Nongenetic Optical Modulation of Pluripotent Stem Cells Derived Cardiomyocytes Function in the Red Spectral Range

Autor: Carlotta Ronchi, Camilla Galli, Gabriele Tullii, Camilla Marzuoli, Marta Mazzola, Marco Malferrari, Silvia Crasto, Stefania Rapino, Elisa Di Pasquale, Maria Rosa Antognazza

Publikováno v: Advanced Science, Vol 11, Iss 3, Pp n/a-n/a (2024)

Abstract Optical stimulation in the red/near infrared range recently gained increasing interest, as a not‐invasive tool to control cardiac cell activity and repair in disease conditions. Translation of this approach to therapy is hampered by scarce

Externí odkaz: https://doaj.org/article/8bb4ec847c0f4a9d9700bc789c285ac0

Toward Cardiac Regeneration: Combination of Pluripotent Stem Cell-Based Therapies and Bioengineering Strategies

Autor: Marta Mazzola, Elisa Di Pasquale

Publikováno v: Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)

Cardiovascular diseases represent the major cause of morbidity and mortality worldwide. Multiple studies have been conducted so far in order to develop treatments able to prevent the progression of these pathologies. Despite progress made in the last

Externí odkaz: https://doaj.org/article/df0de8daabd84b9a8937b15382eaf344

Subchronic exposure to titanium dioxide nanoparticles modifies cardiac structure and performance in spontaneously hypertensive rats

Autor: Alessandra Rossini, Federico Quaini, Monia Savi, Stefano Rossi, Rossella Alinovi, Matteo Goldoni, Alessandra Pagliaro, Laura Gennaccaro, Donatella Stilli, Maricla Galetti, Caterina Frati, Marta Mazzola, Stéphane Lucas, Omar Lozano-Garcia, Antonio Mutti, Angela Falco, Michele Miragoli, Emilio Macchi, Viviana Meraviglia, Silvana Pinelli, Leonardo Bocchi

Publikováno v: Particle and Fibre Toxicology, Vol 16, Iss 1, Pp 1-18 (2019)
Particle and Fibre Toxicology
Rossi, S, Savi, M, Mazzola, M, Pinelli, S, Alinovi, R, Gennaccaro, L, Pagliaro, A, Meraviglia, V, Galetti, M, Lozano-Garcia, O, Rossini, A, Frati, C, Falco, A, Quaini, F, Bocchi, L, Stilli, D, Lucas, S, Goldoni, M, Macchi, E, Mutti, A & Miragoli, M 2019, ' Subchronic exposure to titanium dioxide nanoparticles modifies cardiac structure and performance in spontaneously hypertensive rats ', Particle and Fibre Toxicology, vol. 16, no. 1, 25, pp. 25 . https://doi.org/10.1186/s12989-019-0311-7

Background Non-communicable diseases, intended as the results of a combination of inherited, environmental and biological factors, kill 40 million people each year, equivalent to roughly 70% of all premature deaths globally. The possibility that manu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::385db94142b41acc6b5336509220a282
http://link.springer.com/article/10.1186/s12989-019-0311-7

Investigation of mechanisms of contractile dysfunctions due to LMNA mutations in a iPSC-based cardiac model of laminopathy

Autor: Gianluigi Condorelli, Paolo Kunderfranco, Matteo Dal Ferro, Nicolò Salvarani, Giuseppe Faggian, Michele Miragoli, Marta Mazzola, Carla Lucarelli, Silvia Crasto, Elisa Di Pasquale, Marianna Paulis

Publikováno v: Vascular Pharmacology. 132:106708

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4d804b22e7f641a1c3da5b96be9aca93
https://doi.org/10.1016/j.vph.2020.106708

Histone Methyltransferase G9a Is Required for Cardiomyocyte Homeostasis and Hypertrophy

Autor: Gianluigi Condorelli, Simone Serio, Michele Miragoli, Roberto Papait, Nicolò Salvarani, Marta Mazzola, Pierluigi Carullo, Francesca Rusconi, Christina Pagiatakis

Publikováno v: Circulation

Background: Correct gene expression programming of the cardiomyocyte underlies the normal functioning of the heart. Alterations to this can lead to the loss of cardiac homeostasis, triggering heart dysfunction. Although the role of some histone methy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f56c548d10358cf2ff1dc3fb65e0d577
https://pubmed.ncbi.nlm.nih.gov/28778944