Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Marta B. Mazzetti"'
Publikováno v:
Toxicology Reports, Vol 3, Iss , Pp 141-147 (2016)
This work investigated the modulation by melatonin (Mel) of the effects of the porphyrinogenic drugs 2-allyl-2-isopropylacetamide (AIA) and 3,5-diethoxycarbonyl-1,4-dihydro-2,4,6-collidine (DDC) on oxidative environment, glucose biosynthesis and heme
Externí odkaz:
https://doaj.org/article/43a33ee0d6564b1cafee973191d59fc4
Publikováno v:
Toxicology Reports, Vol 3, Iss, Pp 141-147 (2016)
Toxicology Reports
Toxicology Reports
Highlights • Melatonin partially eliminates the AIA/DDC-induced decrease in the activity of the gluconeogenic enzymes PEPCK and G6Pase. • Melatonin favors a glucose-mediated down-regulating effect on AIA/DDC-induced ALA-S. • Melatonin reduces A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1a6d08132dc6c68a0e2c7a79ddb68c1
http://www.sciencedirect.com/science/article/pii/S2214750015300998
http://www.sciencedirect.com/science/article/pii/S2214750015300998
Publikováno v:
Journal of Physiology and Biochemistry. 65:329-337
11 beta-hydroxysteroid dehydrogenase (HSDs) enzymes regulate the activity of glucocorticoids in target organs. HSD1, one of the two existing isoforms, locates mainly in CNS, liver and adipose tissue. HSD1 is involved in the pathogenesis of diseases s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bc2721e79cb5a3c8e15e8bd1035a702
https://doi.org/10.1007/bf03185927
https://doi.org/10.1007/bf03185927
Publikováno v:
Biochemical Pharmacology. 75:704-712
This study focuses on the alterations suffered by the serotoninergic and kinurenergic routes of tryptophan (TRP) metabolism in liver, and their relation with gluconeogenic phosphoenolpyruvate-carboxykinase (PEPCK) blockage in experimental acute porph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb9b7499d84bedd109d325dbfee834fd
https://doi.org/10.1016/j.bcp.2007.09.023
https://doi.org/10.1016/j.bcp.2007.09.023
Publikováno v:
Toxicology. 197:164-174
Hexachlorobenzene (HCB) is a fungicide of well-known porphyrinogenic ability, which induces an experimental porphyria that resembles human porphyria cutanea tarda (PCT) in several animal species. It has been demonstrated that high glucose ingestion p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a34715d5fc681c0c7f1e2e79abe8027e
https://doi.org/10.1016/j.tox.2003.12.014
https://doi.org/10.1016/j.tox.2003.12.014
Publikováno v:
Journal of Biochemical and Biophysical Methods. 45:75-86
Coproporphyrinogen oxidase, the sixth enzyme in the biosynthetic heme pathway, catalyzes the oxidative decarboxylation of coproporphyrinogen III to protoporphyrinogen IX. A reversed-phase high pressure liquid chromatography method was developed to me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7544a401dac9dc491a9ff38216605e5
https://doi.org/10.1016/s0165-022x(00)00101-9
https://doi.org/10.1016/s0165-022x(00)00101-9
Autor:
Marta B. Mazzetti, J. María Tomio
Publikováno v:
IUBMB Life. 42:685-692
Porphobilinogen deaminase was purified from human hepatocytes. A variety of group specific reagents have been used to achieve site-specific modifications to evaluate the potential role of such groups in the whole catalytic cycle. Treatment with dicar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c45ee9562975b08732f653c039bbf1b
https://doi.org/10.1080/15216549700203101
https://doi.org/10.1080/15216549700203101
Publikováno v:
Experimental biology and medicine (Maywood, N.J.). 238(2)
A classical acute porphyria model in rats consists of combined treatment with 2-allyl-2-isopropylacetamide (AIA) and 3,5-diethoxycarbonyl-1,4-dihydrocollidine (DDC). The present work describes the effects of this treatment on the pentose phosphate (P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::420bcb68936ba9323b112e28790ed063
https://pubmed.ncbi.nlm.nih.gov/23390166
https://pubmed.ncbi.nlm.nih.gov/23390166
Autor:
Daiana Fornes, Marta B. Mazzetti, Leonor C. San Martín de Viale, Florencia D’Andrea, Laura Matković
Publikováno v:
Toxicology. 290(1)
This work deals with the study of how porphyrinogenic drugs modeling acute porphyrias interfere with the status of carbohydrate-regulating hormones in relation to key glucose enzymes and to porphyria, considering that glucose modulates the developmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6eacecd4cd1cd4f230ca7707140e1277
https://pubmed.ncbi.nlm.nih.gov/21889565
https://pubmed.ncbi.nlm.nih.gov/21889565
Autor:
Elena B.C. Llambías, Marta B. Mazzetti, Leonor C. San Martín de Viale, Sandra M. Lelli, Carmen Aldonatti
Publikováno v:
International journal of toxicology. 26(6)
Hexachlorobenzene produces an experimental hepatic por-phyria in rats, which is similar to human porphyria cutanea tarda, with hyperpigmentation as one of its characteristic features. Alterations in tryptophan metabolism have been previously observed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a284d6f4ac8d59b1b29100c6dac4e13
https://pubmed.ncbi.nlm.nih.gov/18066970
https://pubmed.ncbi.nlm.nih.gov/18066970