Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Marta Borchiellini"'
Publikováno v:
Particles, Vol 7, Iss 2, Pp 417-434 (2024)
Isotopic composition measurements of singly charged cosmic rays (CR) provide essential insights into CR transport in the Galaxy. The Alpha Magnetic Spectrometer (AMS-02) can identify singly charged isotopes up to about 10 GeV/n. However, their identi
Externí odkaz:
https://doaj.org/article/b22ae674f9f64879976e47838c87d406
Autor:
Carla L. Esposito, Ida Autiero, Annamaria Sandomenico, H. Li, Mahmoud A. Bassal, Maria L. Ibba, Dongfang Wang, Lucrezia Rinaldi, Simone Ummarino, Giulia Gaggi, Marta Borchiellini, Piotr Swiderski, Menotti Ruvo, Silvia Catuogno, Alexander K. Ebralidze, Marcin Kortylewski, Vittorio de Franciscis, Annalisa Di Ruscio
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Here the authors generate an RNA-based platform to neutralize the major epigenetic player DNMT1. Using this targeted approach, aberrant DNA methylation in cancer can be corrected.
Externí odkaz:
https://doaj.org/article/1ac7b00822ad42efaffe5d498c64c726
Autor:
Simone Ummarino, Clinton Hausman, Giulia Gaggi, Lucrezia Rinaldi, Mahmoud A. Bassal, Yanzhou Zhang, Andy Joe Seelam, Ikei S. Kobayashi, Marta Borchiellini, Alexander K. Ebralidze, Barbara Ghinassi, Bon Q. Trinh, Susumu S. Kobayashi, Annalisa Di Ruscio
Publikováno v:
Cells, Vol 10, Iss 11, p 2986 (2021)
Nutritional intake impacts the human epigenome by directing epigenetic pathways in normal cell development via as yet unknown molecular mechanisms. Consequently, imbalance in the nutritional intake is able to dysregulate the epigenetic profile and dr
Externí odkaz:
https://doaj.org/article/95f6f216f4354e839427510a4d5e52e5
Publikováno v:
Cells, Vol 8, Iss 10, p 1243 (2019)
DNA methylation controls several cellular processes, from early development to old age, including biological responses to endogenous or exogenous stimuli contributing to disease transition. As a result, minimal DNA methylation changes during developm
Externí odkaz:
https://doaj.org/article/4f863f2f6d7e42b49b8441cdcc53acef
Autor:
Hajime Karasuyama, Nouraiz Ahmed, Kensuke Miyake, Francisco Marchi, Shin-Young Park, Haoran Zhang, Anuya Paranjape, Marta Borchiellini, Stephen J. Galli, Sisi Chen, Junyan Zhang, Daniel G. Tenen, Elaine Dzierzak, Annalisa Di Ruscio, Sweta B. Patel, Samanta A. Mariani, Timm Schroeder, Mindy Tsai, Mahmoud A. Bassal, Robert S. Welner, Anais Wanet
Publikováno v:
Science Immunology, 6 (56)
E-cadherin is a calcium-dependent cell-cell adhesion molecule extensively studied for its involvement in tissue formation, epithelial cell behavior, and suppression of cancer. However, E-cadherin expression in the hematopoietic system has not been fu
Autor:
Carla L. Esposito, Ida Autiero, Annamaria Sandomenico, H. Li, Mahmoud A. Bassal, Maria L. Ibba, Dongfang Wang, Lucrezia Rinaldi, Simone Ummarino, Giulia Gaggi, Marta Borchiellini, Piotr Swiderski, Menotti Ruvo, Silvia Catuogno, Alexander K. Ebralidze, Marcin Kortylewski, Vittorio de Franciscis, Annalisa Di Ruscio
Publikováno v:
Nature communications. 14(1)
DNA methylation is a fundamental epigenetic modification regulating gene expression. Aberrant DNA methylation is the most common molecular lesion in cancer cells. However, medical intervention has been limited to the use of broadly acting, small mole
Autor:
Susumu Kobayashi, Yanzhou Zhang, Marta Borchiellini, Simone Ummarino, Alexander K. Ebralidze, Annalisa Di Ruscio, Mahmoud A. Bassal, Andy Joe Seelam, Ikei S. Kobayashi, Bon Q. Trinh
Nutritional intake impacts the human epigenome by directing epigenetic pathways in normal cell development via as yet unknown molecular mechanisms. Consequently, imbalance in the nutritional intake is able to dysregulate the epigenetic profile and dr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::97abfaa05ad9efcf0fa067b052eadd45
https://doi.org/10.1101/2020.07.31.231555
https://doi.org/10.1101/2020.07.31.231555
Autor:
Carla Lucia Esposito, MA Basal, Marta Borchiellini, Silvia Catuogno, Annamaria Sandomenico, A Di Ruscio, Simone Ummarino, V de Franciscis, Alexander K. Ebralidze, Ida Autiero, Menotti Ruvo
DNA methylation is a fundamental epigenetic modification regulating gene expression. Aberrant DNA methylation is the most common molecular lesion in cancer cells. However, medical intervention has been limited to the use of toxic, unspecific demethyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bd699b5833e755b07188238618ba41d6
https://doi.org/10.1101/2020.07.29.226803
https://doi.org/10.1101/2020.07.29.226803
Autor:
Barbara Ghinassi, Andy Joe Seelam, Yanzhou Zhang, Lucrezia Rinaldi, Susumu Kobayashi, Marta Borchiellini, Giulia Gaggi, Clinton Hausman, Annalisa Di Ruscio, Alexander K. Ebralidze, Simone Ummarino, Bon Q. Trinh, Ikei S. Kobayashi, Mahmoud A. Bassal
Publikováno v:
Cells
Volume 10
Issue 11
Cells, Vol 10, Iss 2986, p 2986 (2021)
Volume 10
Issue 11
Cells, Vol 10, Iss 2986, p 2986 (2021)
Nutritional intake impacts the human epigenome by directing epigenetic pathways in normal cell development via as yet unknown molecular mechanisms. Consequently, imbalance in the nutritional intake is able to dysregulate the epigenetic profile and dr
Autor:
Carla Lucia Esposito, Marta Borchiellini, Simone Ummarino, Silvia Catuogno, Mahmoud A. Bassal, Ida Autiero, Menotti Ruvo, Annalisa Di Ruscio, Vittorio de Franciscis, Alexander K. Ebralidze, Sandomenico Annamaria
Publikováno v:
Blood. 136:3-4
DNA methylation is a major signature involved in the regulation of gene expression. Numerous studies have established a link between aberrant DNA methylation and cancer (Herman and Baylin 2003, Baylin and Jones 2011, Feinberg 2018). Myelodysplastic s