Zobrazeno 1 - 10 of 48 pro vyhledávání: '"Mart Dela Cruz"'
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Akademický článek
Exercise-induced myokines downregulates the ACE2 level in bronchial epithelial cells: Implications for SARS-CoV-2 prevention.
Autor: Vaishali Bhardwaj, Mart Dela Cruz, Deepika Subramanyam, Rohit Kumar, Sandeep Markan, Beth Parker, Hemant K Roy
Publikováno v: PLoS ONE, Vol 17, Iss 7, p e0271303 (2022)
BackgroundThe Covid-19 pandemic has emerged as the leading public health challenge of our time (20th century). While vaccinations have finally blunted the death rate, concern has remained about more virulent forms highlighting the need for alternativ
Externí odkaz: https://doaj.org/article/9f259a352ce04aeba43c27e4cd29bd59
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2
Colonic Epithelial Angiotensin-Converting Enzyme 2 (ACE2) Expression in Blacks and Whites: Potential Implications for Pathogenesis Covid-19 Racial Disparities
Autor: Caroline Zaworski, Deepika Subramanyan, Vaishali Bhardwaj, Hemant K. Roy, Mart Dela Cruz, Priya Roy, David Nunes
Publikováno v: Journal of Racial and Ethnic Health Disparities
Background Covid-19 toll is disproportionate in Blacks although the mechanisms remain incompletely understood. From a biological perspective, several host proteins have received most attention as logical susceptibility targets. Specifically, angioten
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd2ddf84e0c3d613874fabc091ab1a2b
https://doi.org/10.1007/s40615-021-01004-9
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4
Metabolic reprogramming of the premalignant colonic mucosa is an early event in carcinogenesis
Autor: Sanjib Chowdhury, Anisha Varma-Wilson, Christopher S. Huang, Swati Bhattacharya, Sarah E. Ledbetter, Charles M. Bliss, Navneet Momi, Mart Dela Cruz, Hemant K. Roy, Vadim Backman, David R. Lichtenstein, Ashish K. Tiwari, Ramesh K. Wali
Publikováno v: Oncotarget
// Mart Dela Cruz 1,* , Sarah Ledbetter 1,* , Sanjib Chowdhury 1,* , Ashish K. Tiwari 1 , Navneet Momi 1 , Ramesh K. Wali 1 , Charles Bliss 1 , Christopher Huang 1 , David Lichtenstein 1 , Swati Bhattacharya 1 , Anisha Varma-Wilson 1 , Vadim Backman
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f400dd3ea5454bd5835987fc3ac2fbc6
https://doi.org/10.18632/oncotarget.16129
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5
Akademický článek
HDAC up-regulation in early colon field carcinogenesis is involved in cell tumorigenicity through regulation of chromatin structure.
Autor: Yolanda Stypula-Cyrus, Dhwanil Damania, Dhananjay P Kunte, Mart Dela Cruz, Hariharan Subramanian, Hemant K Roy, Vadim Backman
Publikováno v: PLoS ONE, Vol 8, Iss 5, p e64600 (2013)
Normal cell function is dependent on the proper maintenance of chromatin structure. Regulation of chromatin structure is controlled by histone modifications that directly influence chromatin architecture and genome function. Specifically, the histone
Externí odkaz: https://doaj.org/article/96c0cd6b3f424692890b7f0cad08b12b
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6
Single Nucleotide Polymorphism Facilitated Down-Regulation of the Cohesin Stromal Antigen-1: Implications for Colorectal Cancer Racial Disparities
Autor: Richard Sherva, Vadim Backman, Sanjib Chowdhury, Somenath Datta, Michelle T. Long, Mart Dela Cruz, Priya Roy, Hemant K. Roy
Publikováno v: Neoplasia: An International Journal for Oncology Research, Vol 20, Iss 3, Pp 289-294 (2018)
Neoplasia (New York, N.Y.)
The biological underpinnings for racial disparities in colorectal cancer (CRC) incidence remain to be elucidated. We have previously reported that the cohesin SA-1 down-regulation is an early event in colon carcinogenesis which is dramatically accent
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef398be008662e5c61cf07afae96e7c5
http://www.sciencedirect.com/science/article/pii/S1476558617304542
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7
Abstract C036: Cohesins and colorectal cancer (CRC): Modulation of CRC stem cells and chemoresistance by STAG1 with race-specific implications
Autor: Somenath Datta, Sanjib Chowdhury, Hemant K. Roy, Caroline Zaworski, Mart Dela Cruz
Publikováno v: Cancer Epidemiology, Biomarkers & Prevention. 29:C036-C036
Despite advances in treatment and early detective measures for colorectal cancer (CRC), African-Americans (AAs) suffer disproportionately from CRC (~25% higher incidence and ~50% higher mortality) than Caucasians. Furthermore, AAs tend to receive ear
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b53b4ff1b5afa80a5142f585685a3aa0
https://doi.org/10.1158/1538-7755.disp18-c036
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8
Higher Order Chromatin Modulator Cohesin SA1 Is an Early Biomarker for Colon Carcinogenesis: Race-Specific Implications
Autor: Vadim Backman, Ashish K. Tiwari, Andrew J. Radosevich, Christopher R. Weber, Navneet Momi, Anuj Chhaparia, Hemant K. Roy, Bilal Latif, Audrey H. Calderwood, Yolanda Stypula-Cyrus, Ramesh K. Wali, Mart Dela Cruz, Luay M. Almassalha
Publikováno v: Cancer Prevention Research. 9:844-854
Alterations in high order chromatin, with concomitant modulation in gene expression, are one of the earliest events in the development of colorectal cancer. Cohesins are a family of proteins that modulate high-order chromatin, although the role in co
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2863d41593c5d0a45bca35fc2fa48e2d
https://doi.org/10.1158/1940-6207.capr-16-0054
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