen-associated molecular patterns. Single-nucleotide polymorphisms (SNPs) in the TLR, NLR, and R
Externí odkaz:
https://doaj.org/article/5b519bfaaf7b489893fb777d4ef14940
Autor:
Marta Dratwa, Barbara Wysoczanska, Wioletta Brankiewicz, Martyna Stachowicz-Suhs, Joanna Wietrzyk, Rafał Matkowski, Marcin Ekiert, Jolanta Szelachowska, Adam Maciejczyk, Mariusz Szajewski, Maciej Baginski, Katarzyna Bogunia-Kubik
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 9, p 5164 (2022)
The molecular mechanisms of telomerase reverse transcriptase (TERT) upregulation in breast cancer (BC) are complex. We compared genetic variability within TERT and telomere length with the clinical data of patients with BC. Additionally, we assessed
Externí odkaz:
https://doaj.org/article/07bb022c63fe46f2b8d2af97677270c3
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Telomerase reverse transcriptase (TERT) is a catalytic subunit of telomerase. Telomerase complex plays a key role in cancer formation by telomere dependent or independent mechanisms. Telomere maintenance mechanisms include complex TERT changes such a
Externí odkaz:
https://doaj.org/article/e435fc00fba44b4699d99b45ccac4123
Autor:
Grzegorz Mazur, Marta Dratwa, Aleksandra Butrym, Piotr Łacina, Katarzyna Bogunia-Kubik, Barbara Wysoczańska
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Scientific Reports
Scientific Reports
Acute myeloid leukaemia (AML) is a neoplasm of immature myeloid cells characterized by various cytogenetic alterations. The present study showed that in addition to the FLT3-ITD and NPM1 mutation status, telomere length (TL) and telomerase reverse tr
Association of RANK and RANKL gene polymorphism with survival and calcium levels in multiple myeloma
Autor:
Aleksandra Butrym, Piotr Łacina, Grzegorz Mazur, Diana Frontkiewicz, Katarzyna Bogunia-Kubik, Marta Dratwa, Michał Humiński
Publikováno v:
Molecular Carcinogenesis. 60:106-112
Multiple myeloma (MM) is a heterogeneous bone marrow cancer characterized by proliferation of malignant plasma cells in the bone marrow. One of its major symptoms are hypercalcaemia and bone lesions, which may result in pathologic bone fractures. Rec