Zobrazeno 1 - 10
of 145
pro vyhledávání: '"Marta, Rizzi"'
Autor:
Susanne Kessler, Bradly Burke, Geoffroy Andrieux, Jan Schinköthe, Lea Hamberger, Johannes Kacza, Shijun Zhan, Clara Reasoner, Taru S. Dutt, Maria Kaukab Osman, Marcela Henao-Tamayo, Julian Staniek, Jose Francisco Villena Ossa, Dalit T. Frank, Wenjun Ma, Reiner Ulrich, Toni Cathomen, Melanie Boerries, Marta Rizzi, Martin Beer, Martin Schwemmle, Peter Reuther, Tony Schountz, Kevin Ciminski
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Jamaican fruit bats (Artibeus jamaicensis) naturally harbor a wide range of viruses of human relevance. These infections are typically mild in bats, suggesting unique features of their immune system. To better understand the immune response
Externí odkaz:
https://doaj.org/article/c051c263d7674a128f1b9588cd87ed8d
Autor:
Anna-Maria Schaffer, Gina Jasmin Fiala, Miriam Hils, Eriberto Natali, Lmar Babrak, Laurenz Alexander Herr, Mari Carmen Romero-Mulero, Nina Cabezas-Wallscheid, Marta Rizzi, Enkelejda Miho, Wolfgang WA Schamel, Susana Minguet
Publikováno v:
eLife, Vol 13 (2024)
The ratio between κ and λ light chain (LC)-expressing B cells varies considerably between species. We recently identified Kinase D-interacting substrate of 220 kDa (Kidins220) as an interaction partner of the BCR. In vivo ablation of Kidins220 in B
Externí odkaz:
https://doaj.org/article/8e54cb9af4bb444790bb90fb84a3a4d3
Autor:
Eva-Maria Jacobsen, Dorit Fabricius, Magdalena Class, Fernando Topfstedt, Raquel Lorenzetti, Iga Janowska, Franziska Schmidt, Julian Staniek, Maria Zernickel, Thomas Stamminger, Andrea N. Dietz, Angela Zellmer, Manuel Hecht, Peter Rauch, Carmen Blum, Carolin Ludwig, Bernd Jahrsdörfer, Hubert Schrezenmeier, Maximilian Heeg, Benjamin Mayer, Alina Seidel, Rüdiger Groß, Jan Münch, Frank Kirchhoff, Sebastian F. N. Bode, Gudrun Strauss, Hanna Renk, Roland Elling, Maximillian Stich, Reinhard E. Voll, Burkhard Tönshof, Axel R. Franz, Philipp Henneke, Klaus-Michael Debatin, Marta Rizzi, Ales Janda
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Severity of SARS-CoV-2 infection is different in adults and children which involves the immune response. Here using a parent and children cohort with 4 month and 12 month sampling times, the authors show enhanced levels and increased breadth of anti-
Externí odkaz:
https://doaj.org/article/81ce609da88b45238e8d4a923e4304a2
Autor:
Eva-Maria Cox, Mohamed El-Behi, Stefanie Ries, Johannes F. Vogt, Vivien Kohlhaas, Thomas Michna, Benoît Manfroi, Mona Al-Maarri, Florian Wanke, Boaz Tirosh, Corinne Pondarre, Harry Lezeau, Nir Yogev, Romy Mittenzwei, Marc Descatoire, Sandra Weller, Jean-Claude Weill, Claude-Agnès Reynaud, Pierre Boudinot, Luc Jouneau, Stefan Tenzer, Ute Distler, Anne Rensing-Ehl, Christoph König, Julian Staniek, Marta Rizzi, Aude Magérus, Frederic Rieux-Laucat, F. Thomas Wunderlich, Nadine Hövelmeyer, Simon Fillatreau
Publikováno v:
Cell Reports, Vol 42, Iss 4, Pp 112378- (2023)
Summary: The signals controlling marginal zone (MZ) and follicular (FO) B cell development remain incompletely understood. Here, we show that AKT orchestrates MZ B cell formation in mice and humans. Genetic models that increase AKT signaling in B cel
Externí odkaz:
https://doaj.org/article/92cc14fd0e5540159395986a3869f5d7
Autor:
Victoria N. Cousin, Guillermo F. Perez, Kathryn J. Payne, Reinhard E. Voll, Marta Rizzi, Christopher G. Mueller, Klaus Warnatz
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Non-hematopoietic lymphoid stromal cells (LSC) maintain lymph node architecture and form niches allowing the migration, activation, and survival of immune cells. Depending on their localization in the lymph node, these cells display heterogeneous pro
Externí odkaz:
https://doaj.org/article/a6c59a15684240d5baec61c3f21568fe
Autor:
Xianyi Meng, Zhen Lin, Shan Cao, Iga Janowska, Koshiro Sonomoto, Darja Andreev, Knab Katharina, Jinming Wen, Karl Xaver Knaup, Michael Sean Wiesener, Gerhard Krönke, Marta Rizzi, Georg Schett, Aline Bozec
Publikováno v:
Bone Research, Vol 10, Iss 1, Pp 1-12 (2022)
Abstract In the bone marrow, B cells and bone-resorbing osteoclasts colocalize and form a specific microenvironment. How B cells functionally influence osteoclasts and bone architecture is poorly understood. Using genetically modified mice and high-t
Externí odkaz:
https://doaj.org/article/3dfcd33747ef418ba671e3b6b8d7e69e
Autor:
Hanna Renk, Alex Dulovic, Alina Seidel, Matthias Becker, Dorit Fabricius, Maria Zernickel, Daniel Junker, Rüdiger Groß, Janis Müller, Alexander Hilger, Sebastian F. N. Bode, Linus Fritsch, Pauline Frieh, Anneke Haddad, Tessa Görne, Jonathan Remppis, Tina Ganzemueller, Andrea Dietz, Daniela Huzly, Hartmut Hengel, Klaus Kaier, Susanne Weber, Eva-Maria Jacobsen, Philipp D. Kaiser, Bjoern Traenkle, Ulrich Rothbauer, Maximilian Stich, Burkhard Tönshoff, Georg F. Hoffmann, Barbara Müller, Carolin Ludwig, Bernd Jahrsdörfer, Hubert Schrezenmeier, Andreas Peter, Sebastian Hörber, Thomas Iftner, Jan Münch, Thomas Stamminger, Hans-Jürgen Groß, Martin Wolkewitz, Corinna Engel, Weimin Liu, Marta Rizzi, Beatrice H. Hahn, Philipp Henneke, Axel R. Franz, Klaus-Michael Debatin, Nicole Schneiderhan-Marra, Ales Janda, Roland Elling
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
In this prospective cohort study, authors follow 328 households in Germany with at least one confirmed SARS-CoV-2 infection and find that children are more likely to seroconvert without symptoms and have higher specific antibody levels that persist l
Externí odkaz:
https://doaj.org/article/af0bd9036d2c4e6cb0fbd39a1d97ce6a
Autor:
Natalie Frede, Raquel Lorenzetti, Janika M Hüppe, Iga Janowska, Arianna Troilo, Marei-Theresa Schleyer, Ana C. Venhoff, Reinhard E. Voll, Jens Thiel, Nils Venhoff, Marta Rizzi
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundJanus kinase (JAK) inhibitors have been approved for the treatment of several immune-mediated diseases (IMIDs) including rheumatoid arthritis (RA) and psoriatic arthritis and are in clinical trials for numerous other IMIDs. However, detaile
Externí odkaz:
https://doaj.org/article/e689dbc451254efba9b502d843ea7634
Autor:
Saskia Lehr, Felicitas Felber, Iliana Tantcheva-Poór, Christina Keßler, Rüdiger Eming, Alexander Nyström, Marta Rizzi, Dimitra Kiritsi
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Skin blistering disorders are associated with inherited defects in proteins involved in the dermal-epidermal adhesion or autoantibodies targeting those proteins. Although blistering in hereditary epidermolysis bullosa (EB) is pathogenetically linked
Externí odkaz:
https://doaj.org/article/1f1f66a65be04199980860036f12cf4e
Autor:
Anna-Lena Schäfer, Alexandra Eichhorst, Carolin Hentze, Antoine N. Kraemer, Anaïs Amend, Dalina T. L. Sprenger, Cara Fluhr, Stephanie Finzel, Christoph Daniel, Ulrich Salzer, Marta Rizzi, Reinhard E. Voll, Nina Chevalier
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Changed dietary habits in Western countries such as reduced fiber intake represent an important lifestyle factor contributing to the increase in inflammatory immune-mediated diseases. The mode of action of beneficial fiber effects is not fully elucid
Externí odkaz:
https://doaj.org/article/0f31083e9e75479e869b685ffd785408