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Autor:
Francesco Gasparrini, Patrizia Simone, M.G. Quaglia, Fabrizio Giorgi, Marta Di Iorio, Andrea Mazzanti, Ilaria D'Acquarica, Walter Cabri, Marco Pierini, Michela Di Mattia, Claudio Villani
Publikováno v:
The Journal of Organic Chemistry. 76:4831-4840
Artemisinin or qinghaosu has now largely given way to the more potent dihydroartemisinin (DHA, 1) and its derivatives in the treatment of drug-resistant malaria, in combination with other classical antimalarial drugs. DHA is obtained by NaBH(4) reduc
Autor:
Patrizia Simone, Fabrizio Giorgi, Walter Cabri, Michela Di Mattia, Francesco Gasparrini, Ilaria D'acquarica, Andrea Mazzanti, Marco Pierini, M.G. Quaglia, Marta Di Iorio, Claudio Villani
Artemisinin (Qinghaosu, 1) is a sesquiterpene lactone endoperoxide isolated from Artemisia annua L. that Chinese herbalists have traditionally used to treat malaria. Reduction of artemisinin by NaBH(4) produced dihydroartemisinin (DHA, 2) and yielded
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b8b9a2d9af8481e0240dda5c28eb204
http://hdl.handle.net/11573/354195
http://hdl.handle.net/11573/354195