Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Marta C. Yappert"'
Autor:
Slavyana Ivanova, Vesselin Tonchev, Norihiko Yokoi, Marta C. Yappert, Douglas Borchman, Georgi As. Georgiev
Publikováno v:
International Journal of Molecular Sciences, Vol 16, Iss 9, Pp 21813-21831 (2015)
Squalene (SQ) possesses a wide range of pharmacological activities (antioxidant, drug carrier, detoxifier, hydrating, emollient) that can be of benefit to the ocular surface. It can come in contact with human meibum (hMGS; the most abundant component
Externí odkaz:
https://doaj.org/article/34dc73460fed4e508e7e57ae7b8b105b
Autor:
Douglas Borchman, Marta C. Yappert
Publikováno v:
Journal of Lipid Research, Vol 51, Iss 9, Pp 2473-2488 (2010)
The unusually high levels of saturation and thus order contribute to the uniqueness of human lens membranes. In addition, and unlike in most biomembranes, most of the lens lipids are associated with proteins, thus reducing their mobility. The major p
Externí odkaz:
https://doaj.org/article/638f8d291d284bbb9b4ae06deb47beb9
Autor:
Samiyyah Sledge, Collin Henry, Douglas Borchman, Marta C. Yappert, Rahul Bhola, Aparna Ramasubramanian, Ryan Blackburn, Jonathan Austin, Kayla Massey, Shanzeh Sayied, Aliza Williams, Georgi Georgiev, Kenneth N. Schikler
Publikováno v:
International Journal of Molecular Sciences, Vol 18, Iss 9, p 1862 (2017)
Tear stability decreases with increasing age and the same signs of instability are exacerbated with dry eye. Meibum lipid compositional changes with age provide insights into the biomolecules responsible for tear film instability. Meibum was collecte
Externí odkaz:
https://doaj.org/article/858b5923241045a78d126b11bf50a4ae
Publikováno v:
Experimental eye research. 200
The causes of vitreous humor (VH) liquefaction remain unclear. Diabetes accelerates this process and other ocular diseases. The weakening of the blood-retina barrier observed with diabetes could enhance the rate of transfer of relatively small molecu
Autor:
Marta C. Yappert, Ryan Blackburn, Zahara N Gully, Douglas Borchman, Aakash Mehta, Sanya Mehta, Heegook Yeo, Sharika Singh, Samiyyah M. Sledge, Aparna Ramasubramanian
Publikováno v:
Cornea
PURPOSE: Meibum is considered to be a key component of tears which serve to protect the eye and conformational changes in meibum have not been studied extensively within the population of patients that had hematopoietic stem cell transplantation (HSC
Autor:
Marta C. Yappert, Aparna Ramasubramanian, Samiyyah M. Sledge, Ryan Blackburn, Douglas Borchman
Publikováno v:
The FASEB Journal. 32
Publikováno v:
Ophthalmic Research. 53:131-135
Background/Aims: It has been suggested that eye makeup could interact with human meibum causing a decrease in the stability of the tear film. The aim of this pilot study was to measure makeup-human meibum interactions in vitro. Methods: Human meibum-
Publikováno v:
Experimental eye research. 160
This project explores the regional phospholipid distribution in porcine vitreous humor, retina, and lens. Matrix-assisted laser desorption mass spectrometry has been used previously to image lipids, proteins, and other metabolites in retinas and lens
Autor:
Diana Duran, Marta C. Yappert, Gary R. Dennis, Ryan J. Smith, Gregory W. Cox, Poonam Mudgil, Douglas Borchman, John Whitehall, Rahul Bhola
Publikováno v:
Experimental Eye Research. 116:79-85
Tear film stability decreases with age however the cause(s) of the instability are speculative. Perhaps the more saturated meibum from infants may contribute to tear film stability. The meibum lipid phase transition temperature and lipid hydrocarbon
Publikováno v:
Lipids. 48:1269-1277
(1)H-NMR spectroscopy has been used to quantify squalene in meibum and sebum. Squalene has many beneficial properties and its loss on the surface of skin upon ultraviolet light exposure or in the tear film with dry eye could be detrimental. In this s