Peripheral inflammatory immune response differs among sporadic and familial Parkinson’s disease

Autor: Laura Muñoz-Delgado, Daniel Macías-García, María Teresa Periñán, Silvia Jesús, Astrid D. Adarmes-Gómez, Marta Bonilla Toribio, Dolores Buiza Rueda, María del Valle Jiménez-Jaraba, Belén Benítez Zamora, Rafael Díaz Belloso, Sergio García-Díaz, Miguel Martín-Bórnez, Rocío Pineda Sánchez, Fátima Carrillo, Pilar Gómez-Garre, Pablo Mir

Publikováno v: npj Parkinson's Disease, Vol 9, Iss 1, Pp 1-9 (2023)

Abstract Peripheral inflammatory immune responses are thought to play a major role in the pathogenesis of Parkinson’s disease (PD). The neutrophil-to-lymphocyte ratio (NLR), a biomarker of systemic inflammation, has been reported to be higher in pa

Externí odkaz: https://doaj.org/article/52eba1144fa34462b2f4bc237ba2e7c9

TMEM230 in Parkinson's disease in a southern Spanish population.

Autor: Cristina Tejera-Parrado, Silvia Jesús, Adrián López-Ruíz, Dolores Buiza-Rueda, Marta Bonilla-Toribio, Inmaculada Bernal-Bernal, María Teresa Periñán, Laura Vargas-González, Pilar Gómez-Garre, Pablo Mir

Publikováno v: PLoS ONE, Vol 13, Iss 5, p e0197271 (2018)

TMEM230 has been associated with autosomal dominant Parkinson's disease (PD). Subsequent studies have remained negative, and none of previous described mutation has been reported anymore. We investigated the implication of this gene in the PD in a po

Externí odkaz: https://doaj.org/article/3bbdfdc4d64c464f898ee6902098dd74

Homocysteine levels, genetic background, and cognitive impairment in Parkinson's disease

Autor: María Teresa, Periñán, Daniel, Macías-García, Silvia, Jesús, Juan Francisco, Martín-Rodríguez, Laura, Muñoz-Delgado, Maria Valle, Jimenez-Jaraba, Dolores, Buiza-Rueda, Marta, Bonilla-Toribio, Astrid Daniela, Adarmes-Gómez, Pilar, Gómez-Garre, Pablo, Mir

Publikováno v: Journal of neurology.

Hyperhomocysteinemia is considered an independent risk factor for cognitive impairment.To study the correlation between homocysteine levels and cognitive impairment in patients with PD.We conducted a case-control study that included 246 patients with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::08c228e8a24cefd7c65aaf096a888299
https://pubmed.ncbi.nlm.nih.gov/36169739

Reply to: 'Increased Stroke Risk in Patients with Parkinson's Disease with LRRK2 Mutations'

Autor: Daniel Macías‐García, María Teresa Periñán, Laura Muñoz‐Delgado, Silvia Jesús, María Valle Jimenez‐Jaraba, Dolores Buiza‐Rueda, Marta Bonilla‐Toribio, Astrid Adarmes‐Gómez, Fátima Carrillo, Pilar Gómez‐Garre, Pablo Mir

Publikováno v: Movement disorders : official journal of the Movement Disorder SocietyReferences. 37(5)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::596848da62fe5408a7dc4cc7a39349bb
https://pubmed.ncbi.nlm.nih.gov/35587629

A geroscience approach for Parkinson's disease: Conceptual framework and design of PROPAG-AGEING project

Autor: Chiara Pirazzini, Tiago Azevedo, Luca Baldelli, Anna Bartoletti-Stella, Giovanna Calandra-Buonaura, Alessandra Dal Molin, Giovanna Maria Dimitri, Ivan Doykov, Pilar Gómez-Garre, Sara Hägg, Jenny Hällqvist, Claire Halsband, Wendy Heywood, Silvia Jesús, Juulia Jylhävä, Katarzyna Malgorzata Kwiatkowska, Miguel A. Labrador-Espinosa, Cristina Licari, Maria Giovanna Maturo, Giacomo Mengozzi, Gaia Meoni, Maddalena Milazzo, Maria Teresa Periñán-Tocino, Francesco Ravaioli, Claudia Sala, Luisa Sambati, Sebastian Schade, Sebastian Schreglmann, Simeon Spasov, Leonardo Tenori, Dylan Williams, Luciano Xumerle, Elisa Zago, Kailash P. Bhatia, Sabina Capellari, Pietro Cortelli, Paolo Garagnani, Henry Houlden, Pietro Liò, Claudio Luchinat, Massimo Delledonne, Kevin Mills, Pablo Mir, Brit Mollenhauer, Christine Nardini, Nancy L. Pedersen, Federica Provini, Stephen Strom, Claudia Trenkwalder, Paola Turano, Maria Giulia Bacalini, Claudio Franceschi, Astrid Adarmes-Gómez, Marta Bonilla-Toribio, Claudia Boninsegna, Marcella Broli, Dolores Buiza-Rueda, Mario Carrión-Claro, Rosalia Cilea, Robert Clayton, Silvia De Luca, Patrizia De Massis, Rocio Escuela-Martin, Giovanni Fabbri, Anna Gabellini, Cristina Giuliani, Pietro Guaraldi, Ismae Huertas, Daniel Macias, Stefania Macrì, Francesca Magrinelli, Juan Francisco Martín Rodríguez, Francesco Mignani, Stefania Alessandra Nassetti, Cesa Lorella Maria Scaglione, Cristina Tejera-Parrado, Franco Valzania, Rosario Vigo Ortega

Publikováno v: Mechanisms of ageing and development
194 (2021). doi:10.1016/j.mad.2020.111426
info:cnr-pdr/source/autori:Pirazzini, Chiara; Azevedo, Tiago; Baldelli, Luca; Bartoletti-Stella, Anna; Calandra-Buonaura, Giovanna; Dal Molin, Alessandra; Dimitri, Giovanna Maria; Doykov, Ivan; Gómez-Garre, Pilar; Hägg, Sara; Hällqvist, Jenny; Halsband, Claire; Heywood, Wendy; Jesús, Silvia; Jylhävä, Juulia; Kwiatkowska, Katarzyna Malgorzata; Labrador-Espinosa, Miguel A.; Licari, Cristina; Maturo, Maria Giovanna; Mengozzi, Giacomo; Meoni, Gaia; Milazzo, Maddalena; Periñán-Tocino, Maria Teresa; Ravaioli, Francesco; Sala, Claudia; Sambati, Luisa; Schade, Sebastian; Schreglmann, Sebastian; Spasov, Simeon; Tenori, Leonardo; Williams, Dylan; Xumerle, Luciano; Zago, Elisa; Bhatia, Kailash P.; Capellari, Sabina; Cortelli, Pietro; Garagnani, Paolo; Houlden, Henry; Liò, Pietro; Luchinat, Claudio; Delledonne, Massimo; Mills, Kevin; Mir, Pablo; Mollenhauer, Brit; Nardini, Christine; Pedersen, Nancy L.; Provini, Federica; Strom, Stephen; Trenkwalder, Claudia; Turano, Paola; Bacalini, Maria Giulia; Franceschi, Claudio; Adarmes-Gómez, Astrid; Bonilla-Toribio, Marta; Boninsegna, Claudia; Broli, Marcella; Buiza-Rueda, Dolores; Carrión-Claro, Mario; Cilea, Rosalia; Clayton, Robert; Molin, Alessandra Dal; De Luca, Silvia; De Massis, Patrizia; Escuela-Martin, Rocio; Fabbri, Giovanni; Gabellini, Anna; Giuliani, Cristina; Guaraldi, Pietro; Huertas, Ismae; Macias, Daniel; Macrì, Stefania; Magrinelli, Francesca; Rodríguez, Juan Francisco Martín; Mignani, Francesco; Nassetti, Stefania Alessandra; Scaglione, Cesa Lorella Maria; Tejera-Parrado, Cristina; Valzania, Franco; Ortega, Rosario Vigo/titolo:A geroscience approach for Parkinson's disease: Conceptual framework and design of PROPAG-AGEING project/doi:10.1016%2Fj.mad.2020.111426/rivista:Mechanisms of ageing and development (Print)/anno:2021/pagina_da:/pagina_a:/intervallo_pagine:/volume:194

Advanced age is the major risk factor for idiopathic Parkinson's disease (PD), but to date the biological relationship between PD and ageing remains elusive. Here we describe the rationale and the design of the H2020 funded project "PROPAG-AGEING", w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab42111826f022ce26b166f667a14efe
https://pubmed.ncbi.nlm.nih.gov/33385396