In the quest for new targets for pathogen eradication: the adenylosuccinate synthetase from the bacterium Helicobacter pylori

Autor: Beata Wielgus-Kutrowska, Igor Stuparević, Marta Łyczek, Agnieszka Bzowska, Marija Luić, Natalia Mrnjavac, Ante Bubić, Ivana Leščić Ašler

Publikováno v: Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 33, Iss 1, Pp 1405-1414 (2018)
Journal of Enzyme Inhibition and Medicinal Chemistry

Adenylosuccinate synthetase (AdSS) is an enzyme at regulatory point of purine metabolism. In pathogenic organisms which utilise only the purine salvage pathway, AdSS asserts itself as a promising drug target. One of these organisms is Helicobacter py

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https://doaj.org/article/bf04bc0ee087458183a4240bb0f2d5af