Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Marta Bugaj"'
Autor:
Jolanta Janiszewska, Inmaculada Posadas, Pablo Játiva, Marta Bugaj-Zarebska, Zofia Urbanczyk-Lipkowska, Valentín Ceña
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0165704 (2016)
Glioblastomas are the most common malignant primary brain tumours in adults and one of the most aggressive and difficult-to-treat cancers. No effective treatment exits actually for this tumour and new therapeutic approaches are needed for this diseas
Externí odkaz:
https://doaj.org/article/2a929ae6d22c47168c68b64652b58afa
Publikováno v:
Journal of Molecular Structure. 1284:135402
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a775e0883fe8b847b80729f0adf9d6a
https://doi.org/10.1016/j.molstruc.2023.135402
https://doi.org/10.1016/j.molstruc.2023.135402
Autor:
Charles-Henry Fabritius, Paulina Węgrzyn, Agata Stasiowska, Marta Bugaj, Andrzej Mazan, Monika Dobrzańska, Karolina Gluza, Piotr Kowalczyk, Ewa Kolasińska, Adrian Zarebski, Przemyslaw Zawadzki, Karolina Krawczynska, Aneta Bobowska, Anna Cierpich, Małgorzata Żurawska, Nicolas Boutard, Mariusz Milik, Katarzyna Wiklik, Anna Buda, Małgorzata Jarosz, Krzysztof Brzózka, Aleksandra Sabiniarz, Mariusz Galek, Edyta Palacz, Klaudia Czerwińska, Claude Commandeur
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 29:607-613
Maternal embryonic leucine zipper kinase (MELK) is involved in several key cellular processes and displays increased levels of expression in numerous cancer classes (colon, breast, brain, ovary, prostate and lung). Although no selective MELK inhibito
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0811d2cb5e37f7797b44a0953a2ff63
https://doi.org/10.1016/j.bmcl.2018.12.051
https://doi.org/10.1016/j.bmcl.2018.12.051
Autor:
Krzysztof Brzózka, Alan P. Watt, Michal Galezowski, Magdalena Mroczkowska, Stefan Chmielewski, Grzegorz Witold Topolnicki, Christopher A. Gabel, David J. Schultz, John R. Doedens, Charles-Henry Fabritius, Oleksandr Levenets, Piotr Kowalczyk, Piotr Urbanski, Katarzyna Palica, Nicolas Boutard, Anna Cierpich, Roderick A. Porter, Marta Bugaj, Jakub Woyciechowski, Marta Sowinska, David G. Harrison
Publikováno v:
Bioorganicmedicinal chemistry letters. 30(23)
The NLRP3 inflammasome is a component of the innate immune system involved in the production of proinflammatory cytokines. Aberrant activation by a wide range of exogenous and endogenous signals can lead to chronic, low-grade inflammation. It has att
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b9b9567b37c2ffb77ffeec192329547
https://pubmed.ncbi.nlm.nih.gov/32956781
https://pubmed.ncbi.nlm.nih.gov/32956781
Publikováno v:
Chemistry-An Asian Journal
Chemistry-An Asian Journal, Wiley-VCH Verlag, 2020, 15 (8), pp.1369-1375. ⟨10.1002/asia.202000129⟩
Chemistry-An Asian Journal, Wiley-VCH Verlag, 2020, 15 (8), pp.1369-1375. ⟨10.1002/asia.202000129⟩
International audience; A new methodology for the double N-arylation of diketopyrrolopyrroles with aryl triflates has been developed. It is now possible to prepare diketopyrrolopyrroles bearing N-substituents derived from naphthalene, anthracene and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8de52b1146667b9b15a4cc640145dabc
https://hal.archives-ouvertes.fr/hal-03426255
https://hal.archives-ouvertes.fr/hal-03426255
Autor:
Bożena Winnik, Ewelina Wincza, Krzysztof Brzózka, Ewa Jabłońska, Grzegorz Dubin, Krzysztof Warzocha, Tomasz Sewastianik, Małgorzata Żurawska, Pawel Guzik, Wojciech Czardybon, Izabela Dolata, Ewa Kolasińska, Aleksandra Sabiniarz, Ewa Lech-Marańda, Anna Szumera-Ciećkiewicz, Marta Bugaj, Monika Prochorec-Sobieszek, Elżbieta Mądro, Aniela Golas, Monika Noyszewska-Kania, Ewelina Gabor-Worwa, Renata Windak, Eliza Majewska, Maciej Szydlowski, Magdalena Salwińska, Monika Danielewicz, Bartosz Pula, Milena Mazan, Magdalena Zawadzka, Przemyslaw Juszczynski, Michal Galezowski, Jerome Tamburini
Publikováno v:
Oncotarget
Fms-like tyrosine kinase 3 internal tandem duplication (FLT3-ITD) is one of the most common genetic lesions in acute myeloid leukemia patients (AML). Although FLT3 tyrosine kinase inhibitors initially exhibit clinical activity, resistance to treatmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::571ff8c752af14837f1e6bb39878735f
https://doi.org/10.18632/oncotarget.24747
https://doi.org/10.18632/oncotarget.24747
Autor:
Kinga Michalik, Peter Littlewood, Karolina Gluza, Katarzyna Banaszak, Agata Dudek, Agnieszka Piatek, Marta Bugaj, Sujit Sasmal, Adam Radzimierski, Michal Galezowski, Eliza Zimolag, Pawel Guzik, Magdalena Zastawna, Marta Sowinska, Krzysztof Brzózka, Joanna Szeremeta-Spisak, Stefan Chielewski, Oleksandr Levenets, Przemysław Wyrębek, Anna Zagorska, Adrian Podkowa, Aniela Golas, Iana Levenets, Maciej Kujawa, Martin Swarbrick, Stefan Chmielewski, Patryk Kret, Andrzej Gondela, Mateusz Swirski, Sylwia Sudoł, Dominika Stanko, Agnieszka Gibas, Marianna Girardi, Karol Zuchowicz, Mateusz Ogórek, Marcin Nowogrodzki, Paulina Niedziejko
Publikováno v:
Journal for ImmunoTherapy of Cancer. 9:A786-A786
BackgroundHematopoietic progenitor kinase 1 (HPK1, MAP4K1) is emerging as a well-renowned, druggable target for T cell-based immunotherapies. HPK1 is a member of the serine/threonine MAP4K family, predominantly expressed in hematopoietic cell lineage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5821838afc896b6719c38225bf063f9f
https://doi.org/10.1136/jitc-2021-sitc2021.752
https://doi.org/10.1136/jitc-2021-sitc2021.752
Autor:
Kinga Michalik, Karol Zuchowicz, Karolina Gluza, Anna Bartosik, Magdalena Zastawna, Wojciech Jasnosz, Nicolas Boutard, Andrzej Gondela, Eliza Zimoląg, Patryk Kret, Marta Bugaj, Aneta Bobowska, Sylwia Sudoł, Pawel Guzik, Maciej Kujawa, Peter Littlewood, Aleksandra Więckowska, Sujit Sasmal, David Synak, Katarzyna Banaszak, Przemysław Wyrębek, Joanna Szeremeta-Spisak, Wojciech Schonemann, Agnieszka Gibas, Mateusz Świrski, Marianna Girardi, Monika Dobrzańska, Michal Galezowski, Kostiantyn Krolenko, Marcin Nowogrodzki, Agata Dudek, Urszula Kulesza, Mateusz Ogórek, Krzysztof Brzózka, Katarzyna Wnuk-Lipinska, Oleksandr Leventes, Adrian Podkowa, Stefan Chmielewski
Publikováno v:
Cancer Research. 81:1281-1281
Background: Hematopoietic progenitor kinase 1 (HPK1, MAP4K1) is a member of the serine/threonine MAP4K family predominantly expressed in hematopoietic cell lineages which plays a pivotal role in the negative regulation of the signaling cascade trigge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d5e702c70b2fb184d24629734608dc8
https://doi.org/10.1158/1538-7445.am2021-1281
https://doi.org/10.1158/1538-7445.am2021-1281
Autor:
Peter Littlewood, Katarzyna Banaszak, Sylwia Sudoł, Jakub Pięta, Marcin Walczak, Anita Janiga, Karolina Gluza, Eliza Zimoląg, Przemysław Wyrębek, Kinga Michalik, Adrian Podkowa, Luigi Stasi, Katarzyna Maciejewska, Anna Bartosik, Roberta Bartolotta, Maciej Kujawa, Aniela Golas, Pawel Guzik, Ewelina Rutkowska, Stefan Chmielewski, Krzysztof Brzózka, Grzegorz Wilkowski, Marta Bugaj, Katarzyna Wnuk-Lipinska, Aleksandra Brzdonkiewicz, Wojciech Jasnosz, Grzegorz Witold Topolnicki, Patryk Kret, Charles Fabritius, Agata Dudek, Adam Radzimierski, Marcin Nowogrodzki, Monika Dobrzańska, Kostiantyn Krolenko, Tushar Mahajan, Agnieszka Gibas
Publikováno v:
Cancer Research. 80:1947-1947
Background: Hematopoietic progenitor kinase 1 (HPK1, MAP4K1) is predominantly expressed in hematopoietic cell linages and serves as a negative regulator of T cells and dendritic cells (DC). Alteration of ERK/MAPK pathway by HPK1 in T-cells and dendri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::07cab42f33aeb1a4b66aeb8c66956487
https://doi.org/10.1158/1538-7445.am2020-1947
https://doi.org/10.1158/1538-7445.am2020-1947
Autor:
Marta Bugaj-Zarebska, Valentín Ceña, Zofia Urbańczyk-Lipkowska, Jolanta Janiszewska, Pablo Játiva, Inmaculada Posadas
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0165704 (2016)
PLoS ONE
PLoS ONE
Glioblastomas are the most common malignant primary brain tumours in adults and one of the most aggressive and difficult-to-treat cancers. No effective treatment exits actually for this tumour and new therapeutic approaches are needed for this diseas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd8fc84c7e15d3b26e97beaa5dbc7a0d
http://europepmc.org/articles/PMC5104433?pdf=render
http://europepmc.org/articles/PMC5104433?pdf=render