Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Marta, Gielzak"'
Autor:
Jianfeng Xu, Jun Wei, Jennifer Beebe-Dimmer, Zhuqing Shi, Christopher Sample, Guifang Yan, Andrew Rifkin, Azita Sadeghpour, Marta Gielzak, Sodam Choi, David Moon, S. Lilly Zheng, Brian Helfand, Patrick Walsh, Kathleen Cooney, William Isaacs
Publikováno v:
The Prostate. 83:454-461
Background: Although men of African ancestry (AA) have the highest mortality rate from prostate cancer (PCa), relatively little is known about the germline variants that are associated with PCa risk in AA men. The goal of this study is to systematica
Autor:
Shuwei Li, Robert Hoiness, Siqun Lilly Zheng, Brian T. Helfand, Mary Helen Black, Jun Wei, Jefferey Chen, Jianfeng Xu, Kathleen E. Wiley, Stephanie Gutierrez, Brigette Tippin-Davis, Min-Tzu Lo, Hsiao Mei Lu, William B. Isaacs, Holly LaDuca, Zhuqing Shi, Marta Gielzak
Publikováno v:
The Prostate
Background Genome‐wide association studies have identified over 100 single‐nucleotide polymorphisms (SNPs) associated with prostate cancer (PrCa), and polygenic risk scores (PRS) based on their combined genotypes have been developed for risk stra
Autor:
Lilly S. Zheng, Christopher J. Sample, Daniel Rabizadeh, Jianfeng Xu, Jun Wei, Sodam Choi, Rong Na, William B. Isaacs, Marta Gielzak, Patrick C. Walsh, Kathleen A. Cooney
Publikováno v:
Br J Cancer
BACKGROUND: Recently, a novel HOXB13 variant (X285K) was observed in men of African descent with prostate cancer (PCa) in Martinique. Little is known about this or other variants in HOXB13 which may play a role in PCa susceptibility in African-Americ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::236b4ced39c31b97307fadf40bf42dd5
https://europepmc.org/articles/PMC8888559/
https://europepmc.org/articles/PMC8888559/
Autor:
Marta Gielzak, Patrick C. Walsh, Kathleen E. Wiley, Shuwei Li, Brice A. J. Sarver, Hongjie Yu, Tamara L. Lotan, Rong Na, Mary Helen Black, Brian T. Helfand, Yishuo Wu, William B. Isaacs, Siqun Zheng, Kathleen A. Cooney, Jianfeng Xu, Holly LaDuca
Publikováno v:
Journal of Urology. 203
Autor:
S. Lilly Zheng, Hongjie Yu, Marta Gielzak, Patrick C. Walsh, Yishuo Wu, Brian T. Helfand, Tamara L. Lotan, Kathleen E. Wiley, Shuwei Li, Mary Helen Black, William B. Isaacs, Holly LaDuca, Jianfeng Xu, Brice A. J. Sarver, Rong Na, Kathleen A. Cooney
Publikováno v:
European urology oncology. 3(2)
Background Rare germline mutations in several genes, primarily DNA repair genes, have been proposed to predict worse prognosis of prostate cancer (PCa). Objective To compare the frequency of germline pathogenic mutations in commonly assayed PCa genes
Autor:
Charles M. Ewing, Seong Tae Kim, Junjie Feng, Y. Yan, Jishan Sun, Zheng Zhang, Zhong Wang, Guangchao Sui, Lars Egevad, Siqun Zheng, Meimei Wan, Jun Luo, Jianfeng Xu, Robert L. Vessella, Scott D. Cramer, Tao Li, Guifang Yan, Chunmei C. Xie, Marta Gielzak, G. S. Bova, Wennuan Liu, Aubrey R. Turner, W. Isaacs, Henrik Grönberg, Johan Lindberg
Publikováno v:
Oncogene. 31:3939-3948
A clearer definition of the molecular determinants that drive the development and progression of prostate cancer (PCa) is urgently needed. Efforts to map recurrent somatic deletions in the tumor genome, especially homozygous deletions (HODs), have pr
Autor:
Yu Cheng, Henrik Grönberg, Ge Li, David Duggan, Robin Gurganus, Jielin Sun, Marta Gielzak, Jurga Sauvageot, Patrick C. Walsh, Alan W. Partin, Leslie A. Mangold, Yi Zhu, Kathleen E. Wiley, S. Lilly Zheng, Guifang Yan, Sarah D. Isaacs, John D. Carpten, Wennuan Liu, Bruce J. Trock, Fang-Chi Hsu, Aubrey R. Turner, Jin Woo Kim, Huann-Sheng Chen, Bao Li Chang, William B. Isaacs, Jianfeng Xu
Publikováno v:
JNCI: Journal of the National Cancer Institute. 99:1525-1533
Recent studies have provided evidence of associations between genetic markers at human chromosome 8q24 and an increased risk of prostate cancer. We examined whether multiple independent risk variants exist in this region and whether the strength of o
Autor:
Daniel J, Schaid, Shannon K, McDonnell, Katherine E, Zarfas, Julie M, Cunningham, Scott, Hebbring, Stephen N, Thibodeau, Rosalind A, Eeles, Douglas F, Easton, William D, Foulkes, Jacques, Simard, Graham G, Giles, John L, Hopper, Lovise, Mahle, Pal, Moller, Michael, Badzioch, D Timothy, Bishop, Chris, Evans, Steve, Edwards, Julia, Meitz, Sarah, Bullock, Questa, Hope, Michelle, Guy, Chih-lin, Hsieh, Jerry, Halpern, Raymond R, Balise, Ingrid, Oakley-Girvan, Alice S, Whittemore, Jianfeng, Xu, Latchezar, Dimitrov, Bao-Li, Chang, Tamara S, Adams, Aubrey R, Turner, Deborah A, Meyers, Danielle M, Friedrichsen, Kerry, Deutsch, Suzanne, Kolb, Marta, Janer, Leroy, Hood, Elaine A, Ostrander, Janet L, Stanford, Charles M, Ewing, Marta, Gielzak, Sarah D, Isaacs, Patrick C, Walsh, Kathleen E, Wiley, William B, Isaacs, Ethan M, Lange, Lindsey A, Ho, Jennifer L, Beebe-Dimmer, David P, Wood, Kathleen A, Cooney, Daniela, Seminara, Tarja, Ikonen, Agnes, Baffoe-Bonnie, Henna, Fredriksson, Mika P, Matikainen, Teuvo L J, Tammela, Joan, Bailey-Wilson, Johanna, Schleutker, Christiane, Maier, Kathleen, Herkommer, Josef J, Hoegel, Walther, Vogel, Thomas, Paiss, Fredrik, Wiklund, Monica, Emanuelsson, Elisabeth, Stenman, Björn-Anders, Jonsson, Henrik, Grönberg, Nicola J, Camp, James, Farnham, Lisa A, Cannon-Albright, William J, Catalona, Brian K, Suarez, Kimberly A, Roehl
Publikováno v:
Human Genetics. 120:471-485
While it is widely appreciated that prostate cancers vary substantially in their propensity to progress to a life-threatening stage, the molecular events responsible for this progression have not been identified. Understanding these molecular mechani
Autor:
Thomas Paiss, Steven J. Jacobsen, Kirsten White, Johanna Schleutker, Jurga Sauvageot, Scott J. Hebbring, Christiane Maier, Henna Fredriksson, Walther Vogel, Ville Autio, Daniel J. Schaid, James R. Cerhan, Tarja Ikonen, Kathleen Herkommer, William B. Isaacs, Marta Gielzak, Stephen N. Thibodeau, Kathleen A. Cooney, Teuvo L.J. Tammela, Charles M. Ewing, Shannon K. McDonnell
Publikováno v:
Cancer Epidemiology, Biomarkers & Prevention. 15:935-938
The Nijmegen breakage syndrome 1 (NBS1) gene, which participates in DNA double strand break repair, has been postulated to be a susceptibility factor for a number of cancers, including prostate cancer. Numerous mutations have been identified in NBS1,
Autor:
Charles M. Ewing, Anna M. Ray, Ethan M. Lange, Kimberly A. Zuhlke, Christiane M. Robbins, Waibhav D. Tembe, Kathleen E. Wiley, Sarah D. Isaacs, Dorhyun Johng, Yunfei Wang, Chris Bizon, Guifang Yan, Marta Gielzak, Alan W. Partin, Vijayalakshmi Shanmugam, Tyler Izatt, Shripad Sinari, David W. Craig, S. Lilly Zheng, Patrick C. Walsh, James E. Montie, Jianfeng Xu, John D. Carpten, William B. Isaacs, Kathleen A. Cooney
Publikováno v:
The New England journal of medicine. 366(2)
Family history is a significant risk factor for prostate cancer, although the molecular basis for this association is poorly understood. Linkage studies have implicated chromosome 17q21-22 as a possible location of a prostate-cancer susceptibility ge