Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Marta Cecchi"'
Autor:
Laura Braconi, Chiara Riganti, Astrid Parenti, Marta Cecchi, Alessio Nocentini, Gianluca Bartolucci, Marta Menicatti, Marialessandra Contino, Nicola Antonio Colabufo, Dina Manetti, Maria Novella Romanelli, Claudiu T. Supuran, Elisabetta Teodori
Publikováno v:
Molecules, Vol 29, Iss 14, p 3290 (2024)
A new series of piperazine derivatives were synthesized and studied with the aim of obtaining dual inhibitors of P-glycoprotein (P-gp) and carbonic anhydrase XII (hCA XII) to synergistically overcome the P-gp-mediated multidrug resistance (MDR) in ca
Externí odkaz:
https://doaj.org/article/7f0fc90ebe6b4e25b07123ec416bb9e1
Autor:
Marta Cecchi, Cecilia Anceschi, Angela Silvano, Maria Luisa Coniglio, Aurora Chinnici, Lucia Magnelli, Andrea Lapucci, Anna Laurenzana, Astrid Parenti
Publikováno v:
Pharmaceuticals, Vol 17, Iss 5, p 558 (2024)
Background: Indoleamine 2,3-dioxygenase (IDO1) and tryptophan-2,3-dioxygenase (TDO) are the two principals enzymes involved in the catabolization of tryptophan (Trp) into kynurenine (Kyn). Despite their well-established role in the immune escape, the
Externí odkaz:
https://doaj.org/article/c027377be2114de097431b9153a87e88
Autor:
Marta Cecchi, Antonella Mannini, Andrea Lapucci, Angela Silvano, Matteo Lulli, Cristina Luceri, Mario D’Ambrosio, Alberto Chiarugi, Ali H. Eid, Astrid Parenti
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
In addition to its well-established immunosuppressive actions, tryptophan 2,3-dioxygenase (TDO) appears to elicit direct effects on tumor cell function. Although TDO has been associated with cancer stemness, its involvement in melanoma stem cell biol
Externí odkaz:
https://doaj.org/article/d3295c4230bc475687ce85da692dc7f2
Publikováno v:
Pharmaceuticals, Vol 14, Iss 3, p 211 (2021)
Tryptophan-2,3-dioxygenase (TDO) is one of the key tryptophan-catabolizing enzymes with immunoregulatory properties in cancer. Contrary to expectation, clinical trials showed that inhibitors of the ubiquitously expressed enzyme, indoleamine-2,3-dioxy
Externí odkaz:
https://doaj.org/article/837bb033f0404de39ae18850bec583ad
Autor:
Camilla Lugli, Marta Cecchini, Domenico Maione, Filomena Marseglia, Tommaso Filippini, Marco Vinceti, Elena Righi, Lucia Palandri, Daniela De Vita
Publikováno v:
Italian Journal of Food Safety (2024)
Foodborne diseases can be prevented by implementing a food safety system that manages food chain risks from producer to end-user, from a One Health perspective. In 2017, the European Parliament and the European Council adopted Regulation No. 625 on o
Externí odkaz:
https://doaj.org/article/7d470363492f4450865ac4e93034bc0f
Publikováno v:
Journal of Cancer Research and Clinical Oncology
Purpose Indoleamine 2,3-dioxygenase-1 (IDO1) and more recently, tryptophan 2,3-dioxygenase (TDO), are tryptophan-catabolizing enzymes with immunoregulatory properties in cancer. IDO1 is more expressed than TDO in many tumours including melanomas; how
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01f926f212fc31072864412b0c5d5c89
https://pubmed.ncbi.nlm.nih.gov/32776284
https://pubmed.ncbi.nlm.nih.gov/32776284
Autor:
Sara Paccosi, Marta Cecchi, Laura Pala, Astrid Parenti, Carlo Maria Rotella, Angela Silvano, Roberto Caporale, Barbara Cresci
Publikováno v:
Diabetes research and clinical practice. 170
Aim Cardiovascular disease (CVD) is prevalent in women after menopause, which may be associated with obesity, insulin resistance and metaflammation. Despite the recognized role of immunological mechanisms in vascular remodeling, the role of dendritic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd97e7c7aa5ad75b9782aba1409aabf3
https://pubmed.ncbi.nlm.nih.gov/33157116
https://pubmed.ncbi.nlm.nih.gov/33157116
Autor:
Marta Cecchi, Viola Seravalli, Enrico Tartarotti, Angela Silvano, Noemi Strambi, Astrid Parenti, Mariarosaria Di Tommaso
Publikováno v:
Journal of Reproductive Immunology. 147:103361
The placenta represents the maternal-fetal vascular interface. It is capable of supplying the bioenergetic needs of the developing conceptus. It is composed of different cell types that engage in highly varied functions, ranging from attachment, inva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad9b16058ad60f74ef9dd0d2d6eb23d5
https://doi.org/10.1016/j.jri.2021.103361
https://doi.org/10.1016/j.jri.2021.103361