Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Marta C. Justino"'
Autor:
Fernanda Miguel, A. Raquel Baleizão, A. Gabriela Gomes, Helena Caria, Fátima N. Serralha, Marta C. Justino
Publikováno v:
BioTech, Vol 13, Iss 3, p 26 (2024)
Amidst the COVID-19 pandemic, the Polytechnic University of Setúbal (IPS) used its expertise in molecular genetics to establish a COVID-19 laboratory, addressing the demand for community-wide testing. Following standard protocols, the IPS COVID Lab
Externí odkaz:
https://doaj.org/article/933f2d6b30e34c0f9a5ef067ecc0d197
Publikováno v:
Biochemistry and Molecular Biology Education. 49:570-582
A computational biochemistry laboratory, fitted for bioinformatics students, is presented. The molecular dynamics package GROMACS is used to prepare and simulate a solvated protein. Students analyze the trajectory with different available tools (GROM
Autor:
Ana F Tavares, Margarida R Parente, Marta C Justino, Mónica Oleastro, Lígia S Nobre, Lígia M Saraiva
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e83157 (2013)
Helicobacter pylori is a pathogen that establishes long life infections responsible for chronic gastric ulcer diseases and a proved risk factor for gastric carcinoma. The therapeutic properties of carbon-monoxide releasing molecules (CORMs) led us to
Externí odkaz:
https://doaj.org/article/c86c72e6adee4f4491910a4b410c0f66
Autor:
Pedro C. Rosado, Maria de Fátima Montemor, Marta M. Alves, Karina Shimizu, Ricardo Meyrelles, Gonçalo C. Justino, Marta C. Justino, Ana M. Macatrão, Ana P. C. Ribeiro, A. Gabriela Gomes
Publikováno v:
Applied Surface Science. 537:147848
We report for the first time the use of NiO foams for specific protein binding. These affordable porous materials, with high surface area, possess the features required as supports for enzymatic catalysis. A physicochemical and computational characte
Publikováno v:
FEBS Journal. 281:4495-4505
Helicobacter pylori is a pathogen that infects the gastric mucosa of a large percentage of the human population worldwide, and predisposes to peptic ulceration and gastric cancer. Persistent colonization of humans by H. pylori triggers an inflammator
Publikováno v:
Antioxidants & Redox Signaling. 17:1190-1200
The ability of pathogens to cope with the damaging effects of nitric oxide (NO), present in certain host niches and produced by phagocytes that support innate immunity, relies on multiple strategies that include the action of detoxifying enzymes. As
Autor:
Gonçalo C. Justino, Pedro F. Pinheiro, M. Fernanda N. N. Carvalho, João Gonçalves, Alexandra P. S. Roseiro, Marta C. Justino, Ana S. O. Knittel
Publikováno v:
RSC Advances
The C–C chemokine receptor type 5 (CCR5) is a transmembrane receptor that plays a pivotal role as a HIV anchor to human cell membranes, mediating viral entry. CCR5 antagonists, acting by blocking the receptor and preventing its interaction with the
Autor:
Ana M.P. Melo, Marta C. Justino, Tim W. Overton, Joana M. Baptista, Jeffrey A. Cole, Lígia M. Saraiva, Ying Li
Publikováno v:
Journal of Bacteriology. 190:2004-2013
Expression of two genes of unknown function, Staphylococcus aureus scdA and Neisseria gonorrhoeae dnrN , is induced by exposure to oxidative or nitrosative stress. We show that DnrN and ScdA are di-iron proteins that protect their hosts from damage c
Publikováno v:
Journal of Biological Chemistry. 280:2636-2643
Nitric oxide produced by activated macrophages plays a key role as one of the immune system's weapons against pathogens. Because the lifetime of nitric oxide is short in aerobic conditions, whereas in anaerobic conditions the cytotoxic effects of nit
Publikováno v:
Journal of Microbiological Methods. 81:77-79
We show that genomic hybridization allows detection of a spontaneous secondary deletion of 126 genes that occurred during construction of an Escherichia coli ytfE mutant, LMS4209, explaining some of its unexpected growth defects. We confirm that YtfE