Spatial multi-omics in whole skeletal muscle reveals complex tissue architecture.

Autor: Martínez Mir C; Department of Anatomy and Embryology, Leiden University Medical Center, 2333, Leiden, The Netherlands.; The Novo Nordisk Foundation Center for Stem Cell Medicine (reNEW), Leiden Node, Leiden, The Netherlands., Pisterzi P; Department of Anatomy and Embryology, Leiden University Medical Center, 2333, Leiden, The Netherlands.; The Novo Nordisk Foundation Center for Stem Cell Medicine (reNEW), Leiden Node, Leiden, The Netherlands., De Poorter I; Department of Anatomy and Embryology, Leiden University Medical Center, 2333, Leiden, The Netherlands.; The Novo Nordisk Foundation Center for Stem Cell Medicine (reNEW), Leiden Node, Leiden, The Netherlands., Rilou M; Department of Anatomy and Embryology, Leiden University Medical Center, 2333, Leiden, The Netherlands.; The Novo Nordisk Foundation Center for Stem Cell Medicine (reNEW), Leiden Node, Leiden, The Netherlands., van Kranenburg M; Department of Anatomy and Embryology, Leiden University Medical Center, 2333, Leiden, The Netherlands.; The Novo Nordisk Foundation Center for Stem Cell Medicine (reNEW), Leiden Node, Leiden, The Netherlands., Heijs B; The Novo Nordisk Foundation Center for Stem Cell Medicine (reNEW), Leiden Node, Leiden, The Netherlands.; Center of Proteomics and Metabolomics, Leiden University Medical Center, Leiden, The Netherlands.; Bruker Daltonics GmbH & Co. KG, Bremen, Germany., Alemany A; Department of Anatomy and Embryology, Leiden University Medical Center, 2333, Leiden, The Netherlands.; The Novo Nordisk Foundation Center for Stem Cell Medicine (reNEW), Leiden Node, Leiden, The Netherlands., Sage F; Department of Anatomy and Embryology, Leiden University Medical Center, 2333, Leiden, The Netherlands. f.g.sage@lumc.nl.; The Novo Nordisk Foundation Center for Stem Cell Medicine (reNEW), Leiden Node, Leiden, The Netherlands. f.g.sage@lumc.nl., Geijsen N; Department of Anatomy and Embryology, Leiden University Medical Center, 2333, Leiden, The Netherlands. n.geijsen@lumc.nl.; The Novo Nordisk Foundation Center for Stem Cell Medicine (reNEW), Leiden Node, Leiden, The Netherlands. n.geijsen@lumc.nl.

Publikováno v: Communications biology [Commun Biol] 2024 Oct 05; Vol. 7 (1), pp. 1272. Date of Electronic Publication: 2024 Oct 05.

Revealing the spatio-phenotypic patterning of cells in healthy and tumor tissues with mLSR-3D and STAPL-3D.

Autor: van Ineveld RL; Princess Máxima Center for Pediatric Oncology, Utrecht, the Netherlands.; Cancer Genomics Netherlands, Oncode Institute, Utrecht, the Netherlands., Kleinnijenhuis M; Princess Máxima Center for Pediatric Oncology, Utrecht, the Netherlands.; Cancer Genomics Netherlands, Oncode Institute, Utrecht, the Netherlands., Alieva M; Princess Máxima Center for Pediatric Oncology, Utrecht, the Netherlands.; Cancer Genomics Netherlands, Oncode Institute, Utrecht, the Netherlands., de Blank S; Princess Máxima Center for Pediatric Oncology, Utrecht, the Netherlands.; Cancer Genomics Netherlands, Oncode Institute, Utrecht, the Netherlands., Barrera Roman M; Princess Máxima Center for Pediatric Oncology, Utrecht, the Netherlands.; Cancer Genomics Netherlands, Oncode Institute, Utrecht, the Netherlands., van Vliet EJ; Princess Máxima Center for Pediatric Oncology, Utrecht, the Netherlands.; Cancer Genomics Netherlands, Oncode Institute, Utrecht, the Netherlands., Martínez Mir C; Princess Máxima Center for Pediatric Oncology, Utrecht, the Netherlands.; Cancer Genomics Netherlands, Oncode Institute, Utrecht, the Netherlands., Johnson HR; Princess Máxima Center for Pediatric Oncology, Utrecht, the Netherlands.; Cancer Genomics Netherlands, Oncode Institute, Utrecht, the Netherlands., Bos FL; Princess Máxima Center for Pediatric Oncology, Utrecht, the Netherlands.; Cancer Genomics Netherlands, Oncode Institute, Utrecht, the Netherlands., Heukers R; QVQ Holding BV, Utrecht, the Netherlands., Chuva de Sousa Lopes SM; Department of Anatomy and Embryology, Leiden University Medical Center, Leiden, the Netherlands., Drost J; Princess Máxima Center for Pediatric Oncology, Utrecht, the Netherlands.; Cancer Genomics Netherlands, Oncode Institute, Utrecht, the Netherlands., Dekkers JF; Princess Máxima Center for Pediatric Oncology, Utrecht, the Netherlands.; Cancer Genomics Netherlands, Oncode Institute, Utrecht, the Netherlands., Wehrens EJ; Princess Máxima Center for Pediatric Oncology, Utrecht, the Netherlands.; Cancer Genomics Netherlands, Oncode Institute, Utrecht, the Netherlands., Rios AC; Princess Máxima Center for Pediatric Oncology, Utrecht, the Netherlands. a.c.rios@prinsesmaximacentrum.nl.; Cancer Genomics Netherlands, Oncode Institute, Utrecht, the Netherlands. a.c.rios@prinsesmaximacentrum.nl.

Publikováno v: Nature biotechnology [Nat Biotechnol] 2021 Oct; Vol. 39 (10), pp. 1239-1245. Date of Electronic Publication: 2021 Jun 03.

Tumor microenvironment-like conditions alter pancreatic cancer cell metabolism and behavior.

Autor: Gardner, Georgina Louise, Stuart, Jeffrey Alan

Publikováno v: American Journal of Physiology: Cell Physiology; Oct2024, Vol. 327 Issue 4, pC959-C978, 20p