Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Marta Bombardo"'
Autor:
Andrew P. Hills, Stephen Myers, Sabrina Sonda, Domenico Salvatore, Rolf Graf, Monica Dentice, Theresia Reding, Ermanno Malagola, Rong Chen, Enrica Saponara, Marta Bombardo
Publikováno v:
The Journal of Pathology. 248:217-229
Proliferation of pancreatic acinar cells is a critical process in the pathophysiology of pancreatic diseases, because limited or defective proliferation is associated with organ dysfunction and patient morbidity. In this context, elucidating the sign
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::062f61f1da6eeddadabadc1ba023a276
https://doi.org/10.1002/path.5247
https://doi.org/10.1002/path.5247
Autor:
Gitta Maria Seleznik, Rossella Parrotta, Sabrina Sonda, Paola Martinelli, Amedeo Caflisch, Francesco Baschieri, Rolf Graf, Irene Esposito, Michele Visentin, Marta Bombardo, Ermanno Malagola, Johanna Buschmann, Hesso Farhan, Rong Chen, Nathalie Borgeaud, Enrica Saponara
Publikováno v:
The Journal of Pathology. 246:352-365
Pancreatic ductal adenocarcinoma (PDAC), the primary cause of pancreatic cancer mortality, is poorly responsive to currently available interventions. Identifying new targets that drive PDAC formation and progression is critical to develop alternative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e17b0940939d0363e46511478fac94f6
https://doi.org/10.1002/path.5147
https://doi.org/10.1002/path.5147
Autor:
Rolf Graf, Ermanno Malagola, Andrew P. Hills, Marta Bombardo, Rong Chen, Sabrina Sonda, Enrica Saponara
Publikováno v:
Molecular Pharmacology. 94:793-801
Pancreatic fibrosis is the hallmark of chronic pancreatitis, a highly debilitating disease for which there is currently no cure. The key event at the basis of pancreatic fibrosis is the deposition of extracellular matrix proteins by activated pancrea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a850d1d4451fb7f485462874c0f7240b
https://doi.org/10.1124/mol.117.110924
https://doi.org/10.1124/mol.117.110924
Autor:
Enrica Saponara, Theresia Reding, Evans Quilichini, Anja Zabel, Rong Chen, Cécile Haumaitre, Gitta Maria Seleznik, Marta Bombardo, Ermanno Malagola, Rolf Graf, Sabrina Sonda
Publikováno v:
British Journal of Pharmacology. 174:3865-3880
Background and Purpose Pancreatitis is a common inflammation of the pancreas with rising incidence in many countries. Despite improvements in diagnostic techniques, the disease is associated with high risk of severe morbidity and mortality and there
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c77c22bc756960e1ded6cd72ecefabd
https://doi.org/10.1111/bph.13984
https://doi.org/10.1111/bph.13984
Publikováno v:
British Journal of Pharmacology. 175:335-347
Background and Purpose Nonsteroidal anti-inflammatory drugs (NSAIDs) are administered to manage pain typically found in patients suffering from pancreatitis. NSAIDs also display anti-proliferative activity against cancer cells, however their effects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e2c71b6caa8e2e68beeb3989f996db1a
https://doi.org/10.1111/bph.13867
https://doi.org/10.1111/bph.13867
Autor:
Rong Chen, Sabrina Sonda, Ermanno Malagola, Rolf Graf, Gitta Maria Seleznik, Marta Bombardo, Andrew P. Hills, Arcangelo F. Carta
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Scientific Reports
Scientific Reports
Adult pancreatic acinar cells have the ability to re-enter the cell cycle and proliferate upon injury or tissue loss. Despite this mitotic ability, the extent of acinar proliferation is often limited and unable to completely regenerate the injured ti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a81e2188f9789bf2febe38b52b8ea99a
https://doi.org/10.5167/uzh-166051
https://doi.org/10.5167/uzh-166051
Autor:
Enrica, Saponara, Michele, Visentin, Francesco, Baschieri, Gitta, Seleznik, Paola, Martinelli, Irene, Esposito, Johanna, Buschmann, Rong, Chen, Rossella, Parrotta, Nathalie, Borgeaud, Marta, Bombardo, Ermanno, Malagola, Amedeo, Caflisch, Hesso, Farhan, Rolf, Graf, Sabrina, Sonda
Publikováno v:
The Journal of pathology. 246(3)
Pancreatic ductal adenocarcinoma (PDAC), which is the primary cause of pancreatic cancer mortality, is poorly responsive to currently available interventions. Identifying new targets that drive PDAC formation and progression is critical for developin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::547c856e3ab0a7eba52fd5228bc1c4b1
https://pubmed.ncbi.nlm.nih.gov/30058725
https://pubmed.ncbi.nlm.nih.gov/30058725
Autor:
Anja Zabel, Rolf Graf, Marta Bombardo, Enrica Saponara, Kamile Grabliauskaite, Theresia Reding, Carmen Faso, Gitta Maria Seleznik, Ermanno Malagola, Sabrina Sonda
Publikováno v:
The Journal of Pathology. 238:434-445
Determining signalling pathways that regulate pancreatic regeneration following pancreatitis is critical for implementing therapeutic interventions. In this study we elucidated the molecular mechanisms underlying the effects of transforming growth fa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::112d72c24aedb06869f33bd7e09ba42c
https://doi.org/10.1002/path.4666
https://doi.org/10.1002/path.4666
Autor:
Adrian B. Hehl, Kamile Grabliauskaite, Theresia Reding, Rolf Graf, Enrica Saponara, Yinghua Tian, Alberto B. Silva, Elisabeth M. Schraner, Sabrina Sonda, Ermanno Malagola, Gitta Maria Seleznik, Raphael M Buzzi, Marta Bombardo, Anja Zabel
Publikováno v:
The Journal of Pathology. 237:495-507
The exocrine pancreas exhibits a distinctive capacity for tissue regeneration and renewal following injury. This regenerative ability has important implications for a variety of disorders, including pancreatitis and pancreatic cancer, diseases associ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::952e26b9f9b0372e0228248534723678
https://doi.org/10.1002/path.4595
https://doi.org/10.1002/path.4595
Autor:
Marta, Bombardo, Rong, Chen, Ermanno, Malagola, Enrica, Saponara, Andrew P, Hills, Rolf, Graf, Sabrina, Sonda
Publikováno v:
Molecular pharmacology. 94(2)
Pancreatic fibrosis is the hallmark of chronic pancreatitis, a highly debilitating disease for which there is currently no cure. The key event at the basis of pancreatic fibrosis is the deposition of extracellular matrix proteins by activated pancrea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c560186e1acc2b21e60210b92e8872a9
https://pubmed.ncbi.nlm.nih.gov/29880639
https://pubmed.ncbi.nlm.nih.gov/29880639