Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Marta Abreu-Paiva"'
Autor:
Alessondra T. Speidel, Daniel J. Stuckey, Lesley W. Chow, Laurence H. Jackson, Michela Noseda, Marta Abreu Paiva, Michael D. Schneider, Molly M. Stevens
Publikováno v:
ACS Central Science, Vol 3, Iss 4, Pp 338-348 (2017)
Externí odkaz:
https://doaj.org/article/f2f478710f3d4e048a4614a319bc5f01
Autor:
Priyanka Narasimhan, Dörte Faust, Devika Sanmugalingam, Motoaki Sano, Lorna R. Fiedler, Caroline M. R. Low, Gary Newton, Michela Noseda, Michael D. Schneider, Weihua Song, Marta Abreu Paiva, Daniel J. Stuckey, Sam C. Wang, Rehan Aqil, Tse-Hua Tan, Trevor Perrior, Evie Maifoshie, Lorenzo Pavanello, Micaela Jenkins, George E. Taffet, Mark L. Entman, Sunthar Kanayaganam, Ashley Jarvis, Min Xie, Catherine Tralau-Stewart, Pelin Arabacilar Golforoush, Sian E. Harding, Lloyd H. Michael, Mohamed Bellahcene, Robert D. Sampson, Robert Yan, Mutsuo Harada, Kathryn Chapman, Josef Habib
Publikováno v:
Cell Stem Cell
Heart disease is a paramount cause of global death and disability. Although cardiomyocyte death plays a causal role and its suppression would be logical, no clinical counter-measures target the responsible intracellular pathways. Therapeutic progress
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df5ff2a02f8c189f051ad5f809c31c17
https://europepmc.org/articles/PMC6458995/
https://europepmc.org/articles/PMC6458995/
Autor:
Claire Morgan, Michael D. Schneider, Sian E. Harding, Peter O'Gara, Josef M. Penninger, Pascal Gellert, Leonardo Bottolo, Prashant K. Srivastava, Bonnie Razzaghi, Bernhard J. Haubner, Melissa J. Collins, Timothy J. Aitman, Marta Abreu Paiva, Martyna Adamowicz, Priyanka Raina, Laurence Game, Michela Noseda
Publikováno v:
Adamowicz-Brice, M, Morgan, C, Haubner, B J, Noseda, M, Collins, M J, Abreu Paiva, M, Srivastava, P K, Gellert, P, Razzaghi, B, O'Gara, P, Raina, P, Game, L, Bottolo, L, Schneider, M D, Harding, S E, Penninger, J & Aitman, T 2018, ' Functionally conserved non-coding regulators of cardiomyocyte proliferation and regeneration in mouse and human ', Circulation: Cardiovascular Genetics, vol. 11, no. 2 . https://doi.org/10.1161/CIRCGEN.117.001805
Background: The adult mammalian heart has little regenerative capacity after myocardial infarction (MI), whereas neonatal mouse heart regenerates without scarring or dysfunction. However, the underlying pathways are poorly defined. We sought to deriv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3650ddca0d327697dfaa772548a7204c
https://www.pure.ed.ac.uk/ws/files/53398381/Adamowicz_et_al_.pdf
https://www.pure.ed.ac.uk/ws/files/53398381/Adamowicz_et_al_.pdf
Autor:
Molly M. Stevens, Constant Morez, Marta Abreu Paiva, Michela Noseda, Elisa Belian, Michael D. Schneider
Publikováno v:
Biomaterials
Generation of de novo cardiomyocytes through viral over-expression of key transcription factors represents a highly promising strategy for cardiac muscle tissue regeneration. Although the feasibility of cell reprogramming has been proven possible bot
Autor:
Michela Noseda, Chrystalla Constantinou, Sara Samari, Patricia Chaves, Kevin Cheng, Chiara Beretta, Tiago Rito, Marta Abreu-Paiva, Ana Pombo, Michael D Schneider
Publikováno v:
Circulation Research. 121
The clinical progression of myocardial infarction, the foremost cause of death globally, to heart failure is proportionally higher with increasing infarct size. Thus, preventing cardiomyocyte loss at time of injury and stimulating self-repair are fru
Publikováno v:
Circulation journal : official journal of the Japanese Circulation Society. 79(7)
Over the past 2 decades, cardiac regeneration has evolved from an exotic fringe of cardiovascular biology to the forefront of molecular, genetic, epigenetic, translational, and clinical investigations. The unmet patient need is the paucity of self-re
Autor:
Mutsuo Harada, Sten Eirik W. Jacobsen, Sara J. McSweeney, Michela Noseda, R. Thomas Lumbers, Alexandra I. F. Blakemore, Iain C. Macaulay, Robert D. Sampson, Farah Al-Beidh, Mauricio Barahona, Pulivarthi H. Rao, Elisa Belian, Sian E. Harding, Thomas Leja, Adam J. de Smith, Josef Habib, Michael D. Schneider, Daniel J. Stuckey, Marta Abreu Paiva
Publikováno v:
Nature Communications
Cardiac progenitor/stem cells in adult hearts represent an attractive therapeutic target for heart regeneration, though (inter)-relationships among reported cells remain obscure. Using single-cell qRT–PCR and clonal analyses, here we define four su